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Displaying results 1 - 10 of 33 in total
  1. Target

    Very low-density lipoprotein receptor

    go.drugbank.com/bio_entities/BE0004020
    TargetCarrierHumans

    Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. Also binds to a wide range of other molecules including Reelin/RELN or apolipop...

    Polypeptides: Very low-density lipoprotein receptor
  2. Target

    Low-density lipoprotein receptor

    go.drugbank.com/bio_entities/BE0000499
    TargetCarrierHumans

    Binds low density lipoprotein /LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis.

    Polypeptides: Low-density lipoprotein receptor
  3. Target

    Low affinity immunoglobulin epsilon Fc receptor

    go.drugbank.com/bio_entities/BE0003465
    TargetHumans

    Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells.

    Polypeptides: Low affinity immunoglobulin epsilon Fc receptor
  4. Target

    Low-density lipoprotein receptor-related protein 2

    go.drugbank.com/bio_entities/BE0000942
    TargetTransporterHumans

    Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and poly...

    Polypeptides: Low-density lipoprotein receptor-related protein 2
  5. Target

    Low molecular weight phosphotyrosine protein phosphatase

    go.drugbank.com/bio_entities/BE0003786
    TargetHumans

    Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2

    Polypeptides: Low molecular weight phosphotyrosine protein phosphataseSynonyms: Low molecular weight cytosolic acid phosphatase
  6. Target

    Low affinity immunoglobulin gamma Fc region receptor III-B

    go.drugbank.com/bio_entities/BE0000901
    TargetHumans

    Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis.

    Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-B
  7. Target

    Low affinity immunoglobulin gamma Fc region receptor II-b

    go.drugbank.com/bio_entities/BE0002099
    TargetHumans

    Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.

    Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-b
  8. Target

    Low-density lipoprotein receptor-related protein 6

    go.drugbank.com/bio_entities/BE0012061
    TargetHumans

    Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes (PubMed:11357136, PubMed:11448771, PubMed:15778503, PubMed:1634101...

    Polypeptides: Low-density lipoprotein receptor-related protein 6
  9. Target

    Low affinity immunoglobulin gamma Fc region receptor II-a

    go.drugbank.com/bio_entities/BE0002098
    TargetHumans

    Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens

    Polypeptides: Low affinity immunoglobulin gamma Fc region receptor II-a
  10. Target

    Low affinity immunoglobulin gamma Fc region receptor III-A

    go.drugbank.com/bio_entities/BE0002097
    TargetHumans

    Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG). Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-d...

    Polypeptides: Low affinity immunoglobulin gamma Fc region receptor III-A