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Kidney Function- Proximal Convoluted Tubule
smpdb.ca/view/SMP0121001PhysiologicalSodium and bicarbonate (hydrogen carbonate) are transported by a co-transporter that is responsible for the majority of sodium reabsorption. … The proximal convoluted tubule is part of the nephron between the Bowman's capsule and the loop of Henle. The proximal convoluted tubule functions to reabsorb sodium, water, and other ions.
Enzymes: Sodium- and chloride-dependent transporter XTRP3, Electrogenic sodium bicarbonate cotransporter 1Omeprazole Action Pathway
smpdb.ca/view/SMP0122674Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Pantoprazole Action Pathway
smpdb.ca/view/SMP0123293Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Rabeprazole Antacid Action Pathway
smpdb.ca/view/SMP0123294Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Esomeprazole Action Pathway
smpdb.ca/view/SMP0123196Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Kidney Function
smpdb.ca/view/SMP0000483PhysiologicalThe early proximal tubule is where glucose, amino acids, sodium, chlorine, phosphate, bicarbonate, and water are reabsorbed. … Blood pressure is regulated by the hormones angiotensin II and aldosterone, which increases sodium chloride reabsorption.
Enzymes: Sodium- and chloride-dependent transporter XTRP3, Chloride channel protein ClC-KaLansoprazole Action Pathway
smpdb.ca/view/SMP0123261Drug actionThe bicarbonate ions go into the blood via the chloride anion exchanger on the basolateral membrane which exchanges the hydrogen bicarbonate for Cl- ions. … In parietal cells, carbonic anhydrase converts water and carbon dioxide to hydrogen bicarbonate ions and H+.
Enzymes: Chloride anion exchanger, Sodium/potassium-transporting ATPase subunit alpha-1Heroin Action Pathway
smpdb.ca/view/SMP0000407Drug actionThey are beta-endorphin, dynorphin, leu-enkephalin, and met-enkephalin. … Endorphins are regularly released in the brain and nerves, attenuating pain.
Enzymes: Sodium channel subunit beta-1, Sodium-dependent serotonin transporterGastric Acid Production
smpdb.ca/view/SMP0000589PhysiologicalHowever, it is also constituted of potassium chloride (KCl) and sodium chloride (NaCl). … a bicarbonate ion and a hydrogen ion.
Enzymes: Chloride intracellular channel protein 2Omeprazole Action Pathway (old)
smpdb.ca/view/SMP0000226Drug actionLosec and Zegerid, is a proton pump inhibitor (PPI) class drug that suppresses the final step in gastric acid production, and was the first proton pump inhibitor to e developed. … In this pathway, omeprazole is taken orally and is oxidized in the stomach to form the active metabolite of omeprazole.
Enzymes: Chloride intracellular channel protein 2