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Displaying results 7421 - 7430 of 10000 in total
  1. Target

    Putative inactive carboxylesterase 4

    go.drugbank.com/bio_entities/BE0004349
    TargetHumans

    Has no esterase activity

    Polypeptides: Putative inactive carboxylesterase 4Synonyms: PCE-3, Placental carboxylesterase 3
  2. Target

    Adenylate kinase 4, mitochondrial

    go.drugbank.com/bio_entities/BE0004780
    EnzymeHumans

    Broad-specificity mitochondrial nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions (PubMed:19073142, PubMed:19766732, PubMed:23416111, PubMed:24767988). Similar to ...

    Polypeptides: Adenylate kinase 4, mitochondrialSynonyms: Adenylate kinase 3-like
  3. Target

    Bone morphogenetic protein 4

    go.drugbank.com/bio_entities/BE0009000
    TargetHumans

    Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis (PubMed:31363885). Acts in concert with PTHLH/PTHRP to stim...

    Polypeptides: Bone morphogenetic protein 4Synonyms: BMP-4
  4. Target

    Somatostatin receptor type 4

    go.drugbank.com/bio_entities/BE0009273
    TargetHumans

    Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate re...

    Polypeptides: Somatostatin receptor type 4Synonyms: SS-4-R
  5. Target

    Phosphatidylinositol 4-kinase beta

    go.drugbank.com/bio_entities/BE0009513
    TargetHumans

    Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phospho...

    Polypeptides: Phosphatidylinositol 4-kinase betaSynonyms: PtdIns 4-kinase beta
  6. Target

    Delta-like protein 4

    go.drugbank.com/bio_entities/BE0010485
    TargetHumans

    Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313...

    Polypeptides: Delta-like protein 4Synonyms: Drosophila Delta homolog 4
  7. Target

    Melanoma-associated antigen 4

    go.drugbank.com/bio_entities/BE0010534
    TargetHumans

    Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). Also negatively regulates p53-mediated apoptosis (PubMed:22842486)

    Polypeptides: Melanoma-associated antigen 4Synonyms: MAGE-4 antigen
  8. Target

    Alpha-(1,3)-fucosyltransferase 4

    go.drugbank.com/bio_entities/BE0012925
    EnzymeHumans

    Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked … In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (PubMed:11278338, PubMed:1716630

    Polypeptides: Alpha-(1,3)-fucosyltransferase 4Synonyms: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Fucosyltransferase 4
  9. Target

    Double homeobox protein 4

    go.drugbank.com/bio_entities/BE0020504
    TargetHumans

    Binds to double-stranded DNA elements with the consensus sequence 5'-TAATCTAATCA-3' (PubMed:28459454, PubMed:28459457, PubMed:29572508, PubMed:30315230, PubMed:30540931).

    Polypeptides: Double homeobox protein 4
  10. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Mixtures: Adventure Medical Kits 1-4 Person First Aid, Anti-bacterial Hand Sanitizer 3 Pack 2Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers