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Displaying results 7751 - 7760 of 10000 in total
  1. Target

    Fructose-1,6-bisphosphatase isozyme 2

    go.drugbank.com/bio_entities/BE0011215
    TargetEnzymeHumans

    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate

    Polypeptides: Fructose-1,6-bisphosphatase isozyme 2Synonyms: FBPase 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase 2
  2. Target

    Eukaryotic elongation factor 2 kinase

    go.drugbank.com/bio_entities/BE0011325
    TargetHumans

    Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, ...

    Polypeptides: Eukaryotic elongation factor 2 kinaseSynonyms: eEF-2 kinase, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
  3. Target

    Sphingosine 1-phosphate receptor 2

    go.drugbank.com/bio_entities/BE0012208
    TargetHumans

    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617, PubMed:25274307). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617). When...

    Polypeptides: Sphingosine 1-phosphate receptor 2Synonyms: S1P receptor 2, S1P receptor Edg-5
  4. Target

    N-formyl peptide receptor 2

    go.drugbank.com/bio_entities/BE0012843
    TargetHumans

    Pattern recognition G protein-coupled receptor (GPCR) that recognizes peptides with N-terminal formyl methionine, which are derived from invading pathogens or host mitochondria as pathogen or damage-associated molecular patterns (PAMPs a...

    Polypeptides: N-formyl peptide receptor 2
  5. Target

    Transmembrane channel-like protein 2

    go.drugbank.com/bio_entities/BE0017488
    TargetHumans

    Pore-forming subunit of the mechanotransducer (MET) non-selective cation channel complex located at the tips of stereocilia of cochlear hair cells and that mediates sensory transduction in the auditory system (PubMed:11850618). The MET c...

    Polypeptides: Transmembrane channel-like protein 2Synonyms: Transmembrane cochlear-expressed protein 2
  6. Target

    Insulin-induced gene 2 protein

    go.drugbank.com/bio_entities/BE0021304
    TargetHumans

    Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR (PubMed:12242332, PubMed:16606821, PubMed:32322062). Acts as ...

    Polypeptides: Insulin-induced gene 2 proteinSynonyms: INSIG-2
  7. Target

    Gap junction delta-2 protein

    go.drugbank.com/bio_entities/BE0023585
    TargetHumans

    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell

    Polypeptides: Gap junction delta-2 protein
  8. Target

    Beta (β)-2 integrin (ITGB2)

    go.drugbank.com/bio_entities/BE0027979
    TargetHumans

  9. Target

    Cationic amino acid transporter 2

    go.drugbank.com/bio_entities/BE0000562
    TargetTransporterHumans

    Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by alternative splicing (PubMed:286847...

    Polypeptides: Cationic amino acid transporter 2Synonyms: CAT-2, Solute carrier family 7 member 2
  10. Target

    Interleukin-2 receptor subunit beta

    go.drugbank.com/bio_entities/BE0000651
    TargetHumans

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.

    Polypeptides: Interleukin-2 receptor subunit betaSynonyms: IL-2 receptor subunit beta, High affinity IL-2 receptor subunit beta