Displaying drugs 3576 - 3600 of 11857 in total
Tafenoquine
Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group.[A35671, A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a substitute for primaquine that would be more effective against relapsing vivax malaria. Tafenoquine was...
Approved
Investigational
Matched Description: … Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy ... A35690] It was discovered by the scientists at the Walter Reed Army Institute of Research in 1978 as a …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha [L1874]. ... Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting ... Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses …
Iva axillaris pollen
Iva axillaris pollen is the pollen of the Iva axillaris plant. Iva axillaris pollen is mainly used in allergenic testing.
Approved
Apiospora montagnei
Apiospora montagnei is a fungus which can provoke allergic reactions. Apiospora montagnei extract is used in allergenic testing.
Approved
Matched Description: … Apiospora montagnei is a fungus which can provoke allergic reactions. …
Cyproterone acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Regdanvimab
Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding ... Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 …
Stavudine
A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Approved
Investigational
Matched Description: … A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. …
Raltitrexed
Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.
Approved
Investigational
Matched Description: … Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an …
Florbetaben F-18
Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography (PET) imaging of the brain. It is used for the non-invasive detection of the density of ß-amyloid neuritic plaques in the brain of adult patients with cognitive impairment.
Approved
Matched Description: … Florbetaben is a fluorine-18 (18F)-labeled stilbene derivative used for Positron Emission Tomography …
Deucravacitinib
Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. Unlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity to this therapeutic target.[A246938, A246943] This selectivity towards TYK2 may...
Approved
Investigational
Matched Description: … Deucravacitinib is a novel oral selective tyrosine kinase 2 (TYK2) inhibitor. ... to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a …
Pegulicianine
Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer. It is used following surgical resection of the primary tumor to detect areas of remaining cancer. Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence quencher that keeps the...
Approved
Matched Description: … Pegulicianine itself is a prodrug comprising three main fragments, one of which contains a fluorescence ... fluorescent signal that can be detected using a fluorescence imaging device. ... The _in vivo_ enzymatic cleavage of pegulicianine results in two optically active fragments that emit a …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Description: … a higher diuretic potential. ... Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from ... Furosemide has a fast onset and short duration of action and has been used safely and effectively in …
Promethazine
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171]
Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … [A189901] Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications …
Lomustine
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Prochlorperazine
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia.[label] It mainly works by depressing the chemoreceptor trigger zone and blocking...
Approved
Vet approved
Matched Description: … Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic …
Dioctyldimonium
Approved
Experimental
Magnesium Aluminum Silicate
Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite group . It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking agent, opacifying agent, viscosity-increasing agent, suspending agent, tablet and capsule disintegrant, and
tablet binder. It also...
Approved
Matched Description: … Magnesium aluminum silicate is a naturally occurring mineral obtained from silicate ores of the montmorillonite ... It is refined to a powder for use in cosmetic and pharmaceutical applications as an absorbent, anticaking ... It also has antacid properties and is used as a component of some over the counter antacid medications …
Evinacumab
Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein 3 (ANGPTL3) and the first drug of its kind. The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the regulation of lipid metabolism - which have made them desirable therapeutic targets in...
Approved
Investigational
Matched Description: … rationale for the development of a therapy targeted against ANGPTL3. ... Evinacumab is a recombinant human IgG4 monoclonal antibody targeted against angiopoietin-like protein ... The ANGPTL family of proteins serve a number of physiologic functions - including involvement in the …
Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Approved
Investigational
Matched Description: … Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B …
Zuclopenthixol
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound...
Approved
Investigational
Matched Description: … This drug is a liquid. This compound belongs to the thioxanthenes. ... derived from xanthene by replacing the oxygen atom with a sulfur atom. ... Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine …
Cetirizine
Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … One of the most common uses for this drug is for a condition called _allergic rhinitis_. …
Iobenguane sulfate I-123
Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated tissues [FDA Label].
Approved
Investigational
Matched Description: … Iobenguane sulfate I-123 is a radiopharmaceutical used in gamma-scintigraphy of adrenergically inervated …
Displaying drugs 3576 - 3600 of 11857 in total