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Protein-arginine deiminase type-1
go.drugbank.com/bio_entities/BE0002314TargetHumansCatalyzes the deimination of arginine residues of proteins
Synonyms: Peptidylarginine deiminase I, Protein-arginine deiminase type ILymphoma, Diffuse
go.drugbank.com/conditions/DBCOND0036855Synonyms: Non-Hodgkin lymphoma, no ICD-O subtype, Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)Cholesteryl ester transfer protein
go.drugbank.com/bio_entities/BE0003516TargetHumansInvolved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density ...
Synonyms: Lipid transfer protein IFenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIn 2006 and 2009, the FDA issued warnings that it had been detected in diet pills sold online, and imported from foreign manufacturers. … It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency.
International brands: Desobesi-MProducts: IFA-DIETY A. P.Zinc
go.drugbank.com/drugs/DB01593ApprovedInvestigationalZinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol _Zn_ [L2098]. … It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division.
Mixtures: O-Cal Prenatal Vitamin, O-Cal FA multivitaminProducts: ZINCO-K 15MG/5 ML 28 KASIK SURUP, ZINCO-K 15MG/5 ML KASIK SURUP, 20 ADETNoncanonical Wnt/Ca2+ signaling
smpdb.ca/view/SMP0468891SignalingThe Wnt/Ca²⁺ pathway is activated by the binding of the Wnt ligand to a Frizzled receptor.
3-dehydroquinate dehydratase
go.drugbank.com/bio_entities/BE0001819TargetSalmonella typhiInvolved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-d...
Synonyms: Type I DHQase, Type I dehydroquinaseImatinib
go.drugbank.com/drugs/DB00619ApprovedInvestigationalThe discovery of imatinib also established a new group of therapy called "targeted therapy", since treatment can be tailored specifically to the unique cancer genetics of each patient. … [L42220] Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA; however, its European approval has been withdrawn in October 2023.[A263036,L49746,L49751]
Synonyms: α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidideCategories: P-glycoprotein inhibitors, P-glycoprotein substratesAcute Non-Lymphocytic Leukemia
go.drugbank.com/conditions/DBCOND0038781Drugs: TioguanineSynonyms: Acute myeloid leukemia, no ICD-O subtype (morphologic abnormality), Acute myeloid leukemia, no International Classification of Diseases for Oncology subtypeCutaneous Melanoma
go.drugbank.com/conditions/DBCOND0040978Drugs: IpilimumabSynonyms: Malignant melanoma, no ICD-O subtype, Malignant melanoma, no International Classification of Diseases for Oncology subtype