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Displaying drugs 1251 - 1275 of 15697 in total
Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid …
Matched Description: … Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary ... It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache ... Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … Antiphlogistine Rub A-535 No Odour Fmla Ont …
Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It was withdrawn from the United States market in April 1994.
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's ... It was withdrawn from the United States market in April 1994. …
Matched Categories: … Corticosteroids for Systemic Use …
Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be effective...
Approved
Matched Iupac: … (1R,2R,4S,5S,7S)-7-{[(2S)-3-hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{ …
Matched Description: … Methscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh ... The oral tablets are used as an adjunct therapy for the treatment of peptic ulcer and is shown to be ... Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products …
Matched Salts cas: … 6106-46-3
Matched Categories: … Drugs for Functional Gastrointestinal Disorders …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H1N1) …
Matched Name: … Influenza A virus subtype H1N1 haemagglutinin, recombinant …
Varenicline is a prescription medication used to treat smoking addiction. This medication is the first approved nicotinic receptor partial agonist. Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor. In addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full...
Approved
Investigational
Matched Iupac: … 5,8,14-triazatetracyclo[10.3.1.0^{2,11}.0^{4,9}]hexadeca-2(11),3,5,7,9-pentaene …
Matched Description: … Varenicline is a prescription medication used to treat smoking addiction. ... A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. ... Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Drugs Used in Addictive Disorders ... Drugs Used in Nicotine Dependence …
Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant...
Approved
Investigational
Matched Iupac: … 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2- …
Matched Description: … tyrosine kinase inhibitor used as a first-line treatment for CML. ... A Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic ... for chronic myelogenous leukemia (CML). …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Safinamide is for the treatment of parkinson's disease. It was approved in Europe in February 2015, and in the United States on March 21, 2017.
Approved
Investigational
Matched Iupac: … (2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl)amino]propanamide …
Matched Description: … Safinamide is for the treatment of parkinson's disease. ... It was approved in Europe in February 2015, and in the United States on March 21, 2017. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Description: … DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization ... A phase 1 study in 5 patients concluded that DCA was safe, but wasn't designed to establish effectiveness ... and removal of a wide variety of skin and tissue lesions), but was cancelled post market. …
Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Iupac: … 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2
Matched Description: … In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant ... In a randomized trial, the median metastasis-free survival for patients taking apalutamide was 40.5 months ... compared to 16.2 months for patients taking a placebo [L1295]. …
Matched Categories: … MATE 2 Inhibitors …
Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.
Approved
Matched Iupac: … 2-({bis[(carboxymethyl)sulfanyl]methyl}sulfanyl)acetic acid …
Matched Description: … It is indicated for use in viral rhinitis/ the common cold. ... Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. …
Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood.
Approved
Investigational
Matched Description: … Treosulfan is under investigation in Allogeneic Haematopoietic Stem Cell Transplantation. ... Treosulfan has been investigated for the treatment of Lymphoblastic Leukemia, Acute, Childhood. …
Corn allergenic extract is used in allergenic testing.
Approved
Matched Description: … Corn allergenic extract is used in allergenic testing. …
Strontium chloride (SrCl2) is a salt of strontium and chloride. SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin containing nerve endings that have become exposed by gum recession [A33167, A33168]. This kind of barrier protection for tooth hypersensitivity has, however, been...
Approved
Matched Iupac: … strontium(2+) dichloride …
Matched Description: … SrCl2 is useful in reducing tooth sensitivity by forming a barrier over microscopic tubules in the dentin ... Such strontium chloride toothpaste formulations may subsequently not be available for sale anymore in ... Strontium chloride (SrCl2) is a salt of strontium and chloride. …
Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Description: … It is used as a solvent and base material in organic synthesis reactions. ... Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted …
Matched Salts cas: … 8006-64-2
Matched Categories: … Compounds used in a research, industrial, or household setting …
Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease.
Approved
Investigational
Matched Description: … Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. ... Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A polysaccharide with glucose units linked as in CELLOBIOSE. It is the chief constituent of plant fibers, cotton being the purest natural form of the substance. As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.
Approved
Experimental
Investigational
Matched Description: … As a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials ... A polysaccharide with glucose units linked as in CELLOBIOSE. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic acid. Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by the FDA....
Approved
Matched Description: … It is used as a thickening agent and stabilizer in emulsions. ... Xanthan gum is a direct food additive permitted for direct addition to food for human consumption by ... Xanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation …
Matched Categories: … Compounds used in a research, industrial, or household setting …
A potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Approved
Investigational
Matched Iupac: … (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H,6H,7H,8H-imidazo[4,5-d][1,3]diazepin-8- …
Matched Description: … A potent inhibitor of adenosine deaminase. ... The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell …
Matched Categories: … Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index …
Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). AMD is the leading cause of vision loss in developed countries for people over 50 years old, with...
Approved
Investigational
Matched Description: … This approval is based on the positive results obtained from 2 phase 3 clinical trials GATHER1 and GATHER2 ... [L47696] AMD is the leading cause of vision loss in developed countries for people over 50 years old, ... for GA. …
Matched Salts cas: … 1491144-00-3
Sodium iodide is a water-soluble ionic compound with a crystal lattice. Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition but is more commonly used in veterinary medicine. Radiolabelled compound, DB09293, is used as a diagnostic tool to evaluate thyroid function...
Approved
Matched Description: … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition ... [L2065] but is more commonly used in veterinary medicine. ... Sodium iodide is a water-soluble ionic compound with a crystal lattice. …
Matched Mixtures name: … GNP Idoinde Tincture 2% Mild ... LEADER 2% Mild Iodine Tincture …
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Iodide has been investigated for the treatment of Goiter, Nodular.
Approved
Experimental
Matched Description: … Iodide has been investigated for the treatment of Goiter, Nodular. …
Biguanide has been investigated for the treatment of Diabetes Mellitus.
Approved
Investigational
Matched Description: … Biguanide has been investigated for the treatment of Diabetes Mellitus. …
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,5S,9aS,9bR,10S,11aS)-1-[2-(acetyloxy)acetyl]-5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is indicated for treatment of endogenous anterior uveiti. ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. …
Displaying drugs 1251 - 1275 of 15697 in total