Displaying drugs 476 - 500 of 771 in total
Pyridoxine phosphate
Experimental
Matched Synonyms: … Pyridoxine 5-phosphate …
Matched Name: … Pyridoxine phosphate …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … Pyridoxine phosphate …
Matched Categories: … Enzymes and Coenzymes …
Etanercept
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … [L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region ... variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ENBREL (PRE-FILLED SYRINGE) ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Eucept 50 mg / mL Solution for Injection in Pre-filled Syringe …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ENBREL (PRE-FILLED SYRINGE) ... Enbrel Solution for Injection in a Pre-filled Pen 50mg ... Eucept 50 mg / mL Solution for Injection in Pre-filled Syringe …
Aluminium phosphate
Approved
Investigational
Matched Synonyms: … Aluminum phosphate …
Matched Name: … Aluminium phosphate …
Matched Iupac: … aluminium(3+) phosphate …
Matched Categories: … Alimentary Tract and Metabolism ... aluminium phosphate ... Aluminum and magnesium containing antacids ... Phosphoric Acids ... Phosphorus Acids …
Matched Name: … Aluminium phosphate …
Matched Iupac: … aluminium(3+) phosphate …
Matched Categories: … Alimentary Tract and Metabolism ... aluminium phosphate ... Aluminum and magnesium containing antacids ... Phosphoric Acids ... Phosphorus Acids …
Phosphate ion
Experimental
Matched Synonyms: … Phosphate …
Matched Name: … Phosphate ion …
Matched Iupac: … phosphate …
Matched Categories: … Phosphate salts ... Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …
Matched Name: … Phosphate ion …
Matched Iupac: … phosphate …
Matched Categories: … Phosphate salts ... Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …
Dihydroxyacetone phosphate
Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse.
Investigational
Matched Synonyms: … Glycerone phosphate ... 3-hydroxy-2-oxopropyl phosphate ... 1,3-Dihydroxyacetone 1-phosphate …
Matched Name: … Dihydroxyacetone phosphate …
Matched Description: … Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. ... Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse. …
Matched Categories: … Sugar Phosphates …
Matched Name: … Dihydroxyacetone phosphate …
Matched Description: … Dihydroxyacetone phosphate is an important intermediate in lipid biosynthesis and in glycolysis. ... Dihydroxyacetone phosphate has been investigated for the treatment of Lymphoma, Large-Cell, Diffuse. …
Matched Categories: … Sugar Phosphates …
Isoflurophate
An irreversible cholinesterase inhibitor with actions similar to those of echothiophate. It is a powerful miotic used mainly in the treatment of glaucoma. Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically. (From Martindale, The Extra Pharmacopoeia, 29th ed, p1330)
Approved
Investigational
Withdrawn
Matched Synonyms: … Fluorodiisopropyl phosphate ... O,O'-diisopropyl phosphoryl fluoride …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Matched Description: … Its vapor is highly toxic and it is recommended that only solutions in arachis oil be used therapeutically …
Swertia japonica whole flowering
Swertia japonica whole flowering is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Swertia japonica whole flowering …
Matched Description: … Swertia japonica whole flowering is a plant/plant extract used in some OTC (over-the-counter) products …
Matched Description: … Swertia japonica whole flowering is a plant/plant extract used in some OTC (over-the-counter) products …
NADPH
Experimental
Matched Synonyms: … Dihydronicotinamide-adenine dinucleotide phosphate ... Reduced nicotinamide adenine dinucleotide phosphate …
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... [({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … )oxy](hydroxy)phosphoryl}oxy)methyl]-4-hydroxyoxolan-3-yl]oxy}phosphonic acid ... [({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Categories: … Enzymes and Coenzymes ... Nucleic Acids, Nucleotides, and Nucleosides …
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Description: … In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing ... IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and ... that are expressed on the tumour cells in certain cancers; however, the antigen is not tumour-specific and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML ... Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe ... KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 20MG/0.4ML …
Guselkumab
Guselkumab is a human immunoglobulin G1 lambda (IgG1λ) monoclonal antibody that selectively blocks interleukin-23. IL-23 is an inflammatory cytokine that activates the CD4+ T-helper (Th17) cell pathway to mediate the inflammatory cascade that induces psoriatic plaque formation . In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in...
Approved
Investigational
Matched Description: … In clinical trials, guselkumab demonstrated improved skin clearance and symptomatic improvements in dermatological …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Tremfya One-press ... Tremfya One-Press 100mg/ml Solution for Injection ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Tremfya One-press ... Tremfya One-Press 100mg/ml Solution for Injection ... TREMFYA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML …
Insulin glulisine
Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and proteolysis among many other functions. ... tissues such as the liver, fat cells, and skeletal muscle. ... glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN ... Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen …
Dexfosfoserine
The phosphoric acid ester of serine.
Experimental
Matched Synonyms: … Serine phosphate …
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … The phosphoric acid ester of serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Aracytidine 5'-monophosphate
Experimental
Matched Synonyms: … Aracytidine 5'-phosphate ... Cytosine arabinose-5'-phosphate ... 1-beta-D-Arabinofuranosylcytosine 5'-phosphate …
Muparfostat
Muparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic activity.
Investigational
Matched Synonyms: … Mannopentaose phosphate sulfate ... Sulfated mannopentaose phosphate ... -D-MANNAN, (1->3)-, 6-(DIHYDROGEN PHOSPHATE) TRIS(HYDROGEN SULFATE) …
Menadiol diphosphate
Approved
Nutraceutical
Matched Synonyms: … Menadiol phosphate ... Menadiol bis(dihydrogen phosphate) …
Benzylpenicilloyl polylysine
Benzylpenicilloyl polylysine is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.
Approved
Matched Products: … Pre-pen …
Ribose-5-phosphate
Experimental
Matched Synonyms: … D-Ribose 5-phosphate ... aldehydo-D-ribose 5-phosphate …
Matched Name: … Ribose-5-phosphate …
Matched Categories: … Sugar Phosphates …
Matched Name: … Ribose-5-phosphate …
Matched Categories: … Sugar Phosphates …
2'-cytidylic acid
Experimental
Matched Synonyms: … Cytidine 2'-phosphate ... Cytidine, 2'-phosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Mepolizumab
Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically defined as absolute eosinophil levels of 1500/mm3 or more) is associated with a spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and hypereosinophilic syndrome (HES). The pathogenesis of eosinophilia is complex, but IL-5 is recognized as...
Approved
Investigational
Matched Description: … Activated eosinophils further stimulate an inflammatory response and also induce tissue lesions and promote ... Eosinophils are involved in inflammatory immune responses, and prolonged hypereosinophilia (typically ... spectrum of diseases, including severe asthma, eosinophilic granulomatosis with polyangiitis (EGPA), and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/ML …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … NUCALA SOLUTION FOR INJECTION IN PRE-FILLED PEN 100MG/ML ... NUCALA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 100MG/ML …
Dulaglutide
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and ... [A236070] Dulaglutide was initially approved by the FDA in 2014, and in February 2020 was approved for ... use in patients with T2DM and multiple cardiovascular risk factors for the prevention of cardiovascular …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Trulicity 1.5mg solution for injection in pre-filled pen ... Trulicity 0.75mg solution for injection in pre-filled pen …
Glucagon
Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643]
Glucagon was granted FDA...
Approved
Matched Description: … diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and ... Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Gvoke PFS 1 mg Pre-filled Syringe ... Gvoke PFS 0.5 mg Pre-filled Syringe …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Gvoke PFS 1 mg Pre-filled Syringe ... Gvoke PFS 0.5 mg Pre-filled Syringe …
Golimumab
Golimumab is a human IgG1қ monoclonal antibody derived from immunizing genetically engineered mice with human TNFα. Golimumab binds and inhibits soluble and transmembrane human TNFα. Increased TNFα is associated with chronic inflammation. Thus golimumab is indicated for use in adults (i) as an adjunct to methotrexate treatment in patients with...
Approved
Matched Description: … Golimumab binds and inhibits soluble and transmembrane human TNFα. ... Additionally in children and adolescents taking golimumab, there have been lymphoma and other malignancies ... In the U.S. and Canada, golimumab is marketed under the brand name Simponi®. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Solution for Injection in Pre-filled Syringe 100 mg/1.0 ml ... Simponi Solution for Injection in Pre-filled Syringe 50 mg/0.5 ml ... SIMPONI SOLUTION FOR INJECTION IN PRE-FILLED PEN 45MG/0.45ML …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Solution for Injection in Pre-filled Syringe 100 mg/1.0 ml ... Simponi Solution for Injection in Pre-filled Syringe 50 mg/0.5 ml ... SIMPONI SOLUTION FOR INJECTION IN PRE-FILLED PEN 45MG/0.45ML …
Bazlitoran
Bazlitoran is under investigation in clinical trial NCT02092909 (Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia).
Investigational
Matched Synonyms: … Antagonist of the endosomal Toll-like receptors (TLRs) 7, 8, and 9 …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Displaying drugs 476 - 500 of 771 in total