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Displaying drugs 251 - 275 of 12791 in total

Tolcapone

Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication. It is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity.
Approved
Withdrawn

Glucagon

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.[L7634,L7637,L7640,L7643,L8519] Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.[L7640,L7643] Glucagon was granted FDA...
Approved
Matched Description: … Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Simeprevir

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United...
Approved
Matched Description: … acid position of 168 also results in higher treatment failure rates [A19630]. ... therapeutic efficacy of the drug is observed with NS3 Q80K polymorphic variants and simeprevir-specific amino …

Ethyl macadamiate

Ethyl macadamiate is derived from Macadamia terifolia seed oil. It is a non-volatile ester of ethyl alcohol and the fatty acids. Ethyl macadamiate is used in cosmetics and personal care products such as sunscreen, hair care products and skin care products as an emollient and skin conditioning agent.
Approved
Matched Description: … Ethyl macadamiate is used in cosmetics and personal care products such as sunscreen, hair care products …

Peanut oil

Peanut oil is derived from Arachis hypogaea which can be found in South America, Mexico, and Centro America. The kernels are consumed roasted but a large percentage is used for the production of vegetable oil. The peanut oil represents about 45-52% of the kernel content and it is mainly formed...
Approved

Tigecycline

Tigecycline is a glycylcycline antibiotic developed and marketed by Wyeth under the brand name Tygacil. It was developed in response to the growing prevalence of antibiotic resistance in bacteria such as Staphylococcus aureus. It was granted fast-track approval by the U.S. Food and Drug Administration (FDA) on June 17, 2005.
Approved

Tyrothricin

Tyrothricin is an antibiotic peptide complex produced and extracted from the aerobic Gram-positive bacillus Brevibacillus parabrevis [L4019, L4021, A32851] which was previously categorized as Bacillus brevis and Bacillus aneurinolyticus . This complex is a mixture comprised of 60% tyrocidine cationic cyclic decapeptides (consisting largely of the six predominant tyrocidines, TrcA/A1,...
Approved
Matched Categories: … Amino Acids, Peptides, and Proteins …

Magnesium hydroxide

Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially...
Approved
Investigational
Matched Mixtures name: … Mi Acid ... Mi Acid ... Mi Acid …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …

Levocarnitine

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Approved
Investigational
Matched Categories: … Amino Acids and Derivatives …

Acetylcarnitine

Acetylcarnitine is an investigational drug in the United states, Italy, United Kingdom, China, Israel, and Norway, and it is approved in Italy, Portugal, Argentina, Chile, Philippines, Australia, and India. Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans. In human plasma and tissues,...
Approved
Investigational
Matched Description: … plasma and tissues, acetylcarnitine is the most predominant acylated ester of carnitine, which is an amino ... acid derivative that is made in the kidney, liver, and brain from lysine and methionine. ... role of acetylcarnitine is to help transport fatty acids into the mitochondrial matrix where fatty acid …

Thyrotropin alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating ... heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino ... acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing …

Sesame seed

Sesame seed allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Hair Oil …

Bos taurus skin

Bos taurus skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Cattle Hair and Epithelia …

Coffee bean

Coffee bean allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Hair Boost …

Sus scrofa skin

Sus scrofa skin or pelt is used in allergenic testing.
Approved
Matched Mixtures name: … Hog Hair and Epithelia …

Dihydro-alpha-ergocryptine

Alpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. Both compounds are hydrogenated ergot derivatives. Alpha-dihydroergocryptine approved drug product...
Approved
Matched Description: … This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine …

Potassium citrate

Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste. It contains 38.3% potassium by mass. In the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat...
Approved
Investigational
Vet approved
Matched Description: … Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. …
Matched Mixtures name: … Potassium Citrate-Citric Acid ... Potassium Citrate-Citric Acid ... Potassium Citrate and Citric Acid …
Matched Categories: … Citric Acid Derivatives …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid …
Matched Description: … tryptophan covalently bonded to decanoic acid. ... and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... [A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Pepsin

Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products . Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid, causes nutrients including meat or coagulated...
Approved
Experimental
Investigational
Matched Description: … digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence of stomach acid …
Matched Mixtures name: … Glutamic Acid Hydrochloride Nu Life ... Glutamic Acid HCl Betaine HCl W Pepsin ... Glutamic Acid Pepsin and Betaine Tablets …
Matched Categories: … Aspartic Acid Proteases ... Aspartic Acid Endopeptidases ... pepsin and acid preparations …

Taliglucerase alfa

Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, β-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Approved
Investigational

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …

Lyme disease vaccine (recombinant OspA)

Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Description: … Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the …

Liotrix

Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Iupac: … disodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate (2S)-2-amino-3-[ …
Matched Categories: … Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic ... Amino Acids, Peptides, and Proteins …

Zinc sulfate, unspecified form

Zinc sulfate is a common zinc supplement in parenteral nutrition.[A216916,L12888]
Approved
Experimental
Matched Mixtures name: … Aqua De Folli Hair Booster ... Aqua De Folli Hair Booster Pro ... Aqua De Folli Hair Booster Mini …

Pyridoxine

Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid. ... is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino ... and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid …
Matched Mixtures name: … Anti White Hair Essence ... Folic Acid Plus ... B6, B12 & Folic Acid …
Displaying drugs 251 - 275 of 12791 in total