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Tripeptidyl-peptidase 1
go.drugbank.com/bio_entities/BE0011158TargetHumansLysosomal serine protease with tripeptidyl-peptidase I activity (PubMed:11054422, PubMed:19038966, PubMed:19038967). … May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases (PubMed:11054422, PubMed:19038966, PubMed:19038967).
Polypeptides: Tripeptidyl-peptidase 1Synonyms: Tripeptidyl-peptidase I, Tripeptidyl aminopeptidaseProlyl tripeptidyl peptidase
go.drugbank.com/bio_entities/BE0004097TargetPorphyromonas gingivalis (strain ATCC BAA-308 / W83)Releases tripeptides from the free amino terminus of proteins. Has a requirement for Pro in the P1 position, but is inactivated by Pro in the P1' position.
Polypeptides: Prolyl tripeptidyl peptidaseSynonyms: Prolyl tripeptidyl peptidase A, Prolyl tripeptidyl peptidase 81.8 kDa formLeukotriene A-4 hydrolase
go.drugbank.com/bio_entities/BE0001680TargetHumansAlso has aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides (PubMed:18804029, PubMed:20813919). … In addition to its pro-inflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro
Synonyms: Tripeptide aminopeptidase LTA4HUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
go.drugbank.com/bio_entities/BE0003765TargetStreptococcus pneumoniae (strain ATCC BAA-255 / R6)Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
Polypeptides: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligaseUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
go.drugbank.com/bio_entities/BE0001538TargetEscherichia coli (strain K12)Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Is also able to use many meso-diaminopimelate analo...
Synonyms: UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetaseBeta-Ala-Xaa dipeptidase
go.drugbank.com/bio_entities/BE0001606TargetLactobacillus delbrueckii subsp. lactisTo a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the removal of the N-terminal amino acid from a few distinct tripeptides.
Integrin beta-7
go.drugbank.com/bio_entities/BE0003414TargetHumansInteractions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin (Probable). Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin (PubMed:10837471)
Solute carrier family 15 member 1
go.drugbank.com/bio_entities/BE0001018TransporterTargetHumansPrimarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen (By similarity).
Periplasmic oligopeptide-binding protein OppA
go.drugbank.com/bio_entities/BE0003820TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Part of the ABC transporter complex OppABCDF involved in the uptake of oligopeptides, including the cell wall murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate (PubMed:2821267, PubMed:3301822
Solute carrier family 15 member 2
go.drugbank.com/bio_entities/BE0001134TransporterTargetHumansIn kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate (PubMed:7756356).