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Displaying results 1 - 10 of 50 in total
  1. Target

    Na(+)/citrate cotransporter

    go.drugbank.com/bio_entities/BE0008677
    TransporterHumans

    Transports citrate into the cell in a Na(+)-dependent manner, recognizing the trivalent form of citrate (physiological pH) rather than the divalent form (PubMed:12445824, PubMed:12826022, PubMed:26324167 … The stoichiometry is probably 4 Na(+) for each carboxylate, irrespective of whether the translocated substrate is divalent or trivalent, rendering the process electrogenic (PubMed:12445824, PubMed:12826022

    Polypeptides: Na(+)/citrate cotransporter
  2. Target

    Na(+)/dicarboxylate cotransporter 3

    go.drugbank.com/bio_entities/BE0000611
    TransporterHumans

    Can transport citrate in a Na(+)-dependent manner, recognizing the divalent form of citrate rather than the trivalent form which is normally found in blood (PubMed:10794676). … Transports the dicarboxylate into the cell with a probable stoichiometry of 3 Na(+) for 1 divalent dicarboxylate, rendering the process electrogenic (PubMed:10794676, PubMed:10992006).

    Polypeptides: Na(+)/dicarboxylate cotransporter 3Synonyms: Na(+)-coupled carboxylate transporter 3
  3. Target

    Na(+):neurotransmitter symporter (Snf family)

    go.drugbank.com/bio_entities/BE0003930
    TargetAquifex aeolicus (strain VF5)

    Polypeptides: Na(+):neurotransmitter symporter (Snf family)
  4. Target

    Solute carrier family 12 member 3

    go.drugbank.com/bio_entities/BE0000419
    TargetTransporterHumans

    Electroneutral sodium and chloride ion cotransporter, which acts as a key mediator of sodium and chloride reabsorption in kidney distal convoluted tubules (PubMed:18270262, PubMed:21613606, PubMed:22009145, PubMed:36351028, PubMed:367928...

    Synonyms: Na-Cl symporter, Na-Cl cotransporter
  5. Target

    Solute carrier family 13 member 4

    go.drugbank.com/bio_entities/BE0010199
    TransporterHumans

    Sodium:sulfate symporter that mediates sulfate reabsorption in the high endothelial venules (HEV)

    Synonyms: Na(+)/sulfate cotransporter SUT-1
  6. Target

    Solute carrier family 12 member 2

    go.drugbank.com/bio_entities/BE0000281
    TargetTransporterHumans

    Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:16669787, PubMed:32081947, PubMed:32294086, PubMed:33597714, PubMed:35585053, PubMed:36239040...

    Synonyms: Na-K-2Cl cotransporter 1, Basolateral Na-K-Cl symporter
  7. Target

    Sodium/potassium-transporting ATPase subunit alpha-3

    go.drugbank.com/bio_entities/BE0005047
    TargetTransporterHumans

    Neuron-specific alpha catalytic component of the Na(+)/K(+)-transporting ATPase, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane (PubMed … Transports 3 Na(+) ions out of the cell and 2 K(+) ions into the cell for each ATP hydrolyze against their electrochemical gradients to maintain ion concentration gradients across the membranes (By similarity

    Synonyms: Na(+)/K(+) ATPase alpha-3 subunit, Na(+)/K(+) ATPase alpha(III) subunit
  8. Target

    Solute carrier family 12 member 1

    go.drugbank.com/bio_entities/BE0000502
    TargetTransporterHumans

    Renal sodium, potassium and chloride non-electrogenic ion symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation (PubMed:21...

    Synonyms: Na-K-2Cl cotransporter 2, Kidney-specific Na-K-Cl symporter
  9. Target

    Sodium/iodide cotransporter

    go.drugbank.com/bio_entities/BE0009346
    TargetTransporterHumans

    Sodium:iodide symporter that mediates the transport of iodide into the thyroid gland (PubMed:12488351, PubMed:18372236, PubMed:18708479, PubMed:20797386, PubMed:31310151, PubMed:32084174, PubMed:8806637, PubMed:9329364). Can also mediate...

    Synonyms: Na(+)/I(-) symporter, Na(+)/I(-) cotransporter
  10. Target

    Sodium/hydrogen exchanger 1

    go.drugbank.com/bio_entities/BE0000752
    TargetTransporterHumans

    Electroneutral Na(+) /H(+) antiporter that extrudes Na(+) in exchange for external protons driven by the inward sodium ion chemical gradient, protecting cells from acidification that occurs from metabolism … Exchanges intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry (By similarity).

    Synonyms: Na(+)/H(+) exchanger 1, Na(+)/H(+) antiporter, amiloride-sensitive