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Displaying results 751 - 760 of 10000 in total
  1. Target

    Thyroid hormone receptor alpha

    go.drugbank.com/bio_entities/BE0000687
    TargetHumans

    Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine

    Polypeptides: Thyroid hormone receptor alphaSynonyms: Nuclear receptor subfamily 1 group A member 1
  2. Target

    Cysteinyl leukotriene receptor 1

    go.drugbank.com/bio_entities/BE0000705
    TargetHumans

    Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma.

    Polypeptides: Cysteinyl leukotriene receptor 1Synonyms: LTD4 receptor, G protein-coupled receptor HG55
  3. Target

    Epidermal growth factor receptor

    go.drugbank.com/bio_entities/BE0000767
    TargetEnzymeHumans

    Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling (PubMed:11602604). … Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:10805725, PubMed:12297050,

    Polypeptides: Epidermal growth factor receptorSynonyms: Receptor tyrosine-protein kinase erbB-1
  4. Target

    Metabotropic glutamate receptor 1

    go.drugbank.com/bio_entities/BE0000824
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 1Function: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
  5. Target

    Metabotropic glutamate receptor 4

    go.drugbank.com/bio_entities/BE0000833
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 4Function: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
  6. Target

    Metabotropic glutamate receptor 8

    go.drugbank.com/bio_entities/BE0000835
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 8Function: G protein-coupled receptor activity
  7. Target

    Hepatocyte growth factor receptor

    go.drugbank.com/bio_entities/BE0000915
    TargetHumans

    Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.

    Polypeptides: Hepatocyte growth factor receptorSynonyms: HGF receptor, SF receptor
  8. Target

    Endothelial protein C receptor

    go.drugbank.com/bio_entities/BE0001161
    TargetHumans

    Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation

    Polypeptides: Endothelial protein C receptorSynonyms: APC receptor, Activated protein C receptor
  9. Target

    Toll-like receptor 2

    go.drugbank.com/bio_entities/BE0001164
    TargetHumans

    MAPK activation in response to bacterial peptidoglycan also occurs via this receptor (PubMed:16622205). … Stimulation of monocytes in vitro with M.tuberculosis PstS1 induces p38 MAPK and ERK1/2 activation primarily via this receptor, but also partially via TLR4 (PubMed:16622205).

    Polypeptides: Toll-like receptor 2Synonyms: Toll/interleukin-1 receptor-like protein 4
  10. Target

    Metabotropic glutamate receptor 5

    go.drugbank.com/bio_entities/BE0001192
    TargetHumans

    G protein-coupled receptor for glutamate.

    Polypeptides: Metabotropic glutamate receptor 5Function: A2A adenosine receptor binding