Displaying drugs 3376 - 3400 of 11866 in total
Bismuth subsalicylate
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that ... ], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ for ... [L32318] Bismuth subsalicylate is a component of HELIDAC Therapy (bismuth subsalicylate, [metronidazole …
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Description: … [A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather …
Lusutrombopag
Lusutrombopag is an orally bioavailable thrombopoietin receptor (TPOR) agonist developed by Shionogi & Company (Osaka, Japan). TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote megakaryocyte proliferation and differentiation, and affect other hematopoietic lineages as well, including erythroid, granulocytic and lymphoid lineages...
Approved
Investigational
Matched Description: … TPOR is a regulatory target site for endogenous thrombopoietin, which acts as a primary cytokine to promote ... Thrombocytopenia, which indicates abnormally low levels of platelets, is a common complication related ... count <50,000/μL), creates challenges to patients requiring invasive medical procedures where there is a …
Ditiocarb zinc
Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Description: … It also a dermatological sensitizer and allergen. ... Sensitivity to ditiocarb zinc may be identified with a clinical patch test. ... Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Verteporfin
Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers: CL-315555 and CL-315585. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red...
Approved
Investigational
Matched Description: … Verteporfin, marketed as Visudyne, is a benzoporphyrin derivative comprising a 50:50 mixture of two isomers ... It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form ... Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a …
Esterified estrogens
Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. ... Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of menopause …
Methyl nicotinate
Methyl nicotinate is the methyl ester of DB00627 that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. For veterinary purposes, methyl nicotinate is used to...
Approved
Matched Description: … Methyl nicotinate is the methyl ester of [DB00627] that is used as an active ingredient as a rubefacient ... The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation. …
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Rhizopus arrhizus var. arrhizus
Rhizopus arrhizus var. arrhizus is a fungus which can provoke allergic reactions. Rhizopus arrhizus var. arrhizus extract is used in allergenic testing.
Approved
Matched Description: … Rhizopus arrhizus var. arrhizus is a fungus which can provoke allergic reactions. …
Anacaulase
Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (Ananas comosus [L.] Merr.). It is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked...
Approved
Investigational
Matched Description: … Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple ... Removing eschar (a process also known as debridement) through surgical procedures can lead to significant …
Methscopolamine bromide
A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
Approved
Matched Description: … A muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors. …
Bacillus calmette-guerin substrain russian BCG-I live antigen
Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into the bladder for the adjuvant treatment of papillary urothelial cell carcinoma of the bladder. Live BCG vaccines administered intravesically have been a gold standard therapy in the adjuvant treatment of non-muscle-invasive bladder cancers for decades, used...
Approved
Matched Description: … Bacillus Calmette-Guerin (BCG) substrain Russian BCG-I is a live BCG vaccine administered directly into ... Live BCG vaccines administered intravesically have been a gold standard therapy in the adjuvant treatment ... bladder cancers for decades,[A232264] used after tumor resection, and are thought to work by stimulating a …
Butabarbital
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other ... [A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative ... [A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital …
Anifrolumab
Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus.[A237074,L34929] The standard therapy for systemic lupus erythematosus consists of antimalarials like hydroxychloroquine, glucocorticoids like dexamethasone, and disease modifying antirheumatic drugs like methotrexate.[A237079,L34929]
Three...
Approved
Investigational
Matched Description: … Anifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody …
Odevixibat
Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC).[A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC. Previous therapies for PFIC included a bile acid sequestrant such as ursodeoxycholic...
Approved
Investigational
Matched Description: … [L34803] Previous therapies for PFIC included a bile acid sequestrant such as [ursodeoxycholic acid]. …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Orlistat
The global prevalence of obesity is increasing rapidly. Obesity-related complications lead to significant personal and economic burden by reducing quality of life and increasing the cost of healthcare. In some individuals, diet and exercise are insufficient to maintain weight loss, and pharmacological or surgical intervention is required. Orlistat is a...
Approved
Investigational
Matched Description: … It was approved by the FDA for use in combination with a reduced-calorie diet in 1999. ... [A229928]
Orlistat is a lipase inhibitor used in the treatment of obesity that works by inhibiting ... [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in …
Dihydrocodeine
Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough.
It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Description: … It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more …
Trihexyphenidyl
Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity. Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant...
Approved
Matched Description: … Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced ... [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity ... [A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment …
Golimumab
Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … The FDA label includes a black box warning of serious infections and malignancy. ... Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with ... as an adjunct to methotrexate treatment in patients with active psoriatic arthritis (PsA), (iii) as a …
Sodium camphorsulfonate
Approved
Experimental
Ferric cation
Iron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. Iron is an essential element involved in various metabolic processes, including oxygen transport, deoxyribonucleic acid (DNA) synthesis, and energy production in electron transport . Resulting from inadequate...
Approved
Matched Description: … Iron is a transition metal with a symbol Fe and atomic number 26. ... Ferric citrate (tetraferric tricitrate decahydrate) is a phosphate binder indicated for the control of …
Valine
Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Description: … It is a precursor in the penicillin biosynthetic pathway. ... Valine is a branched-chain essential amino acid that has stimulant activity. …
Voclosporin
Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a...
Approved
Investigational
Matched Description: … LN is a significant cause of renal failure, morbidity, and death in patients with SLE. ... Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus ... years of being diagnosed with SLE, 5-20% of those suffering from LN develop end-stage kidney disease, a …
Displaying drugs 3376 - 3400 of 11866 in total