Displaying drugs 3651 - 3675 of 11778 in total
Lanadelumab
Lanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection. It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells. It has been granted priority review, breakthrough therapy, and orphan drug designations for rare diseases based on the results of clinical...
Approved
Investigational
Matched Description: … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells ... Lanadelumab, also known as DX-2930, is a human IgG1 monoclonal antibody designed for subcutaneous self-injection …
Equine Botulinum Neurotoxin G Immune FAB2
Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype G. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes G in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin G Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin F Immune FAB2
Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype F. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin D Immune FAB2
Equine Botulinum Neurotoxin D Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype D. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes D in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin D Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Equine Botulinum Neurotoxin B Immune FAB2
Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype B. It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes B in...
Approved
Experimental
Investigational
Matched Description: … Equine Botulinum Neurotoxin B Immune FAB2 is composed of a mixture of immune globulin fragments purified …
Dronabinol
Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and...
Approved
Illicit
Matched Description: … for such a wide variety of medical conditions. ... (THCA-A) and cannabidiolic acid (CBDA), through decarboxylation reactions. ... Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary …
Tamsulosin
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common.[Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.[Label] Antagonism of these receptors leads to relaxation of smooth muscle in...
Approved
Investigational
Matched Description: … Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect …
Voxelotor
Voxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. This is a genetically inherited condition most prevalent in the Middle East, Africa, and certain parts of India. Sickle cell disease can lead to excruciating pain, stroke, infection, and various other complications arising from the...
Approved
Investigational
Matched Description: … Voxelotor is a novel hemoglobin S polymerization inhibitor for the treatment of sickle cell disease. ... This is a genetically inherited condition most prevalent in the Middle East, Africa, and certain parts ... [T734]
Voxelotor was granted accelerated FDA approval on November 25 2019, as it is likely to be a …
Zileuton
Leukotrienes are substances that induce numerous biological effects including augmentation of neutrophil and eosinophil migration, neutrophil and monocyte aggregation, leukocyte adhesion, increased capillary permeability, and smooth muscle contraction. These effects contribute to inflammation, edema, mucus secretion, and bronchoconstriction in the airways of asthmatic patients. Zileuton relieves such symptoms through its...
Approved
Investigational
Withdrawn
Allenrolfea occidentalis pollen
Allenrolfea occidentalis pollen is the pollen of the Allenrolfea occidentalis plant. Allenrolfea occidentalis pollen is mainly used in allergenic testing.
Approved
Polistes annularis venom protein
Polistes annularis venom protein is an extract of Polistes annularis venom. Polistes annularis venom protein is used in allergenic testing.
Approved
Ritonavir
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritonavir and other protease inhibitors. It is now more commonly used as a...
Approved
Investigational
Matched Description: … Any HCV/HIV-1 co-infected patients treated with ritonavir-containing combination therapies should also ... It is now more commonly used as a booster of other protease inhibitors and is available in both liquid ... HCV) infection, it is added in combination therapies indicated for the treatment of HCV infections as a …
Laurocapram
Approved
Fluvastatin
Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. ... Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol …
Propoxycaine
Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride . This drug was removed from the US market in 1996. Although no longer available in the United States, this medication was used in combination...
Approved
Matched Description: … Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration …
Toripalimab
The proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance. One mechanism by which this occurs is through the overexpression of programmed cell death ligand (PD-L1) - the binding of PD-L1 (and PD-L2) to its target receptor (PD-1) results in the...
Approved
Investigational
Matched Description: … [L48681]
Toripalimab is a selective, recombinant, humanized IgG4 monoclonal antibody targeted against …
Pemigatinib
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells. FGFRs gained attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a wide...
Approved
Investigational
Matched Description: … Pemigatinib is a small molecule kinase inhibitor with antitumour activity. ... attention as potential therapeutic targets in selected cancers, as FGFR gene alterations were observed in a ... unresectable locally advanced or metastatic cholangiocarcinoma in previously treated adult patients with a …
Human Rho(D) immune globulin
Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used to prevent the immunological condition known as Rh disease (or hemolytic disease of newborn). Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction containing antibodies to the...
Approved
Investigational
Matched Description: … Human Rho(D) immune globulin is a medicine given by intramuscular or intravenous injection that is used ... Rho (D) immune globulin is available as a sterile, lyophilized or liquid gamma globulin (IgG) fraction …
Brexpiprazole
Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. Although it is structurally similar to aripiprazole, brexpiprazole has different binding affinities for dopamine and serotonin receptors. Compared...
Approved
Investigational
Matched Description: … It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. ... Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called …
Liothyronine
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Description: … Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 ... Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine …
Enzalutamide
Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.[L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be...
Approved
Matched Description: … [A252667,A252642]
Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was ... [L40639] It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012. ... Compared to the average time of 10 to 15 years for a drug to go from pre-clinical to clinical studies …
Indium In-111 oxyquinoline
Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of autologous leukocytes. It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. Indium-111 decays by isomeric transition and electron capture to cadmium-111, emitting a gamma ray that can be detected with a gamma ray...
Approved
Matched Description: … can be detected with a gamma ray camera. ... It is composed of a 3:1 saturated complex of In-111 isotope and oxyquinoline. ... Indium In 111 oxyquinoline (oxine) is a diagnostic radiopharmaceutical intended for radiolabeling of …
Ranitidine
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to …
Displaying drugs 3651 - 3675 of 11778 in total