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Complement C4-A
go.drugbank.com/bio_entities/BE0004685TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2Complement C4-B
go.drugbank.com/bio_entities/BE0004686TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
go.drugbank.com/bio_entities/BE0000525TargetHumansMay play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091)
Synonyms: Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 proteinZinc transporter ZIP10
go.drugbank.com/bio_entities/BE0009884TransporterHumansPlays an important for both mature B-cell maintenance and humoral immune responses (By similarity). … When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity)
Synonyms: Zrt- and Irt-like protein 10RNA-splicing ligase RTCB
go.drugbank.com/bio_entities/BE0004442TargetHumansThese exon ends are then recognized and ligated by RTCB. … The ligation reaction, which requires guanosine triphosphate (GTP) and Mn(2+), proceeds through three metal-dependent steps.
Synonyms: RNA 2',3'-cyclic phosphate and 5'-OH ligaseThioredoxin reductase 1, cytoplasmic
go.drugbank.com/bio_entities/BE0001979TargetEnzymeHumansHomodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation.
Synonyms: Gene associated with retinoic and IFN-induced mortality 12 protein, Gene associated with retinoic and interferon-induced mortality 12 proteinNuclear receptor subfamily 1 group I member 2
go.drugbank.com/bio_entities/BE0000956TargetHumansNuclear receptor that acts as a transcription factor regulating genes involved in the metabolism and excretion of xenobiotics, drugs, and endogenous compounds. … Activated by a broad range of endogenous steroids (e.g. pregnenolone, progesterone) and xenobiotics, including the antibiotic rifampicin and certain plant-derived metabolites.
Synonyms: Steroid and xenobiotic receptorRetinol dehydrogenase 12
go.drugbank.com/bio_entities/BE0000726TargetHumansMay play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation (PubMed:19686838). … Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol (PubMed:12226107, PubMed:15865448).
Synonyms: All-trans and 9-cis retinol dehydrogenaseCytoplasmic tyrosine-protein kinase BMX
go.drugbank.com/bio_entities/BE0009416TargetHumans, cell adhesion, and apoptosis. … May also play a role in the growth and differentiation of hematopoietic cells; as well as in signal transduction in endocardial and arterial endothelial cells
Synonyms: Epithelial and endothelial tyrosine kinaseMyeloid zinc finger 1
go.drugbank.com/bio_entities/BE0013131TargetHumansBinds to target promoter DNA and functions as a transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter.
Synonyms: Zinc finger and SCAN domain-containing protein 6