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Displaying results 7681 - 7690 of 10000 in total
  1. Target

    Interleukin-2 receptor subunit alpha

    go.drugbank.com/bio_entities/BE0000658
    TargetHumans

    Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.

    Polypeptides: Interleukin-2 receptor subunit alphaSynonyms: IL-2-RA, IL-2 receptor subunit alpha
  2. Target

    Glycine receptor subunit alpha-2

    go.drugbank.com/bio_entities/BE0000745
    TargetHumans

    Subunit of heteromeric glycine-gated chloride channels (PubMed:15302677, PubMed:16144831, PubMed:2155780, PubMed:23895467, PubMed:25445488, PubMed:26370147, PubMed:34473954). Plays a role in synaptic plasticity (By similarity). Contribut...

    Polypeptides: Glycine receptor subunit alpha-2
  3. Target

    Ephrin type-A receptor 2

    go.drugbank.com/bio_entities/BE0000841
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the re...

    Polypeptides: Ephrin type-A receptor 2
  4. Target

    Receptor activity-modifying protein 2

    go.drugbank.com/bio_entities/BE0000860
    TargetHumans

    Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:9620797). Required for the transpo...

    Polypeptides: Receptor activity-modifying protein 2Synonyms: CRLR activity-modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2
  5. Target

    Protein-tyrosine kinase 2-beta

    go.drugbank.com/bio_entities/BE0000871
    TargetHumans

    Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.

    Polypeptides: Protein-tyrosine kinase 2-betaSynonyms: FADK 2, Focal adhesion kinase 2
  6. Target

    2-dehydro-3-deoxyphosphooctonate aldolase

    go.drugbank.com/bio_entities/BE0001394
    TargetShigella flexneri

    Polypeptides: 2-dehydro-3-deoxyphosphooctonate aldolaseSynonyms: Phospho-2-dehydro-3-deoxyoctonate aldolase
  7. Target

    2-oxopropyl-CoM reductase, carboxylating

    go.drugbank.com/bio_entities/BE0001784
    TargetXanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)

    Catalyzes the reductive cleavage of the thioether bond of 2-oxopropyl-coenzyme M (2-KPC), and the subsequent carboxylation of the ketopropyl cleavage product, yielding the products acetoacetate and free

    Polypeptides: 2-oxopropyl-CoM reductase, carboxylatingSynonyms: 2-KPCC, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase
  8. Target

    3-methyl-2-oxobutanoate hydroxymethyltransferase

    go.drugbank.com/bio_entities/BE0001822
    TargetNeisseria meningitidis serogroup B (strain MC58)

    Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

    Polypeptides: 3-methyl-2-oxobutanoate hydroxymethyltransferaseFunction: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
  9. Target

    Fructose-bisphosphate aldolase class 2

    go.drugbank.com/bio_entities/BE0002021
    TargetEscherichia coli (strain K12)

    Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (PubMed:...

    Polypeptides: Fructose-bisphosphate aldolase class 2
  10. Target

    Vesicle-associated membrane protein 2

    go.drugbank.com/bio_entities/BE0002137
    TargetHumans

    SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for intracellular membrane fusion. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, paralle...

    Polypeptides: Vesicle-associated membrane protein 2Synonyms: VAMP-2, Synaptobrevin-2