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dTDP-4-dehydrorhamnose 3,5-epimerase
go.drugbank.com/bio_entities/BE0003322TargetMycobacterium tuberculosisCatalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
Polypeptides: dTDP-4-dehydrorhamnose 3,5-epimeraseSynonyms: dTDP-4-keto-6-deoxyglucose 3,5-epimerase, dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimeraseDNA topoisomerase 4 subunit B
go.drugbank.com/bio_entities/BE0003727TargetStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit BProteasome subunit beta type-4
go.drugbank.com/bio_entities/BE0003918TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory parti...
Polypeptides: Proteasome subunit beta type-4Synonyms: Proteasome chain 3Pterin-4-alpha-carbinolamine dehydratase
go.drugbank.com/bio_entities/BE0004555TargetHumansInvolved in tetrahydrobiopterin biosynthesis (By similarity). Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription (By similarity). Regulates the di...
Polypeptides: Pterin-4-alpha-carbinolamine dehydrataseSynonyms: 4-alpha-hydroxy-tetrahydropterin dehydrataseIntracellular hyaluronan-binding protein 4
go.drugbank.com/bio_entities/BE0004943TargetHumansRibosome-binding protein that promotes ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation (By similarity). Acts via its association with EEF2/eEF2 factor ...
Polypeptides: Intracellular hyaluronan-binding protein 4Synonyms: IHABP-4, Hyaluronan-binding protein 4Immunoglobulin heavy constant gamma 4
go.drugbank.com/bio_entities/BE0005089TargetHumansIg gamma-4 (IgG4) isotype does not elicit antibody-dependent cellular cytotoxicity (ADDC) or complement-dependent cytotoxicity (CDC).
Polypeptides: Immunoglobulin heavy constant gamma 4Synonyms: Ig gamma-4 chain C regionInward rectifier potassium channel 4
go.drugbank.com/bio_entities/BE0005187TargetHumansInward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as externa...
Polypeptides: Inward rectifier potassium channel 4Synonyms: IRK-3, Potassium channel, inwardly rectifying subfamily J member 4DNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0008383TargetStaphylococcus aureusTopoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit ACalcium-dependent protein kinase 4
go.drugbank.com/bio_entities/BE0009256TargetPlasmodium falciparum (isolate 3D7)Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:19307175, PubMed:19666141).
Polypeptides: Calcium-dependent protein kinase 4Sphingosine 1-phosphate receptor 4
go.drugbank.com/bio_entities/BE0009882TargetHumansG protein-coupled receptor highly expressed in immune cells, where it regulates immune response and cytokine production. Functions as a receptor for the lysosphingolipid sphingosine-1-phosphate (S1P). Upon S1P binding, promotes regulator...
Polypeptides: Sphingosine 1-phosphate receptor 4Synonyms: S1P receptor 4