Search
CX3C chemokine receptor 1
go.drugbank.com/bio_entities/BE0010049TargetHumansAlso acts as a receptor for C-C motif chemokine CCL26, inducing cell chemotaxis (PubMed:20974991) … Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response
Polypeptides: CX3C chemokine receptor 1Synonyms: Fractalkine receptor, Beta chemokine receptor-like 1Galanin receptor type 1
go.drugbank.com/bio_entities/BE0013287TargetHumansReceptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity
Polypeptides: Galanin receptor type 1Function: galanin receptor activityGastric inhibitory polypeptide receptor
go.drugbank.com/bio_entities/BE0011012TargetHumansThis is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Polypeptides: Gastric inhibitory polypeptide receptorSynonyms: Glucose-dependent insulinotropic polypeptide receptorProteinase-activated receptor 2
go.drugbank.com/bio_entities/BE0010726TargetHumansReceptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). … Believed to be a class B receptor which internalizes as a complex with arrestin and traffic with it to endosomal vesicles, presumably as desensitized receptor, for extended periods of time.
Polypeptides: Proteinase-activated receptor 2Synonyms: Thrombin receptor-like 1, G protein-coupled receptor 11Activin receptor type-1
go.drugbank.com/bio_entities/BE0000264TargetHumansAs a type I receptor, forms heterotetrameric receptor complexes with the type II receptors AMHR2, ACVR2A or ACVR2B (PubMed:17911401). … Bone morphogenetic protein (BMP) type I receptor that is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation
Polypeptides: Activin receptor type-1Synonyms: Activin receptor type I, Activin receptor-like kinase 2Nuclear receptor coactivator 2
go.drugbank.com/bio_entities/BE0003740TargetHumansInvolved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3 (PubMed:23508108).
Polypeptides: Nuclear receptor coactivator 2Function: aryl hydrocarbon receptor bindingMetabotropic glutamate receptor 2
go.drugbank.com/bio_entities/BE0000974TargetHumansDimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate (PubMed:37286794).
Polypeptides: Metabotropic glutamate receptor 2Interferon lambda receptor 1
go.drugbank.com/bio_entities/BE0016547TargetHumansThe IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. … Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Polypeptides: Interferon lambda receptor 1Synonyms: IFN-lambda receptor 1, IL-28 receptor subunit alphaInterleukin-17 receptor D
go.drugbank.com/bio_entities/BE0017358TargetHumansFeedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation (PubMed:12807873, PubMed:12958313). Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK wi...
Polypeptides: Interleukin-17 receptor DSynonyms: IL-17 receptor D, Interleukin-17 receptor-like proteinLysophosphatidic acid receptor 1
go.drugbank.com/bio_entities/BE0017535TargetHumansReceptor for lysophosphatidic acid (LPA) (PubMed:19306925, PubMed:25025571, PubMed:26091040, PubMed:9070858). … Through its function as LPA receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding (PubMed:18066075, PubMed:19656035, PubMed:19733258).
Polypeptides: Lysophosphatidic acid receptor 1Synonyms: LPA receptor 1, Lysophosphatidic acid receptor Edg-2