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Did you mean bitopertin of rp 493838 of r 168 of ビトペルチン?
Displaying drugs 2851 - 2875 of 9508 in total

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … [L8417] One unique property of this drug is that it does not increase gastric acid secretion. ... gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Description: … Yohimbine has been used as a mydriatic and in the treatment of impotence. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Resorcinol

Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Matched Description: … Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. ... It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin ... possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of …

Relatlimab

Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...
Approved
Investigational
Matched Description: … a variety of cancers, including leukemia[A246160] and melanoma. ... inhibitor [nivolumab] in the combination product Opdualag (Bristol-Myers Squibb), for the treatment of ... anti-LAG-3 antibody, entering clinical trials in 2013,[A246155] and has garnered interest in the treatment of …

Piperonyl butoxide

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as...
Approved
Vet approved
Matched Description: … It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates ... Piperonyl butoxide is a semisynthetic derivative of safrole. ... It is used for the treatment of head, pubic (crab), and body lice. …
Matched Mixtures name: … R & C Shampoo With Conditioner …

Octasulfur

Sulfur is a chemical element that is present in all living tissues. The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). After calcium and phosphorus, it is the third most abundant mineral in the human body. Sulfur is also found in garlic, onions and broccoli. People take sulfur...
Approved
Matched Description: … People take sulfur by mouth for shortness of breath, allergies, swelling in the back of the throat (pharyngitis ... The most commonly used form of pharmaceutical sulfur is Octasulfur (S8). …
Matched Mixtures name: … Sulfacet-R ... Sulfacet R Lotion …

Vilanterol

Vilanterol is a selective long-acting β2-adrenergic agonist (LABA) with inherent 24-hour activity for the once-daily treatment of COPD and asthma. This is in response to the need for longer-acting β2-adrenergic agonists to overcome poor patient compliance (due to the frequency of dosing regimens or complexities of drug administration). Vilanterol was...
Approved
Matched Description: … salmeterol modification by modifying the salmeterol molecule to create homochiral compounds with the (R) ... of the release of hypersensitivity mediators from mast cells in the lungs. ... dosing regimens or complexities of drug administration). …

Rice bran oil

Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It contains monosaturated fatty acids, polyunsaturated fatty acids, and saturated fatty acids. The major constituents of rice bran oil include myristic...
Approved
Matched Description: … The major constituents of rice bran oil include myristic acid, palmitic acid, stearic acid, oleic acid ... Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature …

Regdanvimab

Regdanvimab (CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. It blocks the interaction between viral spike proteins and angiotensin-converting enzyme 2 (ACE2) that allows for viral entry into the cell, thereby inhibiting the virus' ability to replicate. Trials...
Approved
Investigational
Matched Description: … Trials investigating the use of regdanvimab as a therapeutic candidate for the treatment of COVID-19 ... CT-P59) is a recombinant human IgG1 monoclonal antibody directed at the receptor binding domain (RBD) of …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … ; the promotion of urinary excretion of toxic substances; as an Antiglaucoma agent; and as a renal function ... Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including ... On October 30, 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of …

Castor oil

Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … Castor oil is a rich source of [DB02955], which represents up to 90% of the total castor oil content. ... Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (_Ricinus communis ... Castor oil was mainly used in the manufacturing of soaps, lubricants, and coatings [A31170]. …

Cabergoline

Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Aminophylline

Aminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma,...
Approved
Matched Description: … Similar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as ... The majority of aminophylline medications are discontinued and the remaining medications on the market …
Matched Categories: … combinations of xanthines …

Iloperidone

Iloperidone is a benzisoxazole and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. It is considered to be a second-generation antipsychotic drug with multiple receptor binding profile, although it shows high affinity towards 5-HT2A and dopamine D2 receptors. Iloperidone is currently used to...
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Temsirolimus

Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). It was developed by Wyeth Pharmaceuticals under the trade name Torisel. Temsirolimus was approved by the FDA in late May 2007 as well as the European Medicines Agency (EMEA) on November 2007.
Approved
Matched Description: … Temsirolimus is a derivative of sirolimus used in the treatment of renal cell carcinoma (RCC). …
Matched Categories: … Mammalian target of rapamycin (mTOR) kinase inhibitors …

Voxilaprevir

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat ... nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of ... Vosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, …
Matched Categories: … Antivirals for treatment of HCV infections …

Rescinnamine

Rescinnamine is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. It is an alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia.
Approved
Matched Description: … It is an alkaloid obtained from _Rauwolfia serpentina_ and other species of _Rauwolfia_. …

Rainbow trout

Rainbow trout allergenic extract is used in allergenic testing.
Approved

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … C is the isomer of neomycin B, making these two stereoisomers the active components of neomycin. ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of …
Matched Mixtures name: … SONDEX-OF ... CLONODEX (R) …

Desloratadine

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Description: … It is the active descarboethoxy metabolite of loratidine (a second generation histamine). …
Matched Products: … DESINISTA(R)5 MG TABLETAS …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of ... 2017, a combination antibacterial therapy under the market name vabomere was approved for treatment of …

Repotrectinib

Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Description: … [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ... ROS1 G2032R is responsible for 50 to 60% of [crizotinib]-resistant cases. ... next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of …

Carbamazepine

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … [A180301] Aside from the above uses, this drug is also given to control the symptoms of bipolar 1. …
Matched Categories: … Inducers of Drug Clearance ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Difluocortolone

Difluocortolone is a potent topical corticosteroid. It is commonly used in dermatology for the reduction of inflammation and itching. It was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.
Approved
Investigational
Withdrawn
Matched Description: … It is commonly used in dermatology for the reduction of inflammation and itching. …
Displaying drugs 2851 - 2875 of 9508 in total