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Displaying results 8101 - 8110 of 10000 in total
  1. Target

    DNA polymerase epsilon subunit 4

    go.drugbank.com/bio_entities/BE0003616
    TargetHumans

    Accessory component of the DNA polymerase epsilon complex (PubMed:10801849). Participates in DNA repair and in chromosomal DNA replication (By similarity)

    Polypeptides: DNA polymerase epsilon subunit 4Synonyms: DNA polymerase II subunit 4
  2. Target

    Electrogenic sodium bicarbonate cotransporter 4

    go.drugbank.com/bio_entities/BE0004677
    TransporterHumans

    Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3

    Polypeptides: Electrogenic sodium bicarbonate cotransporter 4Synonyms: Solute carrier family 4 member 5
  3. Target

    DNA topoisomerase 4 subunit B

    go.drugbank.com/bio_entities/BE0008386
    TargetBacillus subtilis (strain 168)

    Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit B
  4. Target

    Secreted frizzled-related protein 4

    go.drugbank.com/bio_entities/BE0009094
    TargetHumans

    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a ...

    Polypeptides: Secreted frizzled-related protein 4Synonyms: sFRP-4
  5. Target

    Sphingolipid delta(4)-desaturase DES1

    go.drugbank.com/bio_entities/BE0011584
    TargetHumans

    Has sphingolipid-delta-4-desaturase activity. Converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (PubMed:11937514, PubMed:30620337, PubMed:30620338).

    Polypeptides: Sphingolipid delta(4)-desaturase DES1
  6. Target

    Transcriptional enhancer factor TEF-4

    go.drugbank.com/bio_entities/BE0014575
    TargetHumans

    Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif … The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1

    Polypeptides: Transcriptional enhancer factor TEF-4Synonyms: TEAD-2, TEA domain family member 2
  7. Pathway

    Acylcarnitine 2-Hydroxy-4-octenoylcarnitine

    smpdb.ca/view/SMP0123376
    Metabolic

    2-Hydroxy-4-octenoylcarnitine is an acylcarnitine. … Once in the matrix, 2-hydroxy-4-octenoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 2-hydroxy-4-octenoyl-CoA and

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  8. Pathway

    Acylcarnitine 2-propylpent-4-enoylcarnitine

    smpdb.ca/view/SMP0123562
    Metabolic

    2-propylpent-4-enoylcarnitine is an acylcarnitine. … Once in the matrix, 2-propylpent-4-enoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 2-propylpent-4-enoyl-CoA and

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  9. Pathway

    Acylcarnitine 4-hydroxy-2-propylpentanoylcarnitine

    smpdb.ca/view/SMP0123565
    Metabolic

    4-hydroxy-2-propylpentanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 4-hydroxy-2-propylpentanoyl-CoA reacts with L-carnitine to form 4-hydroxy-2-propylpentanoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  10. Pathway

    Acylcarnitine 3-[(1S,2R,5S)-5-hydroxy-2-[(1E,3S,5Z,8Z,11Z)-3-hydroxytetradeca-1,5,8,11-tetraen-1-yl]-3-oxocyclopentyl]propanoylcarnitine

    smpdb.ca/view/SMP0123481
    Metabolic

    3-[(1S,2R,5S)-5-hydroxy-2-[(1E,3S,5Z,8Z,11Z)-3-hydroxytetradeca-1,5,8,11-tetraen-1-yl]-3-oxocyclopentyl]propanoylcarnitine is an acylcarnitine. … Once in the matrix, 3-[(1S,2R,5S)-5-hydroxy-2-[(1E,3S,5Z,8Z,11Z)-3-hydroxytetradeca-1,5,8,11-tetraen-1-yl]-3-oxocyclopentyl]propanoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial