Displaying drugs 2101 - 2125 of 2777 in total
Oxibendazole
Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Investigational
Vet approved
Matched Synonyms: … 5-Propoxy-2-benzimidazolecarbamic acid methyl ester …
Zinc phenolsulfonate
Approved
Experimental
Matched Synonyms: … p-hydroxybenzenesulfonic acid zinc salt …
Berdazimer
Berdazimer is a polymeric substance consisting of a polysiloxane backbone (Si-O-Si bonds) with covalently bound N-diazeniumdiolate nitric oxide (NO) donors. It releases NO through exposure to proton donors like water, which will degrade the N-diazeniumdiolate entity. Berdazimer was previously investigated as a potential treatment for molluscum contagiosum, a viral cutaneous...
Approved
Matched Synonyms: … Silsesquioxanes, 3-(2-hydroxy-1-methyl-2-nitrosohydrazinyl)propyl 3-(methylamino)propyl, polymers with silicic acid …
Matched Description: … skin discoloration, and fear and anxiety in the pediatric population. ... pediatric molluscum contagiosum, and it is the first drug to be approved for this condition. ... molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and …
Matched Description: … skin discoloration, and fear and anxiety in the pediatric population. ... pediatric molluscum contagiosum, and it is the first drug to be approved for this condition. ... molluscum contagiosum, a viral cutaneous infection mainly affecting children, sexually active adults, and …
Pyrazinamide
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Synonyms: … Pyrazinoic acid amide …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Categories: … rifampicin, pyrazinamide and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Montelukast
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Synonyms: … quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid ... quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid …
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid …
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid …
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Methylergometrine
A homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Approved
Matched Synonyms: … D-lysergic acid 1-butanolamide …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones …
Matched Categories: … Ergot Alkaloids and Derivatives ... methylergometrine and oxytocin ... Genito Urinary System and Sex Hormones …
(2R,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Experimental
Matched Synonyms: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Name: … 2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Matched Iupac: … -[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Synonyms: … 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester …
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. …
Matched Categories: … Scabicides and Pediculicides ... Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …
Ferrous gluconate
Approved
Matched Synonyms: … D-gluconic acid, iron(2+) salt (2:1) …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … ferrous gluconate and folic acid ... Blood and Blood Forming Organs …
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … ferrous gluconate and folic acid ... Blood and Blood Forming Organs …
Pemlimogene merolisbac
Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Nivolumab Versus Nivolumab Monotherapy in Participants With Advanced Adenocarcinoma of the Lung).
Investigational
Matched Synonyms: … of the lm acta protein (actan100), 5 tandem copies of a 21 amino acid fr ... monocytogenes (lm .delta.acta/.delta.inlb) expressing a fusion protein comprising the n-terminal 100 amino acids …
Matched Description: … Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study …
Matched Description: … Pemlimogene merolisbac is under investigation in clinical trial NCT03371381 (An Efficacy and Safety Study …
Pristimerin
Pristimerin is a quinone methide triterpenoid researched for its anti-cancer potential.
Investigational
Matched Synonyms: … .)-3-hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, methyl ester, …
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Synonyms: … N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-6-yl)-2-phenylmalonamic acid ... -6-{[carboxy(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Matched Iupac: … )-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … It is susceptible to gastric juice and penicillinase and may damage platelet function. …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Synonyms: … 16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid …
Matched Description: … serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
VPO-227
Investigational
Matched Synonyms: … phenyl-8-oxa-1,12,14-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-2(7),3,5,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Matched Iupac: … -8-oxa-1,12,14-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-2,4,6,10,16-pentaene-4-carboxylic acid …
Nadofaragene firadenovec
Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Matched Categories: … Cellular and Gene Therapy …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... firadenovec is formulated with an excipient (Syn-3) that facilitates gene transfer across the urothelium and ... firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human …
Matched Categories: … Cellular and Gene Therapy …
Ethiodized oil
Ethiodized oil is used by injection as a radio-opaque contrast agent. The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed oil. And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual, specific structure is unknown.
Approved
Investigational
Matched Synonyms: … IODIZED ETHYL ESTERS OF POPPYSEED FATTY ACIDS …
Matched Description: … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual ... The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed …
Matched Categories: … ethyl esters of iodised fatty acids …
Matched Description: … And although these esters are primarily as ethyl monoiodostearate and ethyl diiodostearate, the actual ... The composition of the oil is comprised of iodine combined with ethyl esters of fatty acids of poppyseed …
Matched Categories: … ethyl esters of iodised fatty acids …
Hydrogenated soybean oil
Extracted from the seeds of the soybean (Glycine soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and salad and cooking oils. According to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance. Linolenic acid and stearic acids are...
Experimental
Matched Synonyms: … Soya bean oil fatty acids, hydrogenated …
Matched Description: … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results ... salad and cooking oils. ... soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and …
Matched Description: … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results ... salad and cooking oils. ... soja), hydrogenated soybean oil is a major food fat used in the production of margarine, shortening, and …
Fish oil
Fish oil is a component of SMOFLIPID, which was FDA approved in July 2016. It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or contraindicated.
More commonly, fish oil refers to the omega-3-fatty...
Approved
Nutraceutical
Matched Synonyms: … Fish oil containing omega-3 acids …
Matched Description: … More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... EPA and DHA are ongoing. …
Matched Description: … More commonly, fish oil refers to the omega-3-fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic ... It is indicated in adults as a source of calories and essential fatty acids for parenteral nutrition ... EPA and DHA are ongoing. …
nor-NOHA
N-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).
Investigational
Matched Synonyms: … (2S)-2-amino-4-(((hydroxyamino)iminomethyl)amino)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
Matched Iupac: … (2S)-2-amino-4-(N'-hydroxycarbamimidamido)butanoic acid …
1-Methylhistidine
Experimental
Matched Synonyms: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
Matched Iupac: … (2S)-2-amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Cyclic …
N-methylnicotinamide
N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by measuring N-methylnicotinamide in the urine.
Experimental
Matched Synonyms: … Nicotinic acid methylamide …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Matched Description: … It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism ... Acids, Heterocyclic ... Nicotinic Acids …
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Oxacillin
An antibiotic similar to flucloxacillin used in resistant staphylococci infections.
Approved
Investigational
Matched Synonyms: … 6β-(5-methyl-3-phenylisoxazol-4-yl)penicillanic acid ... 5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … dimethyl-6-(5-methyl-3-phenyl-1,2-oxazole-4-amido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Pixofisiran
Investigational
Matched Synonyms: … Cotsiranib tgf-.beta.1 si-rna free acid component ... Stp-705 component tgf-.beta.1 si-rna free acid ... Tgf-.beta.1 si-rna free acid component of cotsiranib …
Displaying drugs 2101 - 2125 of 2777 in total