Advanced Filter

Filter by Group

Filter by Market Availability

Displaying drugs 251 - 275 of 15549 in total
Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent.
Approved
Investigational
Matched Synonyms: … Granulocyte colony stimulating factor 3 (CHO cell derived) …
Matched Description: … Lenograstim is a recombinant granulocyte colony-stimulating factor used as an immunostimulating agent …
Matched Products: … GRANOCYTE 34 FOR INJECTION 263 mcg/ml …
Omaveloxolone (RTA-408) is a semisynthetic oleanane triterpenoid with antioxidant and anti-inflammatory properties.[A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity...
Approved
Investigational
Matched Synonyms: … Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro- …
Matched Description: … [A257529] In February 2023, omaveloxolone was approved by the FDA for the treatment of Friedreich's ataxia ... In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 ... Therefore, the use of Nrf2 activators such as omaveloxolone represents a therapeutic advantage in this …
Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved
Matched Synonyms: … -3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide ... (4S,4aS,5aR,12aS)-9-(2-(tert-butylamino)acetamido)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro …
Matched Iupac: … -dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide ... (4S,4aS,5aR,12aS)-9-[2-(tert-butylamino)acetamido]-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11 …
Matched Description: … Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil ... It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … TIGECLIN ® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE. ... TIGECICLINA 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... TIGEVITAE® 50 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor. DB00135 is a non-essential amino acid with a polar side group. N-acetyltyrosine is administered as parenteral nutrition or intravenous infusion due to its enhanced solubility compared to tyrosine . It is typically administered as a...
Approved
Matched Synonyms: … (2s)-2-acetylamino-3-(4-hydroxyphenyl)propanoic acid ... (+)-(2s)-2-(acetylamino)-3-(4-hydroxyphenyl)propanoic acid ... Melanowhite-A
Matched Iupac: … (2S)-2-acetamido-3-(4-hydroxyphenyl)propanoic acid …
Matched Description: … N-acetyltyrosine, also referred to as N-acetyl-L-tyrosine, is used in place of as a tyrosine precursor ... [DB00135] is a non-essential amino acid with a polar side group. ... It is typically administered as a source of nutritional support where oral nutrition is inadequate or …
Matched Mixtures name: … AMINOPLASMAL-5% E INFUSION ... AMINOPLASMAL-10% E INFUSION ... Aminosyn II in Dextrose …
Ombitasvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Synonyms: … -(4-tert-butylphenyl)pyrrolidine-2,5-diyl]bis{(4,1-phenylene)carbamoyl(2S)pyrrolidine-2,1-diyl[(2S)-3- …
Matched Iupac: … ]-3-methylbutanoyl]pyrrolidine-2-amido]phenyl}pyrrolidin-2-yl]phenyl}carbamoyl)pyrrolidin-1-yl]-3-methyl ... -1-oxobutan-2-yl]carbamate ... methyl N-[(2S)-1-[(2S)-2-({4-[(2S,5S)-1-(4-tert-butylphenyl)-5-{4-[(2S)-1-[(2S)-2-[(methoxycarbonyl)amino …
Matched Description: … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. ... Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development …
Matched Categories: … Treatments for Hepatitis C ... Hepatitis C Virus NS5A Inhibitor ... Antivirals for Systemic Use ... Antiinfectives for Systemic Use ... Antivirals for treatment of HCV infections …
An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Approved
Investigational
Matched Synonyms: … 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone ... (4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene …
Matched Description: … An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer …
Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion. It is available as vaginal suppositories and also used in combination with the antiprogestin and mifepristone for termination of 1st- and 2nd-trimester pregnancy . It is not FDA-approved but available in...
Approved
Withdrawn
Matched Synonyms: … 16,16-Dimethyl-trans-delta-2-PGE1 methyl ester ... 16,16-Dimethyl-trans-delta(sup 2)-prostaglandin E1 methyl ester …
Matched Iupac: … methyl (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4,4-dimethyloct-1-en-1-yl]-5-oxocyclopentyl] ... hept-2-enoate …
Matched Description: … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the ... for termination of 1st- and 2nd-trimester pregnancy [A19726]. ... It is not FDA-approved but available in Japan marketed as Preglandin. …
Matched Categories: … Prostaglandins E ... Prostaglandins E, Synthetic …
Approved
Matched Synonyms: … Haemagglutinin-strain A (H5N1) …
Matched Name: … Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated) …
Matched Categories: … Inactivated Influenza A Virus Vaccine …
Matched Products: … Pandemic Influenza Vaccine H5N1 Baxter Suspension for Injection …
Paroxetine is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Paxil. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others. It was approved by the FDA in the early 1990s and marketed by SmithKline...
Approved
Investigational
Matched Synonyms: … (3S-trans)-3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine ... (−)-(3S,4R)-4-(p-fluorophenyl)-3-((3,4-(methylenedioxy)phenoxy)methyl)piperidine …
Matched Iupac: … (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine …
Matched Description: … [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition ... Paroxetine is well tolerated in most patients with a similar adverse effect profile to other members ... [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. …
Matched Salts cas: … 217797-14-3
Matched Categories: … Antidepressive Agents Indicated for Depression …
Matched Products: … Seroxat 2 mg/ml - Suspension zum Einnehmen …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Matched Iupac: … -8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato …
Matched Description: … Ceftazidime was approved by the FDA on July 19, 1985, and is currently available either alone or in ... Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which ... antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in
Matched Salts cas: … 78439-06-2 ... 73547-61-2
Matched Mixtures name: … CEFAZIME FOR INJECTION 1 g/vial ... ZAVİCEFTA 2 G/0.5 G İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 10 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … FORTUM FOR INJECTION 2 g/vial ... Kefazim 2 g Trockenstechampulle ... CEFTAZIDIME KABI POWDER FOR SOLUTION FOR INJECTION 2G/VIAL …
Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … There is no specific treatment for hepatitis. ... either as a co-infection or super-infection in a HBsAg carrier. ... It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. …
Matched Mixtures name: … Hexaxim Suspension for Injection …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 10mcg/0.5ml ... ENGERIX-B ERİŞKİN 20 MCG/ 1ML ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 3 DOZ …
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Iupac: … (2S)-2-[(2-{[(2S)-1-hydroxybutan-2-yl]amino}ethyl)amino]butan-1-ol …
Matched Description: … [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of ... [L31743] Ethambutol was first described in the literature in 1961. ... Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], …
Matched Categories: … Antiinfectives for Systemic Use ... Drugs for Treatment of Tuberculosis …
Matched Products: … E-BUTOL TABLET 400 mg …
A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of inflammatory disorders and cancers. Thalidomide displays immunosuppressive and anti-angiogenic activity through modulating the release of inflammatory mediators like tumor necrosis factor-alpha...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindoline ... 3-Phthalimidoglutarimide ... 2,6-dioxo-3-phthalimidopiperidine …
Matched Iupac: … 2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione …
Matched Description: … It has been reintroduced and used for a number of inflammatory disorders and cancers. ... severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enrol in ... A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, thalidomide was withdrawn …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver. Prednisone was granted FDA approval on 21 February 1955.
Approved
Vet approved
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-7,10-dione ... (1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH …
Matched Description: … A synthetic anti-inflammatory glucocorticoid derived from [cortisone]. ... [A187463] It is biologically inert and converted to [prednisolone] in the liver. …
Matched Categories: … Medications that reduce magnesium levels ... Corticosteroids for Systemic Use ... Corticosteroids for Systemic Use, Plain …
Matched Products: … ROMEZON DR 2 MG TABLET, 30 ADET …
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Synonyms: … α-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide …
Matched Iupac: … N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide …
Matched Description: … with a daily dosage of 300 mg or more and typically occurred in the first four weeks of therapy". ... chronic myeloid leukemia, in 2001. ... [A249305] It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. …
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … [A254157] A phase 3 clinical trial (NCT02879305) found that in patients with CKD undergoing dialysis, ... [A254172] In June 2020, daprodustat was first approved in Japan for the treatment of renal anemia. ... Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that …
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Description: … Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Approved
Matched Iupac: … trilithium(1+) 2-hydroxypropane-1,2,3-tricarboxylate …
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-2-amino-3-mercapto-3-methylbutanoic acid ... 3-mercapto-D-valine …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Matched Description: … Penicillamine is a pharmaceutical of the chelator class. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate ... Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate ... (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl …
Matched Description: … Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor ... Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast …
Matched Categories: … Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Approved
Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994. It can effectively manage acute pain as well as pain related to rheumatic diseases, and has a well studied adverse effect profile. Given its...
Approved
Vet approved
Matched Synonyms: … (+)-2-(6-Methoxy-2-naphthyl)propionic acid ... (+)-2-(Methoxy-2-naphthyl)-propionsäure ... (+)-2-(Methoxy-2-naphthyl)-propionic acid …
Matched Iupac: … (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid …
Matched Description: … prescription use in 1976 and then for over-the-counter (OTC) use in 1994. ... for a variety of clinical situations requiring analgesia. ... Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for
Matched Salts cas: … 26159-34-2
Matched Mixtures name: … DAFLOXEN F ... All Night Pain Relief PM ... All Day Sinus and Cold D …
Matched Categories: … Non COX-2 selective NSAIDS ... Topical Products for Joint and Muscular Pain ... Antiinflammatory Products for Vaginal Administration ... Antiinflammatory Preparations, Non-Steroids for Topical Use …
Matched Products: … Naproxen All day relief for pain ... Naproxen Caplets All day relief for pain ... NAPROXENO 3 % …
Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690]. ... , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON 2 mg powder and solvent for prolonged-release suspension for injection ... BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …
The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced bioavailability in the treatment of dyslipidemia. The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free fatty acids as opposed to other products whose form is as ethyl...
Approved
Investigational
Matched Synonyms: … Omega-3-carboxylic acids …
Matched Name: … Omega-3-carboxylic acids …
Matched Description: … The omega-3 carboxylic acid (OM3-CA) is a new formulation of omega-3 fatty acids that present an enhanced ... The increased bioavailability is explained because OM3-CA is found in a form of polyunsaturated free ... acid as the most abundant species found in a proportion of 55% and 20% respectively. …
Matched Categories: … Fatty Acids, Omega-3
Colloidal oatmeal is produced by grinding fine granules of oatmeal and boiling it to extract the colloidal material. It contains high concentrations of starches and beta-glucan that exhibits water-absorbing properties. Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities, as well as UV-absorbing activity. Colloidal oatmeal...
Approved
Nutraceutical
Matched Description: … It is available in topical products as a skin soothing agent. ... Colloidal oatmeal is a FDA-approved skin protectant that temporarily protects and helps relieve minor ... Phenols are also contained in colloidal oatmeal, which possess antioxidant and anti-inflammatory activities …
Matched Mixtures name: … Infinite Aloe All-IN-one Skin Care ... Pediadermics Eczema 3
Matched Products: … 3-In-1 Relief CVS ... A Bit Hippy ... TMC-A Hair Tonic …
Displaying drugs 251 - 275 of 15549 in total