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Displaying drugs 51 - 75 of 85 in total

Ancrod

Ancrod, marketed as Viprinex, is a defibrinogenating agent derived from Malayan pit viper venom. The defribrinogenation of blood results in an anticoagulant effect. Currently, Viprinex®/ancrod is not approved or marketed in any country, but is being investigated as a stroke treatment in worldwide clinical trials. In January 2005, the U.S....
Approved
Investigational

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Description: … [L5783] Due to the possibility of fatal overdose and liver failure associated with the incorrect use …
Matched Mixtures name: … JEGAMSAN Extract ... Dometuss-G ... G-Dologen …
Matched Products: … PANADOL TABLET 1 g ... PARTEMOL 1 G/100 ML INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... PARACETAMOL 1 G SOLUCIÓN PARA INFUSIÓN INTRAVENOSA …

Betrixaban

Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Description: … VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Andexanet alfa

Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018. It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with rivaroxaban and apixaban...
Approved
Investigational
Matched Description: … inhibitors that promote anticoagulation in situations where blood clotting is unfavourable, such as in deep vein …

Cephalexin

Cephalexin is the first of the first generation cephalosporins.[A179071,A179074] This antibiotic contains a beta lactam and a dihydrothiazide. Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.[A179083,Label] Cephalexin was approved by the FDA on 4 January 1971.
Approved
Investigational
Vet approved
Matched Synonyms: … (6R,7R)-7-{[(2R)-2-amino-2-phenylacetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic ... 7-beta-(D-alpha-Amino-alpha-phenylacetylamino)-3-methyl-3-cephem-4-carboxylic acid ... 7-(D-alpha-Aminophenylacetamido)desacetoxycephalosporanic acid …
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …
Matched Products: … KEFLEX 1 G TABLETAS ... BILFASIN 1 G FILM KAPLI TABLET,10 TABLET ... BILFASIN 1 G FILM KAPLI TABLET ,16 TABLET …

Sorbitol

A polyhydric alcohol with about half the sweetness of sucrose. Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures.
Approved
Matched Synonyms: … G-ol …
Matched Mixtures name: … Char-flo With Sorbitol - Sus ... MICROLAX LAVMAN, 10 G ... MICROLAX LAVMAN, 30 G …

Dalteparin

Dalteparin, a low molecular weight heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa origin, is an anticoagulant. It is composed of strongly acidic sulphated polysaccharide chains with an average molecular weight of 5000 and about 90% of the material within the range of 2000-9000....
Approved
Matched Synonyms: … alpha-heparin …
Matched Description: … heparin (LMWH) prepared by nitrous acid degradation of unfractionated heparin of porcine intestinal mucosa ... LMWHs have a more predictable response, a greater bioavailability, and a longer anti-Xa half life than …
Matched Products: … Fragmin 10.000 IE/1 ml - Ampullen ... -liq 2500 Iu(anti-XA)/ml ... FRAGMIN 2500 U.I/ML (ANTI-XA) VIAL DE 4 ML …

Acenocoumarol

Acenocoumarol is a coumarin derivative used as an anticoagulant. Coumarin derivatives inhibit the reduction of vitamin K by vitamin K reductase. This prevents carboxylation of vitamin K-dependent clotting factors, II, VII, IX and X, and interferes with coagulation. Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. Patients...
Approved
Investigational
Matched Synonyms: … 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one ... 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one ... 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin …
Matched Iupac: … 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one …
Matched Description: … [A188739] Hematocrit, hemoglobin, international normalized ratio and liver panel should be monitored. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Sucralfate

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Categories: … Anti-Ulcer Agents …
Matched Products: … Sulcrate Sus 100mg/ml ... SUCRALFATO 1 G TABLETAS ... APO-SUCRALFATE TABLET 1 g …

Lidocaine

Ever since its discovery and availability for sale and use in the late 1940s, lidocaine has become an exceptionally commonly used medication . In particular, lidocaine's principal mode of action in acting as a local anesthetic that numbs the sensations of tissues means the agent is indicated for facilitating local...
Approved
Vet approved
Matched International brands: … Lidoject-1 …
Matched Synonyms: … alpha-diethylamino-2,6-dimethylacetanilide …
Matched Description: … As a result, lidocaine is also considered a class Ib anti-arrhythmic agent [L5930, L5948, F4468]. …
Matched Mixtures name: … Lidotral 5 Percent and Hydrocortisone 1 Percent with Peptides and Arnica ... Small Cuts and Burns ... Central Vein Catheterization Kit …
Matched Products: … Meijer Lidocaine Pain Relief Patch Assortment Small ... Burn Jel 20 mg/g ... TLC Plus Anesthetic G …

Sodium tetradecyl sulfate

An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched International brands: … Fibro-Vein …
Matched Products: … Tromboject 1% ... Trombovar Inj 1% …

Ximelagatran

Ximelagatran is an anticoagulant intended to become a replacement for warfarin by overcoming the dietary restrictions, drug interaction, and monitoring issues associated with the former. In 2006, its manufacturer AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver damage) during trials, and to discontinue...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-yl]- 2-oxo-ethyl]amino]acetate ... ethyl 2-[[(1R)-1-cyclohexyl-2- [(2S)-2-[[4-(N'-hydroxycarbamimidoyl) phenyl]methylcarbamoyl]azetidin- …
Matched Iupac: … -1-yl]-2-oxoethyl]amino}acetate ... ethyl 2-{[(1R)-1-cyclohexyl-2-[(2S)-2-[({4-[(Z)-N'-hydroxycarbamimidoyl]phenyl}methyl)carbamoyl]azetidin …
Matched Description: … AstraZeneca announced that it would not attempt to market ximelagatran after reports of hepatotoxicity (liver …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Mycophenolate mofetil

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal, and cardiac transplants. It is...
Approved
Investigational
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Desirudin

Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Description: … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients …

Nadroparin

Nadroparin is a low molecular weight heparin (LMWH) which, when bound to antithrombin III (ATIII), accelerates the inactivation of factor II and factor Xa. Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa. The amplification of the fibrin clotting cascade is stopped once...
Approved
Investigational
Matched Products: … FRAXIPARINE 1 ML ... FRAXIPARINE TX 1 ML ... FRAXODI 19000 IU AXA/1 ML SC ENJEKTABL SOLUSYON 2 ENJEKTOR …

Ranibizumab

Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … The development of ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was …
Matched Products: … 1 Ranivisio ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... LUCENTİS 10 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET …

Ardeparin

Ardeparin, marketed under the US trade name Normiflo, is a low molecular weight heparin (LMWH) anticoagulant used for the prevention of postoperative venous thrombosis. Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. Its molecular weight ranges from 2000 to 15,000 with an average molecular weight...
Approved
Investigational
Withdrawn
Matched Description: … Ardeparin is derived via peroxide degradation of heparin extracted from porcine intestinal mucosa. …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Mixtures name: … EUSAPRIM K SUS F KDR ... CO-TRIPIRIM 5 ML 1 AMPUL ... Nu-cotrimox Sus 40/8mg/ml …
Matched Categories: … Anti-Infective Agents ... Anti-Infective Agents, Urinary ... MATE 1 Inhibitors ... MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring …

Parnaparin

Parnaparin is an heparin of low molecular weight with antithrombotic effects.
Approved
Investigational

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Iupac: … {7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo[15.2.1.1^{2,5}.1^ ... carbamoylethyl)-3,14,19-tris(carbamoylmethyl)-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1- …
Matched Mixtures name: … Cavan Alpha ... B Complex W Vit C W Non-med Yeast&liver Tab ... PNV Tabs 29-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … VITAMINA B12 1 MG/ML INYECTABLE ... CIANOCOBALAMINA - VITAMINA B-12 X 1 ML ... VITAMINA B12 SOLUCION INYECTABLE 1 MG/ML …

Apixaban

Apixaban is an oral, direct, and highly selective factor Xa (FXa) inhibitor of both free and bound FXa, as well as prothrombinase, independent of antithrombin III for the prevention and treatment of thromboembolic diseases[Label,A6897]. It is marketed under the name Eliquis[Label,L6043]. Apixaban was approved by the FDA on December 28,...
Approved
Matched Iupac: … 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Mixtures name: … TRIFEN 100 ML SUS. ... G Tussin AC ... LUDICODINE SURUP, 180 G …

Peginterferon alfa-2b

Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver ... is derived from the alfa-2b moeity of recombinant human interferon and acts by binding to human type 1 …
Matched Categories: … Anti-Infective Agents ... Interferon alpha ... Interferon-alpha …

Angiotensin II

Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational

Rivaroxaban

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … FDA approved on July 1, 2011. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 51 - 75 of 85 in total