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Bontoxilysin-A
go.drugbank.com/bio_entities/BE0004102TargetClostridium botulinumPolypeptides: Bontoxilysin-ASynonyms: A, boNT/AFilamin-A
go.drugbank.com/bio_entities/BE0009099TargetHumansAnchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.
Polypeptides: Filamin-ASynonyms: FLN-AToxin A
go.drugbank.com/bio_entities/BE0010938TargetPeptoclostridium difficileToxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains
Polypeptides: Toxin ATragacanth
go.drugbank.com/drugs/DB10667ApprovedTragacanth allergenic extract is used in allergenic testing.
Synonyms: Goat thorn bush resin, Astragalus gummifer resinCategories: Compounds used in a research, industrial, or household settingInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnInterferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.
Synonyms: Interferon Alfa 2A, Interferon alfa-2aInternational brands: Roferon AImmunoglobulin A Nephropathy
go.drugbank.com/conditions/DBCOND0063172Drugs: AtrasentanSynonyms: Immunoglobulin A NephropathyDeficiency, Vitamin A
go.drugbank.com/conditions/DBCOND0085163Drugs: Ascorbic acid · Beta carotene · Cholecalciferol · Cod liver oil · Ergocalciferol · Vitamin A +1 moreSynonyms: Hypovitaminosis A, Deficiency, Vitamin AReviparin
go.drugbank.com/drugs/DB09259ApprovedReviparin has a molecular weight of 3.9 kDa.[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469] … Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin.
Products: CLIVARIN 5726 IE A XA/ML, CLIVARODI 17178 A XA/MLPetrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: Vitamin A D, Vitamin A DCategories: Compounds used in a research, industrial, or household setting