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Bontoxilysin-A
go.drugbank.com/bio_entities/BE0004102TargetClostridium botulinumPolypeptides: Bontoxilysin-ASynonyms: A, boNT/AFilamin-A
go.drugbank.com/bio_entities/BE0009099TargetHumansAnchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. … Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs.
Polypeptides: Filamin-ASynonyms: FLN-AToxin A
go.drugbank.com/bio_entities/BE0010938TargetPeptoclostridium difficileToxin A Precursor of a cytotoxin that targets and disrupts the colonic epithelium, inducing the host inflammatory and innate immune responses and resulting in diarrhea and pseudomembranous colitis … Once entered into host cells, acidification in the endosome promotes the membrane insertion of the translocation region and formation of a pore, leading to translocation of the GT44 and peptidase C80 domains
Polypeptides: Toxin ALidocaine
go.drugbank.com/drugs/DB00281ApprovedInvestigationalVet approvedIn particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local anesthesia for a large variety … As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468].
Synonyms: 2-(Diethylamino)-2',6'-acetoxylidide, 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideInternational brands: L-Caine, Lidoject-1Benzalkonium
go.drugbank.com/drugs/DB11105ApprovedInvestigationalBenzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. … This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal drops or sprays as an excipient ingredient serving as an antimicrobial preservative [FDA Label]
Mixtures: Holy Water Mercy In A Bottle, Keepan ACategories: Compounds used in a research, industrial, or household settingHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnHepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. … Hepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs either as a co-infection or super-infection in a HBsAg carrier.
Synonyms: Hepatitis B antigen, Hepatitis B VaccineSalts: Hepatitis B virus subtype ADW HBSAG surface protein antigen, Hepatitis B virus subtype ADW2 HBSAG surface protein antigenImmunoglobulin A Nephropathy
go.drugbank.com/conditions/DBCOND0063172Drugs: AtrasentanSynonyms: Immunoglobulin A NephropathyDeficiency, Vitamin A
go.drugbank.com/conditions/DBCOND0085163Drugs: Ascorbic acid · Beta carotene · Cholecalciferol · Cod liver oil · Ergocalciferol · Vitamin A +1 moreSynonyms: Hypovitaminosis A, Deficiency, Vitamin AHaloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigationalIn addition, they block many receptors other than the primary target (dopamine receptors), such as cholinergic or histaminergic receptors, resulting in a higher incidence of side effects such as sedation … be caused by a hyperdopaminergic state within the limbic system of the brain.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one