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Displaying drugs 2626 - 2650 of 9508 in total

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … Chloroxylenol is on the World Health Organization's List of Essential Medicines. …
Matched Products: … Clear Choice Out of Sight ... Safeguard Antibacterial Hand Wash Notes of Aloe ... Safeguard Antibacterial Hand Wash Notes of Citrus …

Penicillium roqueforti

Penicillium roqueforti is a fungus which can provoke allergic reactions. Penicillium roqueforti extract is used in allergenic testing.
Approved

Flumazenil

Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of …
Matched Products: … ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANESED-R 0.5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. ... or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions ... This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of …
Matched Products: … Esomeprazole Magnesium D/r ... Esomeprazole Magneisum D/r ... ESOZOL(R) X 20 MG CAPSULAS …

Ropeginterferon alfa-2b

Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational

Choline

A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Approved
Nutraceutical
Matched Description: … A basic constituent of lecithin that is found in many plants and animal organs. ... It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and …
Matched Mixtures name: … Harvest Of Values All B Complex Tab …

Lenalidomide

Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … exists as a racemic mixture of the active S(-) and R(+) forms. ... [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide ... referred to as immunomodulatory imide drugs (also known as cereblon modulators), which are a class of …
Matched Products: … REVLIMID(R) 5 MG ... REVLIMID(R) 10 MG ... REVLIMID(R) 15 MG …

Tretinoin

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Description: … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. ... Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin …
Matched Mixtures name: … FOLISTER COMPLEX HAIR LOTION (R) ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Products: … RETIGEL(R) 0.05% GEL ... RETICREM(R) CREMA 0.05% …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Categories: … combinations of tetracyclines ... Antiinfectives for Treatment of Acne …

Moclobemide

A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … AURORIX (R) ROCHE TABLETAS LACADAS DE 300 MG …

Xanthium strumarium pollen

Xanthium strumarium pollen is the pollen of the Xanthium strumarium plant. Xanthium strumarium pollen is mainly used in allergenic testing.
Approved
Matched Description: … Xanthium strumarium pollen is the pollen of the Xanthium strumarium plant. …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other ... [A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital …
Matched Categories: … combinations of barbiturates …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. …
Matched Categories: … combinations of sulfonamides …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Description: … using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of …
Matched Categories: … combinations of sulfonamides …

Eptotermin alfa

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Dibotermin alfa

Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Description: … Through enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of ... In a prospective clinical study of patients with an open tibial fracture, administration of dibotermin ... BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Tisagenlecleucel

Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual...
Approved
Investigational
Matched Description: … patients with relapsed or refractory B-cell precursor ALL, the overall remission rate within three months of …

Interferon alfacon-1

Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Matched Description: … The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several ... This protein has a molecular weight of 19,434 daltons. ... at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of …

Iophendylate

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Description: … A number of clinicians have published on the dangers of oil myelography. ... In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified ... Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization …
Matched Categories: … Diagnostic Uses of Chemicals …

Zinc dibutyldithiocarbamate

Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Approved
Experimental
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Robinia pseudoacacia pollen

Robinia pseudoacacia pollen is the pollen of the Robinia pseudoacacia plant. Robinia pseudoacacia pollen is mainly used in allergenic testing.
Approved
Matched Description: … Robinia pseudoacacia pollen is the pollen of the Robinia pseudoacacia plant. …

Zinc acetate

Approved
Investigational
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Gadopiclenol

Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Description: … [L43817] In 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis ... [A254002,A254017] In September 2022, the use of gadopiclenol was approved by the FDA. ... (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues …
Matched Categories: … Diagnostic Uses of Chemicals …

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Description: … . (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration …
Matched Mixtures name: … GLYCERIN OF THYMOL ... MENTOLCLARIDERM (R) ... FRICSOL (R) LINEMENTO …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Mixtures name: … FOLISTER COMPLEX HAIR LOTION (R) ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Products: … PROCORT(R) LOCIÓN CAPILAR …
Displaying drugs 2626 - 2650 of 9508 in total