Search

Displaying results 1 - 10 of 87 in total
  1. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    into active metabolites: (+)-tramadol and its primary metabolite (+)-O-desmethyl-tramadol (M1) are agonists of the μ opioid receptor while (+)-tramadol inhibits serotonin reuptake and (-)-tramadol inhibits … [A182300] Similar to other opioid medications, tramadol poses a risk for development of tolerance, dependence and abuse.

    Synonyms: Tramadol, TramadolumInternational brands: Tramal
  2. Pathway

    Tramadol Metabolism Pathway

    smpdb.ca/view/SMP0000637
    Drug metabolism

    Tramadol (also named Ultram) is a class of opioid pain medication that used for treating pain. Metabolism of tramadol mainly happened in liver cell. … The O-demethylation of tramadol is catalyzed by the cytochrome CYP2D6 to form O-Desmethyltramadol, which further metabolized to O-Desmethyltramadol glucuronide through UDP-glucuronosyltransferase 2B7 and

    Drugs: NADH · ATP · Tramadol · Mesoheme · Uridine-5'-Diphosphate · Formaldehyde
  3. Pathway

    Tramadol Action Action Pathway

    smpdb.ca/view/SMP0000671
    Drug action

    Tramadol is an analgesic drug consisting of two enantiomer forms (+)-Tramadol and (-)-Tramadol. … (-)-Tramadol inhibits norepinephrine reuptake in the central nervous system.

    Drugs: ATP · Tramadol · Norepinephrine · Dopamine · Potassium cation · Calcium
  4. Pathway

    Tramadol Opioid Agonist Action Pathway

    smpdb.ca/view/SMP0125025
    Drug action

    Tramadol binds to mu opioid receptors, stimulating the exchange of GTP for GDP on the G-protein complex. … Tramadol is a centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults.

    Drugs: ATP · Tramadol · Calcium · Magnesium cation · Cyclic adenosine monophosphate · gamma-Aminobutyric acid +2 more
  5. Drug

    Trazodone

    go.drugbank.com/drugs/DB00656
    ApprovedInvestigational

    Trazodone is triazolopyridine derivative from the serotonin receptor antagonists and reuptake inhibitors (SARIs) class of antidepressants. It is used in adults and has been shown to be comparable in efficacy to other drugs such as tricyc...

    Products: TRAMADOL GOTAS 100 MG/ML, TRAMADOL GOTASX100 MG/ML
  6. Drug

    Copper

    go.drugbank.com/drugs/DB09130
    ApprovedInvestigational

    Copper is commonly used in contraceptive intrauterine devices (IUD) [L801]. … Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label].

    Synonyms: cobre, CopperMixtures: Complex, Kamu Jay Multi Complex Tab
  7. Drug

    Prochlorperazine

    go.drugbank.com/drugs/DB00433
    ApprovedInvestigationalVet approved

    Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such a...

    Products: Compro
  8. Drug

    Copper oxodotreotide Cu-64

    go.drugbank.com/drugs/DB15873
    Approved

    [A220348] Further studies should be performed to compare the two tracers. … Copper Cu 64 dotatate is a newly approved Cu labeled somatostatin analog and has several advantages over <sup>68</sup>Ga-labeled somatostatin analogs for positron emission tomography (PET).

    Synonyms: Copper 64-DOTA-tate, Copper Cu-64 dotatateCategories: Copper Radioisotopes
  9. Drug

    Copper histidinate

    go.drugbank.com/drugs/DB32041
    Approved

    [A275383] Copper histidinate is a subcutaneously-administered copper-histidine complex that allows for copper supplementation in patients with defective ATP7A transporters. … in severe systemic copper deficiency.

    Synonyms: Copper histidine, Copper histidinate
  10. Drug

    Copper gluconate

    go.drugbank.com/drugs/DB11246
    ApprovedInvestigational

    Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. … According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005

    Synonyms: Copper gluconateProducts: Copper (gluconate) 2 Mg Tablets