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Displaying results 791 - 800 of 10000 in total
  1. Drug

    Drometrizole trisiloxane

    go.drugbank.com/drugs/DB11585
    Approved

    The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved for use in the EU, Canada, Australia … Despite being used elsewhere in the world with relatively few reports of adverse reactions, the FDA continues to cite that the existing scientific record is not sufficient to establish the compound as

    Mixtures: Garnier Ombrelle Kids Wet N Protect Hypoallergenic SPF 45 Mexoryl Technology, Garnier Ombrelle Kids Wet N Protect Hypoallergenic SPF 45 Mexoryl TechnologyCategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-Ring
  2. Indication

    Rhabdomyosarcoma

    go.drugbank.com/conditions/DBCOND0016166
    Drugs: Dactinomycin · Irinotecan · Vincristine
    Synonyms: Rhabdomyosarcoma, no subtype
  3. Drug

    Isotretinoin

    go.drugbank.com/drugs/DB00982
    ApprovedInvestigational

    [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574] … Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.

    Mixtures: ISOTREXIN JEL, 30 G, ETREXİN % 2 + % 0.05 JELCategories: Retinoids for Topical Use in Acne, Cytochrome P-450 Substrates
  4. Indication

    Hodgkin's Lymphoma

    go.drugbank.com/conditions/DBCOND0030382
    Drugs: Bleomycin · Chlorambucil · Cyclophosphamide · Dacarbazine · Doxorubicin · Gemcitabine +5 more
    Synonyms: Hodgkin lymphoma, no ICD-O subtype, Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)
  5. Indication

    Chronic Myelogenous Leukemia (CML)

    go.drugbank.com/conditions/DBCOND0040386
    Drugs: Busulfan · Hydroxyurea · Interferon alfa-2a
    Synonyms: Chronic myelogenous leukemia, no ICD-O subtype, Chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)
  6. Drug

    Benzydamine

    go.drugbank.com/drugs/DB09084
    ApprovedInvestigational

    aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties. … Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base.

    Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 MLCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal
  7. Drug

    Ticagrelor

    go.drugbank.com/drugs/DB08816
    ApprovedInvestigational

    [A2903] Unlike [clopidogrel], ticagrelor is not a prodrug.[A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU,[L14207]. … Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y<sub>12</sub> receptor antagonism.

    Synonyms: (1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diolCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  8. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    [L5110] On the other hand, the combination treatment of carbidopa/levodopa was originally developed by Watson Labs but the historical information by the FDA brings back to the approval of this combination … An individual formulation containing solely carbidopa was generated to treat nausea in patients where the combination therapy [levodopa]/carbidopa is not efficient reducing nausea.

    Mixtures: LEVODO CA E P100/25/200, LEVODO CA E P100/25/200Categories: Aromatic L-amino Acid Decarboxylase Inhibitors
  9. Drug

    Linezolid

    go.drugbank.com/drugs/DB00601
    ApprovedInvestigational

    Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSynonyms: N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide
  10. Drug

    Metelimumab

    go.drugbank.com/drugs/DB18695
    Experimental

    Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.

    Synonyms: Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4-chain)), disulfide with human monoclonal cat-192 .kappa.-chain, dimer, Human anti-transforming growth factor beta 1 monoclonal antibody