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Displaying drugs 951 - 975 of 15549 in total

D-alpha-Tocopherol acetate

Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … Vitamin E acetate, D- …
Matched Iupac: … (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate …
Matched Description: … indications for vitamin E use. ... who may demonstrate a genuine deficiency in vitamin E. ... males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg ( …
Matched Mixtures name: … Vitamin A C E W.niacinam.beta Car.and Min. ... Webber E Plus 3 Cap ... Iron With Vitamins C and E - Tab …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Vitamin E ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Vitamine E 800 Cap ... Vitamine E 100 Cap ... Vitamine E Cap 800iu …

Melphalan flufenamide

Melphalan flufenamide, also known as melflufen or J1, is a prodrug of melphalan.[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases. In vitro models show that melphalan is 10 to hundreds of times more potent than melphalan. The increased...
Approved
Withdrawn
Matched Iupac: … ethyl (2S)-2-[(2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanamido]-3-(4-fluorophenyl)propanoate …
Matched Description: … It has since been withdrawn from the market in the wake of the phase 3 OCEAN trial which showed a decrease ... [A230123] The increased potency makes melphalan flufenamide a treatment option for patients with relapsed ... in overall survival in comparison to standard treatment with [pomalidomide] and [dexamethasone] despite …

Methyl aminolevulinate

Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Approved
Investigational
Matched Description: … in photodynamic therapy. ... Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used …
Matched Categories: … Photosensitizing Agents for Phototherapy ... Sensitizers Used in Photodynamic/radiation Therapy …

Leucanthemum vulgare pollen

Leucanthemum vulgare pollen allergenic extract is used in allergenic testing.
Approved
Matched Description: … Leucanthemum vulgare pollen allergenic extract is used in allergenic testing. …

Posaconazole

Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Approved
Investigational
Vet approved
Matched Iupac: … )piperazin-1-yl]phenyl}-1-[(2S,3S)-2-hydroxypentan-3-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one ... 4-{4-[4-(4-{[(3R,5R)-5-(2,4-difluorophenyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]oxolan-3-yl]methoxy}phenyl …
Matched Description: … and Aspergillus species in severely immunocompromised patients. ... Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species …
Matched Categories: … Antimycotics for Systemic Use ... Antiinfectives for Systemic Use …

Polidocanol

Polidocanol is a sclerosing agent indicated to treat uncomplicated spider veins (varicose veins ≤1 mm in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity. It is marketed under the brand names Asclera and Varithena. The formula for Polidocanol has the structural...
Approved
Matched Description: … in diameter) and uncomplicated reticular veins (varicose veins 1 to 3 mm in diameter) in the lower extremity ... The formula for Polidocanol has the structural formula C12H25(OCH2CH2)nOH, a mean extent of polymerization ... (n) of approximately 9 and a mean molecular weight of approximately 600. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Sclerosing Agents for Local Injection …
Matched Products: … Aethoxysklerol 2 % - Ampullen ... ATEROSKLEROL % 2 AMPUL, 5 ADET ... VARİKANOL % 2 ENJEKSİYONLUK ÇÖZELTİ …

Technetium Tc-99m tetrofosmin

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Iupac: … bis(6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane) (⁹⁸Tc)technetium dihydrate …
Matched Description: … Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. ... The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands ... It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit which …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Olea europaea pollen

Olea europaea pollen is the pollen of the Olea europaea plant. Olea europaea pollen is mainly used in allergenic testing.
Approved
Matched Description: … Olea europaea pollen is mainly used in allergenic testing. …
Matched Mixtures name: … Western 3 Tree Pollen Mix ... Western 3 Tree Pollen Mix …

Lactitol

Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from lactose. It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet as table sugar (i.e. sucrose). Clinically, lactitol has been investigated for use as an osmotic laxative and, along with other non-absorbable disaccharides...
Approved
Investigational
Matched Iupac: … (2S,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexane-1,2,3,5,6-pentol …
Matched Description: … [A190915,A190918] Pizensy, an oral lactitol powder for solution, was approved by the FDA for use in ... [A190918] It is used in food manufacturing as a nutritive sweetener and is approximately 35% as sweet ... Lactitol, also known as 4-β-D-galactopyranosyl-D-glucitol, is a sugar alcohol synthesized from [lactose …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Drugs for Constipation …

Ipecac

Ipecac is obtained from the plant Cephaelis ipecacuanha and contains a number of emetic alkaloids including emetine and cephaeline. Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. The FDA does not have currently any approved product containing ipecac, however, ipecac as an...
Approved
Withdrawn
Matched Description: … packages of 1 fluid ounce (30 ml) for the emergency use to cause vomiting in poisoning. ... [L2753] Ipecac was approved by Health Canada as an OTC but all those products are now discontinued. ... Ipecac is obtained from the plant _Cephaelis ipecacuanha_ and contains a number of emetic alkaloids including …

Migalastat

Fabry disease is a rare, progressive genetic disorder characterized by a defective GLA gene that causes a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients with Fabry disease, builds up in the blood vessels, the kidneys,...
Approved
Investigational
Matched Iupac: … (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol …
Matched Description: … a deficiency in the enzyme alpha-Galactosidase A (alpha-Gal A). ... for the treatment of Fabry disease in adults who have amenable GLA variants. ... This enzyme is responsible for breaking down glycosphingolipid substrate that, when deficient in patients …
Matched Categories: … Alpha-Galactosidase A (alpha-Gal A) Pharmacological Chaperones …

Poa annua pollen

Poa annua pollen is the pollen of the Poa annua plant. Poa annua pollen is mainly used in allergenic testing.
Approved
Matched Description: … Poa annua pollen is mainly used in allergenic testing. …

Belladonna

Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in the nightshade family Solanaceae. Its roots, leaves and fruits contain DB00424, DB00747, and mostly, DB00572. These alkaloids are naturally-occurring muscarinic antagonists. DB00572 is a non-selective muscarinic antagonist that is mainly used as an adjunct for...
Approved
Experimental
Matched Description: … Belladonna is a poisonous plant and belladonna intoxication from accidental ingestion may result in a ... Belladonna, also known as atropa belladonna or deadly nightshade, is a perennial herbaceous plant in ... [DB00572] is a non-selective muscarinic antagonist that is mainly used as an adjunct for anaesthesia. …

Tilia americana pollen

Tilia americana pollen is the pollen of the Tilia americana plant. Tilia americana pollen is mainly used in allergenic testing.
Approved
Matched Description: … Tilia americana pollen is mainly used in allergenic testing. …

Atractylodes japonica root

Approved

Vemurafenib

Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E. It exerts its function by binding to the ATP-binding domain of the mutant BRAF. Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann...
Approved
Matched Iupac: … N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide …
Matched Description: … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012] ... Vemurafenib is a competitive kinase inhibitor with activity against BRAF kinase with mutations like V600E …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Recombinant stabilized RSV B prefusion F antigen

Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Synonyms: … RSV subgroup B stabilized prefusion F protein …
Matched Name: … Recombinant stabilized RSV B prefusion F antigen …
Matched Description: … Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... The vaccine comprises two antigens - the other being [recombinant stabilized RSV A prefusion F antigen ... received subsequent approval in August 2023 for use in pregnant individuals for the protection of infants …

Deferasirox

Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Approved
Investigational
Matched Iupac: … 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid …
Matched Description: … in patients receiving long term blood transfusions. ... Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Febind-F 90 mg Film Kaplı Tablet, 30 ADET ... Febind-F 180 mg Film Kaplı Tablet, 30 ADET ... Febind-F 360 mg Film Kaplı Tablet, 30 ADET …

Sunitinib

Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. On January 26, 2006, the agent was formally approved by the US FDA for the indications of treating renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST). For these purposes, sunitinib is generally available as an orally administered formulation....
Approved
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl ... -1H-pyrrole-3-carboxamide …
Matched Description: … Sunitinib is a small-molecule multi-targeted receptor tyrosine kinase (RTK) inhibitor. ... In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3. ... These include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth factor …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A7 Substrates with a Narrow Therapeutic Index …

Capra hircus skin

Capra hircus skin or pelt is used in allergenic testing.
Approved
Matched Description: … Capra hircus skin or pelt is used in allergenic testing. …

Bilastine

Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Approved
Investigational
Matched Iupac: … 2-[4-(2-{4-[1-(2-ethoxyethyl)-1H-1,3-benzodiazol-2-yl]piperidin-1-yl}ethyl)phenyl]-2-methylpropanoic …
Matched Description: … Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor ... , has a rapid onset and prolonged duration of action. …
Matched Categories: … Antihistamines for Systemic Use ... Heterocyclic Compounds, 2-Ring …

Avalglucosidase alfa

Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Description: … [A232955] Avalglucosidase alfa is a recombinant form of GAA that restores deficient enzyme levels. ... Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe ... GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. …

Ramelteon

Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Iupac: … N-{2-[(8S)-1H,2H,6H,7H,8H-indeno[5,4-b]furan-8-yl]ethyl}propanamide …
Matched Description: … Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors ... in the suprachiasmatic nucleus (SCN). ... It is used for insomnia, particularly delayed sleep onset. …

Certoparin

Certoparin is part of the heparins of low molecular weight that presents high activity against the coagulation factor Xa. It is normally used to prevent deep venous thrombosis.
Approved
Investigational

Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen

Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a sterile vaccine that contains saccharides of the capsular antigens of Streptococcus pneumoniae serotype 4 individually conjugated to the CRM197 protein, a nontoxic variant of diphtheria toxin isolated from cultures of Corynebacterium diphtheriae strain C7 (β197). It is...
Approved
Investigational
Matched Description: … It is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes ... 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection. ... Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen is a …
Displaying drugs 951 - 975 of 15549 in total