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Displaying results 951 - 960 of 10000 in total
  1. Target

    Glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0000542
    TargetHumans

    Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity)

    Synonyms: Peptidyl-cysteine S-nitrosylase GAPDH
  2. Indication

    Fabry's Disease

    go.drugbank.com/conditions/DBCOND0028300
    Drugs: Agalsidase alfa · Agalsidase beta · Migalastat · Pegunigalsidase alfa
    Synonyms: Fabry´s Disease
  3. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine]. … [A190273] The most popular of the third generation dihydropyridines is [amlodipine].[A190273] Nifedipine was granted FDA approval on 31 December 1981.[L11383]

    Synonyms: 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylesterMixtures: NIF TEN 50, NIF-TEN CAPSULE
  4. Drug

    Colistimethate

    go.drugbank.com/drugs/DB01111
    ApprovedInvestigationalVet approved

    Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa. … Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms.

    Products: COLIS-TEK, KOLİSTİPOL 4.500.000 IU IM/IV ENJEKSİYON VE İNHALASYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ 1 FLAKON VE 1 AMPUL
  5. Indication

    Menière's Disease

    go.drugbank.com/conditions/DBCOND0066647
    Drugs: Betahistine · Dimenhydrinate · Diphenidol · Levosulpiride · Pyridoxine · Streptomycin +1 more
    Synonyms: Meniere s Disease
  6. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0009225
    TargetPlasmodium falciparum (isolate 3D7)

    Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  7. Drug

    Tilmicosin

    go.drugbank.com/drugs/DB11471
    InvestigationalVet approved

    Tilmicosin is a macrolide antibiotic. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with _Mannheimia haemolytica_.

    Categories: P-glycoprotein substratesProducts: TP-TILMIPHOS 500MG/G POWDER, TP-Mecotil 300 Sol Tilmicosin Phosphate 300mg/ml Solution
  8. Target

    Maleylacetoacetate isomerase

    go.drugbank.com/bio_entities/BE0000819
    TargetEnzymeHumans

    Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Also has low glutathione peroxidase activity with T-butyl and...

    Synonyms: Glutathione S-transferase zeta 1
  9. Target

    Adenosylhomocysteinase

    go.drugbank.com/bio_entities/BE0003776
    TargetMycobacterium tuberculosis

    May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

    Synonyms: S-adenosyl-L-homocysteine hydrolase
  10. Target

    Adenosine deaminase

    go.drugbank.com/bio_entities/BE0009226
    TargetPlasmodium falciparum (isolate 3D7)

    Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741, PubMed:31002765). Unlike mammalian adenosine deaminases, also catalyzes the deamination of 5'-methylthioadenosine (MTA), a by-product of polyamine bio...

    Synonyms: S-methyl-5'-thioadenosine deaminase