Displaying drugs 226 - 250 of 11636 in total
Imipenem
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Description: … first approved by the FDA in November 1985 as the combination product Primaxin marketed by Merck & Co ... Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative ... for having greater activity against Gram negative bacteria, and the newer [ertapenem] which exhibits a …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Mixtures name: … IMIPENEM/CILASTATINA POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... ARZOMEBA PISA 500MG/500MG (IMIPENEM+CILASTATINA) POLVO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Cocaine
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of...
Approved
Illicit
Matched Description: … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in ... It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse …
Bepridil
A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. The drug produces significant coronary vasodilation and modest peripheral effects. It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. It is no longer marketed in the United States, as it has been implicated in causing...
Approved
Withdrawn
Matched Description: … A long-acting, non selective, calcium channel blocker with significant anti-anginal activity. ... It has antihypertensive and selective anti-arrhythmia activities and acts as a calmodulin antagonist. …
Sodium carbonate
Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Approved
Matched Description: … As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid. …
Matched Mixtures name: … GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Mixtures name: … GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Procaine benzylpenicillin
Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It...
Approved
Vet approved
Matched Description: … It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin ... This drug is used where prolonged exposure to benzylpenicillin at a low concentration is required. ... Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many …
Matched Mixtures name: … Bicillin A-P Injection Pws …
Matched Mixtures name: … Bicillin A-P Injection Pws …
Abatacept
Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes ... [L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight ... of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. …
Alternaria alternata
Alternaria alternata is a fungus which can provoke allergic reactions. Alternaria alternata extract is used in allergenic testing.
Approved
Matched Description: … Alternaria alternata is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Mold Mix A ... Mold Mix A …
Matched Mixtures name: … Mold Mix A ... Mold Mix A …
Sotagliflozin
Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind, which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 diabetes mellitus (T1DM) and a BMI ≥27 kg/m2. Its potency in inhibiting SGLT2 is similar...
Approved
Investigational
Matched Description: … [L39734] A similar approval has also been sought in the US, but the FDA has since published a proposal ... Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind,[A244499] which is approved ... combination with insulin, to improve glycemic control in patients with type 1 diabetes mellitus (T1DM) and a …
Tolcapone
Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Approved
Withdrawn
Matched Description: … Tolcapone is associated with a risk of hepatotoxicity. ... It is a yellow, odorless, non-hygroscopic, crystalline compound. ... Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). …
Oxyquinoline
Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and pesticide properties. It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products.
Approved
Vet approved
Matched Description: … Oxyquinoline is a heterocyclic phenol and derivative of quinoline with antiseptic, disinfectant, and ... It is used as a stabilizer for hydrogen peroxide, where it is sometimes added in cosmetic products. …
Trichloroethylene
Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic. Environmental exposure,...
Approved
Matched Description: … It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic ... Trichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the ... Environmental exposure, particularly groundwater and drinking water contamination from industrial discharge, is a …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
p-Phenylenediamine
Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …
Imipramine
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … In depressed individuals, imipramine exerts a positive effect on mood. ... Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. ... They contain a tricyclic ring system with an alkyl amine substituent on the central ring. …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2B6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Propofol
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness,...
Approved
Investigational
Vet approved
Matched Description: … administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a …
Isoniazid
Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.
Approved
Investigational
Matched Description: … Antibacterial agent used primarily as a tuberculostatic. …
Dimethyl sulfoxide
A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including...
Approved
Vet approved
Matched Description: … A highly polar organic liquid, that is used widely as a chemical solvent. ... Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application ... Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Cimetidine
A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … Cimetidine has a range of pharmacological actions. ... A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. …
Methocarbamol
Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated pain.[A178441,A178450] It is a guaiacol glyceryl ether. Methocarbamol tablets and intramuscular injections are prescription medicines indicated in the United States as an adjunct to rest, physical therapy, and other measures for the relief of...
Approved
Vet approved
Matched Description: … [A178441,A178450] It is a guaiacol glyceryl ether. ... Methocarbamol was developed in the early 1950s as a treatment for muscle spasticity and the associated ... [Label,L6268] In Canada, methocarbamol can be sold as an over the counter oral medicine at a lower dose …
Matched Mixtures name: … SINAXAR ® A TABLETAS ... SINAXAR ® A TABLETAS …
Matched Mixtures name: … SINAXAR ® A TABLETAS ... SINAXAR ® A TABLETAS …
Flurbiprofen
Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis....
Approved
Investigational
Matched Description: … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic …
Matched Products: … STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON …
Matched Products: … STREPSILS INTENSIVE SOLUCION EN SPRAY SABOR A MIEL Y LIMON …
Rotavirus vaccine
Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1116] Rotarix is a live attenuated vaccine containing the 89-12 human strain. …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Matched Salts name: … Human Rotavirus A type G1P(8) strain RIX4414 live antigen ... Human Rotavirus A type G1P7(5) strain WI79 live antigen ... Human Rotavirus A type G2P7(5) strain SC2 live antigen ... Human Rotavirus A type G4P7(5) strain BRB live antigen ... Human Rotavirus A type G3P7(5) strain WI78 live antigen …
Emicizumab
Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable...
Approved
Investigational
Matched Description: … Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation ... Ltd. and co-developed with Roche and Genentech.[L1015] ... [A31279, L1016] It was created by Chugai Pharmaceuticals Co. …
Procarbazine
An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Antithrombin III human
A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Approved
Matched Description: … It is a member of the serpin superfamily. ... A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and …
Tenoxicam
Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Approved
Glycerol phenylbutyrate
Glycerol phenylbutyrate is a nitrogen-binding agent. Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol backbone. FDA approved on February 1, 2013.
Approved
Matched Description: … Chemically, it is a triglyceride in which three molecules of phenylbutyrate are linked to a glycerol ... Glycerol phenylbutyrate is a nitrogen-binding agent. …
Displaying drugs 226 - 250 of 11636 in total