Displaying drugs 1101 - 1125 of 1230 in total
Enalaprilat
Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Synonyms: … Enalaprilat anhydrous …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule ... of the kidney, down-regulation of this protein results in reduced blood pressure and blood fluid volume ... to overcome the limitations of the first ACE inhibitor, captopril, which had numerous side effects and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Tofogliflozin
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Synonyms: … Tofogliflozin anhydrous …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Matched Description: … Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Relebactam
Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Synonyms: … Relebactam anhydrous …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Salts name: … Relebactam sodium …
Matched Categories: … imipenem, cilastatin and relebactam …
Matched Description: … [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin ... ] to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated intra-abdominal ... [label] It is considered to be a last-line treatment option and gained FDA approval as part of the combination …
Matched Salts name: … Relebactam sodium …
Matched Categories: … imipenem, cilastatin and relebactam …
Maltose
A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical Dictionary, 5th ed).
Experimental
Investigational
Matched Synonyms: … Maltose anhydrous …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … A dextrodisaccharide from malt and starch. ... It is used as a sweetening agent and fermentable intermediate in brewing (Grant & Hackh's Chemical …
Matched Categories: … Diet, Food, and Nutrition …
Gadodiamide
Gadodiamide is a linear, non-ionic gadolinium-based contrast agent (GBCA) that is used in magnetic resonance imaging (MRI) procedures to assist in the visualization of blood vessels.[A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than nonionic iodinated contrast agents. Approved by the FDA...
Approved
Investigational
Matched Synonyms: … Gadodiamide anhydrous …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and …
Matched Description: … [A263086,A263091] GBCAs constitute the largest group of MR agents, and they are thought to be safer than ... macrocyclic or ionic GBCA, gadodiamide can potentially lead to more gadolinium retention in the brain and …
(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate
Experimental
Matched Name: … (17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate …
Matched Iupac: … cyanomethyl)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl sulfamate …
Matched Iupac: … cyanomethyl)-8-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl sulfamate …
Hydroxocobalamin
Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched Synonyms: … Hydroxocobalamin anhydrous ... Hydroxocobalaminum anhydrous …
Matched Iupac: … undecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha …
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Matched Iupac: … undecamethyl-15,20-dioxo-11,14,16-trioxa-2lambda5,9,19,26,43lambda5,44lambda5,45lambda5-heptaaza-15lambda5-phospha …
Matched Description: … Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B ... It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …
Lithium citrate
Approved
Matched Synonyms: … Anhydrous lithium citrate ... Lithium citrate (anhydrous) …
Terazosin
Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride Anhydrous …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride Anhydrous …
4-(2-Aminoethyl)Benzenesulfonyl Fluoride
Experimental
Matched Name: … 4-(2-Aminoethyl)Benzenesulfonyl Fluoride …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonyl fluoride …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonyl fluoride …
Beta-D-Glucose
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Experimental
Matched Synonyms: … Beta-D-glucose anhydrous ... Beta-D-glucose, anhydrous …
Matched Description: … It is naturally occurring and is found in fruits and other parts of plants in its free state. ... It is used therapeutically in fluid and nutrient replacement. …
Matched Description: … It is naturally occurring and is found in fruits and other parts of plants in its free state. ... It is used therapeutically in fluid and nutrient replacement. …
Dacomitinib
Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Synonyms: … Dacomitinib anhydrous …
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Fenobam
Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome).
Investigational
Matched Synonyms: … Fenobam anhydrous …
Matched Description: … Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance ... Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and …
Matched Description: … Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance ... Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and …
Cilazapril
Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. It belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat. It is branded as Inhibace in Canada and...
Approved
Matched Synonyms: … Cilazapril anhydrous …
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
Matched Description: … It is branded as Inhibace in Canada and other countries, Vascace and Dynorm in a number of European countries ... Cilazapril is an ACE inhibtor class drug used in the treatment of hypertension and heart failure. …
Matched Categories: … ACE Inhibitors and Diuretics ... cilazapril and diuretics …
CP-271485
Experimental
Matched Synonyms: … (6S)-4-Benzyl-6-(1-methyl-2,2-dioxido-1,3-dihydro-2,1-benzothiazol-5-yl)-3-morpholinone …
Florbetapir (18F)
Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to the compound florbetapir, a molecule that binds with high affinity to beta amyloid plaque, a peptide that plays a key role in Alzheimer's Disease pathogenesis. Marketed as the product Amyvid, florbetapir 18F is indicated for positron emission tomography...
Approved
Investigational
Matched Synonyms: … florbetapir-fluorine-18 …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
Matched Description: … density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and ... Florbetapir (18F) is a radiopharmaceutical compound containing the radionuclide fluorine-18 bound to ... The radionucleide fluorine-18 was chosen as it has a half life of 110 minutes allowing it to accumulate …
Matched Categories: … Fluorine Radioisotopes …
Pinacidil
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Synonyms: … Pinacidil anhydrous …
Matched Description: … peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. ... Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … pinacidil and diuretics ... Potassium Channel Opener …
Matched Description: … peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. ... Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … pinacidil and diuretics ... Potassium Channel Opener …
Canagliflozin
Canagliflozin, also known as Invokana, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise [FDA label].
It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018...
Approved
Matched Synonyms: … Canagliflozin anhydrous …
Matched Description: … Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in ... the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Categories: … Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and canagliflozin …
Matched Description: … Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in ... the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise ... It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 …
Matched Categories: … Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Alimentary Tract and Metabolism ... metformin and canagliflozin …
Loperamide oxide
Experimental
Matched Synonyms: … Loperamide oxide anhydrous …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Categories: … Alimentary Tract and Metabolism …
Flunisolide
Flunisolide (marketed as AeroBid, Nasalide, Nasarel) is a corticosteroid with anti-inflammatory actions. It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves activation of glucocorticoid receptors.
Approved
Investigational
Matched Synonyms: … Flunisolide anhydrous …
Matched Description: … It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves …
Matched Categories: … Medications that reduce magnesium levels …
Matched Description: … It is often prescribed as treatment for allergic rhinitis and its principle mechanism of action involves …
Matched Categories: … Medications that reduce magnesium levels …
Lithium hydroxide
Used for tryptophan determinations in proteins & foods.
Approved
Withdrawn
Matched Synonyms: … Lithium hydroxide anhydrous …
L-alpha-Glycerophosphorylethanolamine
Experimental
Matched Synonyms: … Ethanolamine glycerophosphate anhydrous …
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … 1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators …
Displaying drugs 1101 - 1125 of 1230 in total