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  1. Pathway

    Ethanol Glycine Agonist Action Pathway

    smpdb.ca/view/SMP0126452
    Drug action

    This causes an influx of chlorine ions which hyperpolarizes the neuron. Glycine receptors are present mainly in the spinal cord and brain stem where they control motor function. … The main effects are seen by the binding to GABA receptors, glycine receptors, and glutamate receptors. Ethanol agonizes glycine receptors, where glycine binds to the alpha subunit.

    Drugs: Glycine · Ethanol · Calcium
    Enzymes: Vesicular inhibitory amino acid transporter
  2. Pathway

    Disulfiram Action Pathway

    smpdb.ca/view/SMP0000429
    Drug action

    Disulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism. … This causes more dopamine to accumulate in the axon terminal and more dopamine is released.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 more
    Enzymes: Aromatic-L-amino-acid decarboxylase, Tyrosine aminotransferase
  3. Indication

    Skin Irritation

    go.drugbank.com/conditions/DBCOND0062614
    Drugs: Aluminum hydroxide · Ammonia · Benzocaine · Benzyl alcohol · Camphor · Cetrimonium +19 more