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Displaying results 891 - 900 of 10000 in total
  1. Target

    Serine/threonine-protein kinase A-Raf

    go.drugbank.com/bio_entities/BE0000434
    TargetHumans

    Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2 (PubMed:36402789)

    Polypeptides: Serine/threonine-protein kinase A-RafSynonyms: Proto-oncogene A-Raf, Proto-oncogene A-Raf-1
  2. Target

    Coenzyme A biosynthesis bifunctional protein CoaBC

    go.drugbank.com/bio_entities/BE0002020
    TargetEscherichia coli (strain K12)

    Catalyzes two sequential steps in the biosynthesis of coenzyme A.

    Polypeptides: Coenzyme A biosynthesis bifunctional protein CoaBC
  3. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  4. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    PPIases accelerate the folding of proteins (Probable). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  5. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum ...

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain
  6. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.

    Products: Enbrel Solution for Injection in a Pre-filled Pen 50mg, Enbrel Solution for Injection in a Pre-filled Syringe 50mg
  7. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.

    Products: ANGIOMAX® POLVO LIOFILIZADO PARA RECONSTRUIR A SOLUCIÓN INYECTABLE (50MG/ML), OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADET
  8. Drug

    Beta carotene

    go.drugbank.com/drugs/DB06755
    ApprovedNutraceutical

    [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed of two retinyl groups. … It is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits.[T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).

    Mixtures: Aces Formula/formule A A S, A/o-26 - CapletCategories: Vitamin A
  9. Indication

    Not a candidate for cataract surgery

    go.drugbank.com/conditions/DBCOND0135114
    Drugs: Pirenoxine
    Synonyms: Not a candidate for cataract surgery
  10. Indication

    Insufficient response to a previous treatment

    go.drugbank.com/conditions/DBCOND0112723
    Drugs: Avatrombopag · Eltrombopag · Fluoxetine · Fostamatinib · Nelarabine · Rilzabrutinib
    Synonyms: Insufficient response to a previous treatment