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Displaying drugs 2601 - 2625 of 9511 in total
Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Description: … treatment of seborrheic dermatitis in patients aged 9 years and older. ... [A251385] The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4 is ... expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of
Kaempferia galanga root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Coffea arabica seed, roasted allergenic extract is used in allergenic testing.
Approved
Colestilan is an ingredient in the EMA-withdrawn product BindRen.
Approved
Investigational
Withdrawn
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Approved
Experimental
Approved
Experimental
Glycyrrhiza glabra is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Description: … Each domain consists of 14 amino acids. ... The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid ... stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances …
Matched Categories: … combinations of sulfonamides …
Matched Products: … DORCOGLAT(R) SOLUCION OFTALMICA ... DORZOVISION(R) DORZOLAMIDA 2 % SOLUCION OFTALMICA ESTERIL …
Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Approved
Matched Mixtures name: … R-DIM® …
Matched Products: … ESPERSON (R) …
Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer, Wilsons Disease, Diabetic Macular Oedema, and Focal Segmental Glomerulosclerosis, among others. There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even...
Approved
Investigational
Matched Description: … Galactose has been used in trials studying the treatment and diagnosis of Hepatitis C, Hepatic Cancer ... rats, and Drosophila, for its association with ovarian cancer, or even for the potential treatment of ... Nevertheless, none of these ongoing studies have yet provided formal elucidation for their proposals. …
Matched Categories: … microparticles of galactose …
Approved
Matched Mixtures name: … Pain Bust R II ... Odynia-R Regular ... Dr.bro MAN OF SENSE Mans Cleanser …
Matched Products: … Miracle of Aloe Rub Roll On ... Tendinitica Synergy for treatment of Tendinitis ... Rheumatica Synergy for treatment of Rheumatitis …
Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids. It is a prodrug that is found in topical formulations used in the treatment of various conditons, such as psoriasis, acne, and sun damaged skin (photodamage).
Approved
Investigational
Matched Description: … Tazarotene, commonly marketed as Tazorac®, Avage®, and Zorac®, is member of the acetylenic class of retinoids ... It is a prodrug that is found in topical formulations used in the treatment of various conditons, such …
Matched Products: … PZORET(R) 0.05%. ( TAZAROTENE0.05% . GEL). …
Sulfacytine is a short-acting sulfonamide. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism...
Approved
Matched Description: … It inhibits bacterial synthesis of of dihydrofolic acid by preventing the condensation of the pteridine ... Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic ... However, many strains of an individual species may be resistant. …
Matched Categories: … combinations of sulfonamides …
Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 …
Matched Mixtures name: … SONDEX-OF ... R-DIM® ... GOTABIOTIC(R)F OFTALMICO …
Matched Categories: … Inducers of Drug Clearance ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … However, its usefulness is transient often because of rapid development of tolerance. ... (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. …
Matched Categories: … combinations of sulfonamides …
Matched Products: … VICLEAR(R) …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Description: … would otherwise promote narrowing of the blood vessels and lead to high blood pressure. ... Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that …
Matched Categories: … combinations of sulfonamides …
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Categories: … combinations of tetracyclines …
Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO...
Approved
Matched Description: … Erythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red ... It works by promoting the division and differentiation of committed erythroid progenitors in the bone ... glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Dasiglucagon is a glucagon analog that acts to increase blood sugar levels. It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and chemical stability in its drug formulation. In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia...
Approved
Investigational
Matched Description: … [L39190] It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted ... annually, about 7% to 25% of patients with type 2 diabetes mellitus treated with insulin experience ... Hypoglycemia is a common side effect of antidiabetic treatments, most notably insulin and sulfonylureas …
Lutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. It consists of a radionuclide, lutetium Lu-177, linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment...
Approved
Matched Description: … It consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane ... recommended lutetium Lu-177 vipivotide tetraxetan be granted marketing authorization for the treatment of
Matched Categories: … Diagnostic Uses of Chemicals …
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Approved
Investigational
Matched Description: … An important compound functioning as a component of the coenzyme NAD. ... Its primary significance is in the prevention and/or cure of blacktongue and pellagra. …
Matched Mixtures name: … Miracle Of Skin ... Miracle Of Skin ... Plalab Placenta R-20 …
Matched Products: … BK Cell 5DAYS OF SECRET SNOW WHITENING …
Displaying drugs 2601 - 2625 of 9511 in total