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Displaying drugs 2876 - 2900 of 3361 in total

Eribulin

Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of...
Approved
Investigational
Matched Description: … Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. ... Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer ... who have previously received at least two chemotherapeutic regimens for the treatment of metastatic …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Halaven Solution for Injection 0.5mg/mL ... HALAVEN 0.5 mg/ml solution for injection …

Technetium Tc-99m sulfur colloid

Technetium 99m sulfur colloid is a radiopharmaceutical diagnostic agent used in the evaluation of various conditions including lymph node metastases in breast cancer, detection of shunt patency, imaging of reticuloendothelial cells for assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. Following injection or oral administration, single...
Approved
Investigational
Matched Description: … assessment of liver function, and studies of esophageal transit and gastroesophageal reflux. ... Depending on site of administration and intended usage, Technetium 99m sulfur colloid enters the capillaries ... and is transported to the lymph nodes (subcutaneous injection), mixes with peritoneal fluid (intraperitoneal …
Matched Categories: … Indicators and Reagents ... Hepatic and Reticulo Endothelial System ... Technetium (99Mtc), Particles and Colloids …
Matched Products: … Kit for the Prepartion of Technetium Tc99m Sulfur Colloid ... Kit for the Preparation of Technetium Tc 99m Sulfur Colloid …

8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine

Experimental
Matched Name: … 8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine …

(1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL

Experimental
Matched Name: … (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL …
Matched Iupac: … (2R,3R,4R)-1H,2H,3H,4H-benzo[c]phenanthrene-2,3,4-triol …

Liraglutide

Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer ... A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … solution for injection in pre-filled pen 6mg/ml ... SOLUTION FOR INJECTION IN PRE-FILLED PEN 6MG/ML ... VICTOZA 6MG/ML SOLUTION FOR INJECTION IN PRE-FILLED PEN …

Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)

Approved
Investigational
Matched Mixtures name: … Tetanus and Diphtheria Toxoids Adsorbed for Adult Use ... Diphtheria and Tetanus Toxoids Adsorbed ... Tetanus and Diphtheria Toxoids Adsorbed …
Matched Categories: … Antiinfectives for Systemic Use …
Matched Products: … Diphtheria Toxoid for Reaction Test 0.2lf/ml ... Diphtheria Toxoid for Schick Control 0.2lf/ml …

Malathion

Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Approved
Investigational
Matched Synonyms: … [(dimethoxyphosphinothioyl)thio]butanedioic acid diethyl ester …
Matched Description: … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity. ... Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides, Insecticides and Repellents …

Anastrozole

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Description: … provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and ... drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and ... [A186877,A186955] Anastrozole was first approved for use in the United States in 1995.[L8863] …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ANASTROZOL ACINO 1MG …

Mitomycin

Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of Streptomyces caespitosus.[L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations, RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. Few other antibiotics have been...
Approved
Matched Description: … [L12867,A193419] It is an alkylating agent that inhibits DNA synthesis (and, at higher concentrations ... , RNA and protein synthesis) by cross-linking the complementary strands of the DNA double helix. ... of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper Tract …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Antineoplastic and Immunomodulating Agents ... Indicators and Reagents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MITONCO 10mg powder for solution for injection/infusion or intravesical ... Mitomycin for Injection ... Mitomycin for Injection USP …

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … ICUNES® 100mcg/ml Concentrate for Solution for Infusion ... PRECEDEX CONCENTRATE FOR SOLUTION FOR INFUSION 100 mcg/ml (Vial) ... Dexmedetomidine Hydrochloride for Injection …

Eculizumab

Eculizumab is a monoclonal antibody that targets complement protein C5.[L6919,A2245] Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.[L6919,A2245,A2246] Eculizumab was granted FDA approval on 16 March 2007. In Q1 2023, the EMA's Committee for Medicinal Products...
Approved
Investigational
Matched Description: … [L6919] In Q1 2023, the EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a positive ... opinion of two formulations of eculizumab indicated for the treatment of paroxysmal nocturnal hemoglobinuria …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Soliris Concentrate for Solution for Infusion 300mg/vial …

Doripenem

Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … ,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … to reiterate its safety and efficacy for its approved indications. ... Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Powder for Injection 500mg ... DORIBAX 500 MG (Doripenem) for Injection …

Betaine

Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Acidol …
Matched Description: … The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment ... occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and ... A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Betaine HCl and Pepsin ... Rocky Mountain Multiple Vit and Min Mega Tab …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Acid Preparations …
Matched Products: … Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Iupac: … methoxy)ethoxy]ethyl}carbamoyl)methoxy]ethoxy}ethyl)carbamoyl]-1-carboxypropyl]carbamoyl}heptadecanoic acid …
Matched Description: … The use of salt forms of semaglutide, including semaglutide sodium and semaglutide acetate, has not been ... Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December ... and reducing blood glucose. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen …

Romiplostim

Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Description: … Each domain consists of 14 amino acids. ... The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid ... Interestingly, romiplostim's amino acid sequence is not similar to that of endogenous thrombopoietin. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Intercellular Signaling Peptides and Proteins …
Matched Products: … ROMIPLATE POWDER FOR SOLUTION FOR INJECTION 250 ?g/vial …

Glyceryl 1-oleate

Experimental
Matched Synonyms: … 9-Octadecenoic acid, 2,3-dihydroxypropyl ester …

Danavorexton

Investigational
Matched Synonyms: … 1-piperidinecarboxylic acid, 3-((methylsulfonyl)amino)-2-(((cis-4-phenylcyclohexyl)oxy)methyl)-, methyl …

Zinc mesoporphyrin

Investigational
Matched Synonyms: … 21h,23h-porphine-2,18-dipropanoic acid, 7,12-diethyl-3,8,13,17-tetramethyl-, zinc complex …

Fulvestrant

Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Description: … It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and ... While it is used as monotherapy for the treatment of breast cancers, it is also used in combination with ... [alpelisib] for the treatment of HR-positive, human epidermal growth factor receptor 2 (HER2)-negative …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FASLODEX SOLUTION FOR INJECTION 250MG/5 ML ... FEMCORD SOLUTION FOR INJECTION 250 MG/5 ML ... Faslodex Solution For Injection 250 mg/5ml …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting ... neurological, physical, and cognitive effects. ... Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Experimental Unapproved Treatments for COVID-19 ... Sphingosine 1-phosphate Receptor Modulator ... Sphingosine 1 Phosphate Receptor Modulators ... Sphingosine-1-phosphate (S1P) receptor modulators …
Matched Products: … GILENYA ® 0.5 MG CAPSULA DURA …

Insulin degludec

Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, ... Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused ... [A18561,A18562,A18563,A18564,A174934] As a result, people with T1D rely primarily on exogenous forms …
Matched Mixtures name: … Ryzodeg® FlexTouch® 100 U/ml Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Tresiba® FlexTouch® 100 U/ml Solution for Injection ... Tresiba ® FlexTouch® 100 U/ml Solution for Injection ... Tresiba ® Flextouch® 200 U/mL Solution for Injection …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Description: … [F136] It was developed by Merck & Co and first approved for the treatment of metastatic malignant melanoma ... as interchain bonds and 23 interchain bonds. ... [A18829] It contains 32 cysteine residues and the complete folded molecule includes 4 disulfide linkages …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … KEYTRUDA SOLUTION FOR INFUSION 25MG/ML ... Keytruda 100mg Solution for Infusion …

Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for ... Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical ... humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … Taltz 80mg solution for injection in pre-filled pen ... TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/ml ... Taltz 80mg solution for injection in pre-filled syringe …

5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate

Experimental
Matched Name: … 5-(6-Amino-9h-Purin-9-Yl)-4-Hydroxytetrahydrofuran-3-Yl Dihydrogen Phosphate …
Matched Iupac: … {[(3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid …

Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

Experimental
Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …
Displaying drugs 2876 - 2900 of 3361 in total