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Displaying results 1 - 10 of 14 in total
  1. Target

    Estradiol 17-beta-dehydrogenase 11

    go.drugbank.com/bio_entities/BE0002840
    TargetHumans

    Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/...

    Polypeptides: Estradiol 17-beta-dehydrogenase 11Function: estradiol 17-beta-dehydrogenase [NAD(P)+] activity
  2. Target

    Estrogen receptor

    go.drugbank.com/bio_entities/BE0000123
    TargetHumans

    Maintains neuronal survival in response to ischemic reperfusion injury when in the presence of circulating estradiol (17-beta-estradiol/E2) (By similarity)

    Synonyms: Estradiol receptor
  3. Target

    17-beta-hydroxysteroid dehydrogenase type 3

    go.drugbank.com/bio_entities/BE0000336
    TargetEnzymeHumans

    Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids (PubMed:16216911, PubMed:23856005, PubMed:26545797, PubMed:27927697, PubMed:8075637). Favors the reduction of androstenedione to testosterone (PubMed:16216911, PubMed:2...

    Synonyms: Estradiol 17-beta-dehydrogenase 2Function: estradiol 17-beta-dehydrogenase [NAD(P)+] activity
  4. Target

    Sex hormone-binding globulin

    go.drugbank.com/bio_entities/BE0000685
    CarrierTargetHumans

    Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration

    Synonyms: Testosterone-estradiol-binding globulin
  5. Target

    Dehydrogenase/reductase SDR family member 11

    go.drugbank.com/bio_entities/BE0003011
    TargetHumans

    Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3beta-...

    Synonyms: Estradiol 17-beta-dehydrogenase
  6. Target

    Aminoglycoside nucleotidyltransferase (4')

    go.drugbank.com/bio_entities/BE0003547
    EnzymeStaphylococcus aureus

    Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.

    Synonyms: kan
  7. Target

    Estrogen receptor

    go.drugbank.com/bio_entities/BE0010245
    TargetHumans

    Maintains neuronal survival in response to ischemic reperfusion injury when in the presence of circulating estradiol (17-beta-estradiol/E2) (By similarity)

    Synonyms: Estradiol receptor
  8. Target

    Very-long-chain 3-oxoacyl-CoA reductase

    go.drugbank.com/bio_entities/BE0014905
    EnzymeHumans

    May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation

    Synonyms: Estradiol 17-beta-dehydrogenase 12
  9. Target

    3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

    go.drugbank.com/bio_entities/BE0000184
    TargetHumans

    Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:12574203, PubMed:12732193, PubMed:19772289).

    Synonyms: Estradiol 17-beta-dehydrogenase 7
  10. Target

    17-beta-hydroxysteroid dehydrogenase type 1

    go.drugbank.com/bio_entities/BE0000194
    TargetEnzymeHumans

    Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:8994190). Also has 20-alpha-HSD activity. Uses preferentially NADH

    Synonyms: Estradiol 17-beta-dehydrogenase 1