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Cyclopropane mycolic acid synthase 2
go.drugbank.com/bio_entities/BE0001211TargetMycobacterium tuberculosiscyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine
Synonyms: S-adenosylmethionine-dependent methyltransferaseCyclopropane mycolic acid synthase 3
go.drugbank.com/bio_entities/BE0002521TargetMycobacterium tuberculosisCatalyzes the conversion of a double bond to a cyclopropane ring at the proximal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.
Synonyms: S-adenosylmethionine-dependent methyltransferaseNeuronal Acetylcholine (nACh) Receptor Subunits
go.drugbank.com/bio_entities/BE0009927TargetHumansby a collection of nAChR subunits. … Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability. nAChRs are excitatory neurotrasnmitter receptors formed
Synonyms: nAChR7, NACHR alpha-10AZD-8330
go.drugbank.com/drugs/DB06061InvestigationalAZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival.
Categories: Heterocyclic Compounds, 1-RingProstaglandin E synthase
go.drugbank.com/bio_entities/BE0011075TargetHumansTerminal enzyme of the cyclooxygenase (COX)-2-mediated prostaglandin E2 (PGE2) biosynthetic pathway. Catalyzes the glutathione-dependent oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) in response to inf...
Synonyms: Microsomal glutathione S-transferase 1-like 1Aluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedAluminum zirconium octachlorohydrex gly is complex that consists of aluminum zirconium octachlorohydrate and glycine. It is an active antiperspirant agent [L2705], [L2706].
Mixtures: Ron 2Products: Old Spice GentleMan s Blend Mandarin and Musk, Old Spice GentleMan s Blend Aloe and Wild SageFlavin reductase (NADPH)
go.drugbank.com/bio_entities/BE0000595TargetEnzymeHumansfrom S-nitroso-CoA to Cys-109 and Cys-188 residues of BLVRB and from S-nitroso-BLVRB to the protein substrate (PubMed:38056462). … S-nitroso-CoA-dependent nitrosyltransferase activity is mediated via a 'ping-pong' mechanism: BLVRB first associates with both S-nitroso-CoA and protein substrate, nitric oxide group is then transferred
Synonyms: S-nitroso-CoA-assisted nitrosyltransferaseDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigationalDabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: TAFINLAR®75 MG CÁPSULAS DURAS, TAFINLAR® 50 MG CÁPSULAS DURASSpermidine and Spermine Biosynthesis
smpdb.ca/view/SMP0000445MetabolicSpermidine is subsequently processed into spermine by spermine synthase in the presence of the aminopropyl donor, S-adenosylmethioninamine. … Spermidine originates from the action of spermidine synthase, which converts the methionine derivative S-adenosylmethionine and the ornithine derivative putrescine into spermidine 5'-methylthioadenosine
Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-adenosylmethionine synthase isoform type-2Navepegritide
go.drugbank.com/drugs/DB17824ApprovedInvestigational[L56065] Navepegritide was approved by the US FDA in February 2026 for use in patients 2 years of age and older with achondroplasia with open epiphyses.[L56058,L56065] … [L56058,A275435] Navepegritide is a prodrug of active C-type natriuretic peptide (CNP) consisting of a CNP moiety transiently conjugated to two methoxy polyethylene glycol (mPEG) moieties via a proprietary