Displaying drugs 826 - 850 of 1167 in total
Emavusertib
Investigational
Matched Synonyms: … 4-oxazolecarboxamide, n-(5-((3r)-3-hydroxy-1-pyrrolidinyl)-2-(4-morpholinyl)oxazolo(4,5-b)pyridin-6-yl …
Matched Iupac: … N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin …
Matched Iupac: … N-{5-[(3R)-3-hydroxypyrrolidin-1-yl]-2-(morpholin-4-yl)-[1,3]oxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin …
Riociguat
Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Synonyms: … Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminate …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. …
Matched Iupac: … methyl N-(4,6-diamino-2-{1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}pyrimidin-5-yl)-N-methylcarbamate …
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. …
Gimatecan
Gimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Investigational
Matched Synonyms: … (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline ... (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline ... 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy …
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Description: … Neisseria meningitidis group c capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
4-Iodobenzo[B]Thiophene-2-Carboxamidine
Experimental
Matched Name: … 4-Iodobenzo[B]Thiophene-2-Carboxamidine …
Ziprasidone
Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … [A190525] These mental illnesses can often be accompanied by comorbidities such as depression and substance ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to ... [ziprasidone] among others, and are generally thought to be as efficacious as first generation antipsychotics …
Matched Products: … Truemed Group LLC …
Matched Products: … Truemed Group LLC …
D-glucose
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Description: … [A19399] It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic ... through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and …
Matched Mixtures name: … Ionosol B and Dextrose ... SODIUM CHLORIDE 0.2% AND GLUCOSE 5% INTRAVENOUS INFUSION BP ... SODIUM CHLORIDE 0.9% AND GLUCOSE 5% INTRAVENOUS INFUSION BP …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … B. BRAUN 50% GLUCOSE INJECTION BP ... B. BRAUN 5% GLUCOSE IV INFUSION BP ... B. BRAUN 20% GLUCOSE IV INFUSION BP …
Matched Mixtures name: … Ionosol B and Dextrose ... SODIUM CHLORIDE 0.2% AND GLUCOSE 5% INTRAVENOUS INFUSION BP ... SODIUM CHLORIDE 0.9% AND GLUCOSE 5% INTRAVENOUS INFUSION BP …
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … B. BRAUN 50% GLUCOSE INJECTION BP ... B. BRAUN 5% GLUCOSE IV INFUSION BP ... B. BRAUN 20% GLUCOSE IV INFUSION BP …
Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism …
Hydroxypropyl betadex
Hydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
Investigational
Matched Synonyms: … 2-Hydroxypropyl-b-cyclodextrin …
Matched Description: … NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type …
Matched Description: … NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type …
Alteplase
Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an …
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Trenbolone
Trenbolone, also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and appetite. To increase its effective half-life, trenbolone is administered as a prodrug as an ester conjugate such as trenbolone acetate, trenbolone enanthate, or trenbolone cyclohexylmethylcarbonate. Plasma lipases then cleave the ester group...
Vet approved
Matched Synonyms: … 17-b-Hydroxyestra-4,9,11-trien-3-one …
Matched Description: … , also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and ... Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … , also known as trienolone or trienbolone, is a steroid used on livestock to increase muscle growth and ... Plasma lipases then cleave the ester group in the bloodstream leaving free trenbolone. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Raloxifene
Raloxifene is a second generation selective estrogen receptor modulator (SERM) that mediates anti-estrogenic effects on breast and uterine tissues, and estrogenic effects on bone, lipid metabolism, and blood coagulation.[A4979,T28] Exhibiting tissue-specific effects distinct from estradiol, raloxifene is the first of the benzothiophene group of antiestrogens to be labelled a SERM....
Approved
Investigational
Matched Synonyms: … (2-(4-Hydroxyphenyl)-6-hydroxybenzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)methanone …
Matched Description: … However, due to the off-target actions by HRT, newer non-hormonal agents such as raloxifene and [tamoxifen ... of antiestrogens to be labelled a SERM. ... Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … However, due to the off-target actions by HRT, newer non-hormonal agents such as raloxifene and [tamoxifen ... of antiestrogens to be labelled a SERM. ... Exhibiting tissue-specific effects distinct from [estradiol], raloxifene is the first of the benzothiophene group …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Thieno[2,3-B]Pyridine-2-Carboxamidine
Experimental
Matched Name: … Thieno[2,3-B]Pyridine-2-Carboxamidine …
Matched Iupac: … [amino({thieno[2,3-b]pyridin-2-yl})methylidene]azanium …
Matched Iupac: … [amino({thieno[2,3-b]pyridin-2-yl})methylidene]azanium …
Granisetron
A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Approved
Investigational
Matched Description: … A serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … GRANISETRON B. BRAUN ... GRANISETRON B BRAUN 2MG …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … GRANISETRON B. BRAUN ... GRANISETRON B BRAUN 2MG …
Ajmaline
An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Synonyms: … ,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b] …
Matched Description: … It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac ... Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a ... countries for the treatment of atrial fibrillation in patients with the Wolff–Parkinson–White syndrome and …
Matched Categories: … Ajmaline and derivatives …
Matched Description: … It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac ... Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a ... countries for the treatment of atrial fibrillation in patients with the Wolff–Parkinson–White syndrome and …
Matched Categories: … Ajmaline and derivatives …
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4- …
Matched Iupac: … 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … T & B ... Bio-moxifloxacin …
Matched Iupac: … 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … T & B ... Bio-moxifloxacin …
Alectinib
Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Hydrocortisone butyrate
Approved
Vet approved
Matched Synonyms: … H-17-B …
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Corticosteroids, Moderately Potent (Group II) …
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Corticosteroids, Moderately Potent (Group II) …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Description: … Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation ... PGs contribute to inflammation and pain signalling. ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). …
Matched Mixtures name: … DICLOVITH-B ... DICLOVITH-B-FRT ... Diclo-B G.L. - Kapseln …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... DICLOFENAC TEVA BV ... DICLOFENAC SODICO BIL …
Matched Mixtures name: … DICLOVITH-B ... DICLOVITH-B-FRT ... Diclo-B G.L. - Kapseln …
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... diclofenac and antiinfectives ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Matched Products: … Up and Up Arthritis Pain Reliever ... DICLOFENAC TEVA BV ... DICLOFENAC SODICO BIL …
Displaying drugs 826 - 850 of 1167 in total