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Displaying drugs 2626 - 2650 of 9613 in total
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Approved
Investigational
Matched Description: … Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections. …
Matched Categories: … Drugs for Treatment of Tuberculosis …
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … Chloroxylenol is on the World Health Organization's List of Essential Medicines. …
Matched Products: … Clear Choice Out of Sight ... Safeguard Antibacterial Hand Wash Notes of Aloe ... Safeguard Antibacterial Hand Wash Notes of Citrus …
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Description: … [A257474] It is an oxidation product in the physiological pathway of vitamin A metabolism. ... Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin …
Matched Mixtures name: … FOLISTER COMPLEX HAIR LOTION (R) ... FOLISTER COMPLEX HAIR LOTION (R) …
Matched Products: … RETIGEL(R) 0.05% GEL ... RETICREM(R) CREMA 0.05% …
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Approved
Matched Description: … benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of
Matched Products: … ANESED-R 1 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... ANESED-R 0.5 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. ... or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions ... This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of
Matched Products: … Esomeprazole Magnesium D/r ... Esomeprazole Magneisum D/r ... ESOZOL(R) X 20 MG CAPSULAS …
Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … It is listed on the World Health Organization Model List of Essential Medicines. ... table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … Plasma-Lyte R ... Normosol-R ... Normosol-R
Matched Products: … Of Nacl .9% ... Certified Nas Phys.soln Of Nacl .9% W/V B.P. …
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... [L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955. ... [L8072] It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid …
A basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Approved
Nutraceutical
Matched Description: … A basic constituent of lecithin that is found in many plants and animal organs. ... It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and …
Matched Mixtures name: … Harvest Of Values All B Complex Tab …
Streptococcus pneumoniae type 18c capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 18c of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 18c of
A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Categories: … combinations of tetracyclines …
Lenalidomide (previously referred to as CC-5013) is an immunomodulatory drug with potent antineoplastic, anti-angiogenic, and anti-inflammatory properties. It is a 4-amino-glutamyl analogue of thalidomide and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. However, lenalidomide is much safer and potent than thalidomide, with...
Approved
Matched Description: … exists as a racemic mixture of the active S(-) and R(+) forms. ... [A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide ... referred to as immunomodulatory imide drugs (also known as cereblon modulators), which are a class of
Matched Products: … REVLIMID(R) 5 MG ... REVLIMID(R) 10 MG ... REVLIMID(R) 15 MG …
Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Categories: … combinations of tetracyclines ... Antiinfectives for Treatment of Acne …
A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide is more efficacious than placebo medication and similarly efficacious as tricyclic antidepressants (TCA) or selective serotonin reuptake inhibitors (SSRIs)....
Approved
Investigational
Matched Description: … Most meta-analyses and most studies indicate that in the acute management of depression, moclobemide …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … AURORIX (R) ROCHE TABLETAS LACADAS DE 300 MG …
Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other ... [A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital …
Matched Categories: … combinations of barbiturates …
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. …
Matched Categories: … combinations of sulfonamides …
Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Description: … using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of
Matched Categories: … combinations of sulfonamides …
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Description: … Through enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of ... In a prospective clinical study of patients with an open tibial fracture, administration of dibotermin ... BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immunocellular therapy that involves autologous T cells that are collected from each individual...
Approved
Investigational
Matched Description: … patients with relapsed or refractory B-cell precursor ALL, the overall remission rate within three months of
Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon. The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several natural interferon alpha subtypes and assigning the most frequently observed amino acid in each corresponding position. Four additional amino acid changes were made to facilitate the...
Approved
Investigational
Matched Description: … The 166-amino acid sequence of Interferon alfacon-1 was derived by scanning the sequences of several ... This protein has a molecular weight of 19,434 daltons. ... at 20/166 amino acids (88% homology), and comparison with interferon-beta shows identity at over 30% of
Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Description: … A number of clinicians have published on the dangers of oil myelography. ... In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified ... Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization …
Matched Categories: … Diagnostic Uses of Chemicals …
Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Approved
Experimental
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Approved
Investigational
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Description: … [L43817] In 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis ... [A254002,A254017] In September 2022, the use of gadopiclenol was approved by the FDA. ... (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues …
Matched Categories: … Diagnostic Uses of Chemicals …
Displaying drugs 2626 - 2650 of 9613 in total