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Salicylate-Sodium NSAID Action Pathway
smpdb.ca/view/SMP0124630Drug actionSalicylate-sodium is an NSAID which possesses anti-inflammatory, analgesic and antipyretic activity. It targets the prostaglandin G/H synthase-1 (COX-1) and prostaglandin G/H synthase-2 (COX-2) in the cyclooxygenase pathway. The cyclooxy...
Avobenzone Predicted Metabolism Pathway
smpdb.ca/view/SMP0174515MetabolicMetabolites of Avobenzone are predicted with biotransformer.
Camphor Predicted Metabolism Pathway
smpdb.ca/view/SMP0174685MetabolicMetabolites of Camphor are predicted with biotransformer.
Lidocaine (Local Anaesthetic) Action Pathway
smpdb.ca/view/SMP0000398Drug actionLidocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Lidocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated...
Salicylate-Sodium Action Pathway
smpdb.ca/view/SMP0000708Drug actionSalicylate-sodium (also named salsonin or clin) is a nonsteroidal anti-inflammatory drug (NSAID). It can be used for relieving pain and reducing fever. Salicylate-sodium can block prostaglandin synthesis by the action of inhibition of pr...
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Salicylic acid +5 moreSalicylic Acid COX Action Pathway
smpdb.ca/view/SMP0124590Drug actionSalicylic acid is an acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Salicylate's use in rheumatic diseases is due to it's analgesic and anti-inflammatory activity. It targets the prostaglandin G/H synt...
Synthetic camphor Predicted Metabolism Pathway
smpdb.ca/view/SMP0174692MetabolicMetabolites of Synthetic camphor are predicted with biotransformer.
Benzethonium Predicted Metabolism Pathway
smpdb.ca/view/SMP0174874MetabolicMetabolites of Benzethonium are predicted with biotransformer.
Lidocaine (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000328Drug actionThis pathway illustrates the lidocaine targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...
Lidocaine (Local Anaesthetic) Metabolism Pathway
smpdb.ca/view/SMP0000620Drug metabolismLidocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Lidocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated...