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Displaying results 1 - 10 of 115 in total
  1. Drug

    Sodium bicarbonate

    go.drugbank.com/drugs/DB01390
    ApprovedInvestigational

    Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.

    Synonyms: Sodium bicarbonate, Bicarbonate of sodaMixtures: Polyethylene Glycol-3350, Sodium Chloride, Potassium Chloride and Sodium Bicarbonate, PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride
  2. Drug

    Sodium chloride

    go.drugbank.com/drugs/DB09153
    ApprovedInvestigationalVet approved

    Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. … Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

    Synonyms: Sodium chloride, Sodium-chlorideMixtures: PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride, PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride
  3. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release

    Synonyms: Chloride of potash, Potassium chlorideMixtures: PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride, PEG-3350, sodium chloride, sodium bicarbonate and potassium chloride
  4. Drug

    Ammonium chloride

    go.drugbank.com/drugs/DB06767
    ApprovedInvestigationalVet approved

    Ammonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.

    Synonyms: Ammonium chloride, Chlorid ammoniaMixtures: Cough and Allergy Syrup With Codeine
  5. Drug

    Magnesium chloride

    go.drugbank.com/drugs/DB09407
    ApprovedInvestigational

    Magnesium chloride salts are highly soluble in water and the hydrated form of magnesium chloride can be extracted from brine or sea water.

    Synonyms: Magnesium chloride, Anhydrous magnesium chlorideSalts: Magnesium chloride hydrate, Magnesium chloride hexahydrate
  6. Drug

    Calcium chloride

    go.drugbank.com/drugs/DB01164
    ApprovedInvestigational

    Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent. … It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement.

    Synonyms: calcium(2+) chloride, Calcium chloride anhydrousSalts: Calcium chloride dihydrate, Calcium chloride hexahydrate
  7. Drug

    Chlorothiazide

    go.drugbank.com/drugs/DB00880
    ApprovedInvestigationalVet approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)

    Salts: Chlorothiazide sodiumCategories: Sodium Chloride Symporter Inhibitors, chlorothiazide and potassium
  8. Drug

    Acetazolamide

    go.drugbank.com/drugs/DB00819
    ApprovedInvestigationalVet approved

    Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

    Salts: Acetazolamide sodiumCategories: Antiglaucoma Preparations and Miotics, Genito Urinary System and Sex Hormones
  9. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    ApprovedInvestigational

    Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass [L1801]. Docusate can be orally or rectally administered. … Recently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912].

    Salts: Docusate sodiumMixtures: Senna and Docusate Sodium, Senna and Docusate Sodium
  10. Target

    Sodium-driven chloride bicarbonate exchanger

    go.drugbank.com/bio_entities/BE0004683
    TransporterHumans

    Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride (By similarity). … Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange

    Polypeptides: Sodium-driven chloride bicarbonate exchangerFunction: sodium,bicarbonate