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Displaying drugs 4876 - 4900 of 5853 in total
Propafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
Investigational
Matched Synonyms: … 1-propanone, 1-(2-((2r)-2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl- …
Investigational
Matched Synonyms: … 2-[4-(1-Methyl-4-pyridin-4-yl-lH-pyrazol-3-yl)-phenoxymethyl]-quinoline succinic acid …
Matched Iupac: … 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Investigational
Cibinetide has been used in trials studying the basic science of Depression.
Investigational
Matched Iupac: … carbamoyl}-3-carboxypropyl]carbamoyl}-3-methylbutyl]carbamoyl}-3-carbamoylpropyl]carbamoyl}-4-{[(2S)-5- ... [(1S)-1-{[(1S)-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}ethyl]carbamoyl}-3-methylbutyl ... oxopyrrolidin-2-yl]formamido}butanoic acid ... (4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(1S)-1-{[(1S)-2-carbamoyl-1-{ …
A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Experimental
Investigational
Matched Iupac: … (1S,3aS,3bS,9aR,9bS,10S,11aR)-10-hydroxy-1-(2-hydroxyacetyl)-9a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H …
Investigational
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Description: … recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid …
Fenoverine has been used in trials studying the treatment of Irritable Bowel Syndrome.
Investigational
Matched Iupac: … 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-1-(10H-phenothiazin-10-yl)ethan-1-one …
Investigational
Matched Synonyms: … 1-(((z)-hexadec-1-en-1-yl)oxy)-3-((2-oxido-1,3,2-oxazaphospholidin-2-yl)oxy)propan-2-yl (4z,7z,10z,13z ... 4,7,10,13,16,19-docosahexaenoic acid, 2-((1z)-1-hexadecen-1-yloxy)-1-(((2-oxido-1,3,2-oxazaphospholidin ... -2-yl)oxy)methyl)ethyl ester, (4z,7z,10z,13z,16z,19z)- …
Matched Iupac: … 1-[(1Z)-hexadec-1-en-1-yloxy]-3-[(2-oxo-1,3,2lambda5-oxazaphospholidin-2-yl)oxy]propan-2-yl (4Z,7Z,10Z …
Investigational
Matched Name: … 2-O, 3-O desulfated heparin …
Investigational
Matched Iupac: … N-{4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl}-1,3-diazinan-2-imine …
Encenicline has been investigated for the treatment of Cognition, Schizophrenia, Alzheimer's Disease, Cardiac Repolarization, and Central Nervous System Diseases.
Investigational
Matched Iupac: … N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide …
Evatanepag has been used in trials studying the treatment of Tibial Fractures.
Investigational
Matched Iupac: … 2-[3-({N-[(4-tert-butylphenyl)methyl]pyridine-3-sulfonamido}methyl)phenoxy]acetic acid …
Enobosarm has been used in trials studying the treatment of Stress Urinary Incontinence and Triple Negative Breast Cancer.
Investigational
Matched Iupac: … (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide …
Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
Investigational
Matched Iupac: … (2R)-N-(4-chlorophenyl)-2-[(1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
BFH772 is under investigation in clinical trial NCT01449591 (Safety, Tolerability and Efficacy of BFH772 in Rosacea Patients).
Investigational
Matched Iupac: … 6-{[6-(hydroxymethyl)pyrimidin-4-yl]oxy}-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide …
Lorukafusp alfa is under investigation in clinical trial NCT01334515 (Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma).
Investigational
Pepinemab is under investigation in clinical trial NCT03769155 (VX15/2503 With or Without Ipilimumab and/or Nivolumab in Patients With Resectable Stage IIIB-D Melanoma).
Investigational
Investigational
Matched Iupac: … -({[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxy}methyl)-5,9,13-trimethyl-2,10-dioxo ... 2-[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-{[(2R,3R,4R,5S,6R)-4-(dimethylamino)-5-{[(2S,4R,5S,6S)-5-[(4-fluorophenyl ... )methoxy]-4-hydroxy-4,6-dimethyloxan-2-yl]oxy}-3-hydroxy-6-methyloxan-2-yl]oxy}-16-ethyl-4-hydroxy-15 …
Uric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this...
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype 5 carrying the gene for the human frataxin protein …
Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Investigational
Matched Synonyms: … (S)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone ... 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Iupac: … 4-hydroxy-3-[(1S)-3-oxo-1-phenylbutyl]-2H-chromen-2-one …
Matched Description: … S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] …
Investigational
Matched Synonyms: … 4h-3,1-benzoxazin-4-one, 6-ethoxy-7-methoxy-2-(2-(methylthio)phenyl)- ... 6-ethoxy-7-methoxy-2-(2-methylsulfanylphenyl)-3,1-bensoxazin-4-one …
Matched Iupac: … 6-ethoxy-7-methoxy-2-[2-(methylsulfanyl)phenyl]-4H-3,1-benzoxazin-4-one …
PF-00446687 has been investigated for the treatment of Erectile Dysfunction.
Investigational
Displaying drugs 4876 - 4900 of 5853 in total