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Displaying results 931 - 940 of 10000 in total
  1. Pathway

    Metabolism and Physiological Effects of O-Sulfotyrosine

    smpdb.ca/view/SMP0126811
    Metabolic

    O-Sulfotyrosine has been identified as a potential plasma biomarker of reduced kidney function in early chronic kidney disease (CKD), end stage renal disease (ESRD), and hemodialytic clearance. … Sulfation is catalyzed by tyrosylprotein sulfotransferase (TPST) in the Golgi apparatus.

    Drugs: Phenylalanine · Tyrosine · Sapropterin · Iron
  2. Pathway

    Metabolism and Physiological Effects of S-Adenosylhomocysteine

    smpdb.ca/view/SMP0127690
    Metabolic

    It is toxic to immature lymphocytes and can lead to immunosuppression. … Therefore, when present in sufficiently high levels, S-adenosylhomocysteine can act as an immunotoxin and a metabotoxin. An immunotoxin disrupts, limits the function, or destroys immune cells.

    Drugs: Ademetionine · Methionine · ATP · Potassium cation · Magnesium cation · Pyrophosphoric acid
  3. Drug

    Brompheniramine

    go.drugbank.com/drugs/DB00835
    Approved

    Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.

    Synonyms: 3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine, 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamineMixtures: Up and Up Childrens Cold and Cough, Dimetapp Liqui-gels Cap
  4. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    [L43752] Dimethyl fumarate is marketed under the brand name Tecfidera, and it was the third oral disease-modifying agent for multiple sclerosis approved by the FDA, following [fingolimod] and [teriflunomide … Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterCategories: Antineoplastic and Immunomodulating Agents
  5. Drug

    Tigecycline

    go.drugbank.com/drugs/DB00560
    ApprovedInvestigational

    Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. … It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S.

    Products: TIGESIL-LIYO 50MG IV INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,10 FLAKON, TİGELYS 50MG IV İNFÜZYONLUK ÇÖZELTİ İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 10 ADET
  6. Drug

    Aloe vera leaf

    go.drugbank.com/drugs/DB13906
    ApprovedInvestigational

    Acemannan and other modified polysaccharides are responsible in preventing suppression of contact hypersensitivity or immune suppression induced by external factors such as irradiation [A32473]. … While aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products.

    Mixtures: Glow And Shine, Mousturizing Gloves and SocksProducts: Capsulax Cap 250mg, Capsulax Capsules 250mg
  7. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    Camphor is a bicyclic monoterpene ketone found widely in plants, especially _Cinnamomum camphora_. It is used topically as a skin antipruritic and as an anti-infective agent. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]

    Mixtures: Zam-Buk Ointment, Ken- Ku Oil Cap Pancor MasCategories: Basic Lotions and Liniments, Antipruritics and Local Anesthetics
  8. Drug

    Levomenthol

    go.drugbank.com/drugs/DB00825
    ApprovedInvestigational

    Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration … Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used to relieve minor throat irritations.

    Mixtures: Ken- Ku Oil Cap Pancor Mas, Cin Cao Gao Cap Tai ChiCategories: Basic Lotions and Liniments, Herbs and Natural Products
  9. Drug

    Oxprenolol

    go.drugbank.com/drugs/DB01580
    ApprovedWithdrawn

    A beta-adrenergic antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety.

    Categories: oxprenolol and thiazides, Beta Blocking Agents and ThiazidesProducts: Trasicor Tab 20mg, Slow Trasicor Tab 160mg
  10. Drug

    Simoctocog alfa

    go.drugbank.com/drugs/DB09108
    Approved

    The harvested product is concentrated and purified by a series of chromatography steps. … plasma-derived FVIII, has been deleted and replaced by a 16 amino acid linker.

    Categories: Amino Acids, Peptides, and ProteinsProducts: NUWIQ 500 UI, NUWIQ 2000 UI