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Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … Levomefolic acid ... (6S)-5-Methyltetrahydrofolic acid ... 5-methyl-(6S)-tetrahydrofolic acid
Matched Name: … Levomefolic acid
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... Supplementation of levomefolic acid is desired over folic acid due to reduced potential for masking vitamin ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate …
Matched Mixtures name: … Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Synonyms: … Fucidin acid ... Fusidic acid
Matched Name: … Fusidic acid
Matched Iupac: … dihydroxy-3a,3b,6,9a-tetramethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-ylidene]-6-methylhept-5-enoic acid
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... AXCEL FUSIDIC ACID-B CREAM …
Matched Salts name: … Fusidic acid hemihydrate …
Matched Categories: … fusidic acid ... fusidic acid ... fusidic acid ... fusidic acid
Matched Products: … FUSIDIC ACID ... Taro-fusidic Acid ... AXCEL FUSIDIC ACID CREAM …
Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Synonyms: … Pentetic acid ... Diethylene triamine pentaacetic acid ... Diethylenetriamine pentaacetic acid
Matched Name: … Pentetic acid
Matched Iupac: … 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetic acid
Matched Description: … acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ... Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. …
Matched Products: … Pentetic Acid
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … Bile acid sequestrants like colestipol have been in use since the 1970s. ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... , colestipol is still generally only employed as an adjunct therapy and the relatively physical nature …
Matched Salts name: … Colestipol hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Colestipol Hydrochloride ... Colestipol hydrochloride
Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional group. It is a white solid with a disagreeable odor. Because it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries...
Approved
Matched Synonyms: … -TOLUIC ACID ... α-toluic acid ... -PHENYLACETIC ACID
Matched Name: … Phenylacetic acid
Matched Iupac: … 2-phenylacetic acid
Matched Description: … Phenylacetic acid is an organic compound containing a phenyl functional group and a carboxylic acid functional ... manufacture of substituted amphetamines), it is subject to controls in countries including the United States and
Matched Mixtures name: … Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate ... Sodium Phenylacetate and Sodium Benzoate …
Matched Categories: … Alimentary Tract and Metabolism ... sodium benzoate and sodium phenylacetate ... Various Alimentary Tract and Metabolism Products …
Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Synonyms: … Dehydrocholic acid ... 3,7,12-triketocholanic acid ... 3,7,12-trioxocholanic acid
Matched Name: … Dehydrocholic acid
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve...
Approved
Matched Synonyms: … Deoxycholic acid ... Desoxycholic acid ... 7α-deoxycholic acid
Matched Name: … Deoxycholic acid
Matched Iupac: … 9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Matched Description: … Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and ... In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic ... appearance and reduce facial fullness or convexity. …
Matched Categories: … deoxycholic acid ... Bile Acids and Salts ... Cholagogues and Choleretics …
One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Approved
Nutraceutical
Matched Synonyms: … Aspartic acid ... L-Aspartic acid ... 2-Aminosuccinic acid
Matched Name: … Aspartic acid
Matched Iupac: … (2S)-2-aminobutanedioic acid
Matched Description: … It is found in animals and plants, especially in sugar cane and sugar beets. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... Premasol - sulfite-free (Amino Acid) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Synonyms: … Etidronic acid ... Acetodiphosphonic acid ... (1-Hydroxyethylene)diphosphonic acid
Matched Name: … Etidronic acid
Matched Iupac: … (1-hydroxy-1-phosphonoethyl)phosphonic acid
Matched Description: … ], [ibandronic acid], [minodronic acid], and [risedronic acid]. ... Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and
Matched Categories: … etidronic acid and calcium, sequential ... etidronic acid ... Drugs Affecting Bone Structure and Mineralization …
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins …
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Synonyms: … Stearic acid ... Octadecoic acid ... Octadecanoic acid
Matched Name: … Stearic acid
Matched Iupac: … octadecanoic acid
Matched Description: … acids that comes from many animal and vegetable fats and oils. ... Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals or a granular crystalline powder. It is considered generally recognized as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and flavoring agent. Its use as a food...
Approved
Vet approved
Matched Synonyms: … Propionic acid
Matched Name: … Propanoic acid
Matched Iupac: … propanoic acid
Matched Description: … as safe (GRAS) food ingredient by FDA, where it acts as an antimicrobial agent for food preservation and ... Sodium propionate is is prepared by neutralizing propionic acid with sodium hydroxide. ... Sodium propionate is the sodium salt of propionic acid that exists as colorless, transparent crystals …
Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Synonyms: … Mycophenolic acid ... (e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Matched Name: … Mycophenolic acid
Matched Iupac: … (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
Matched Description: … [A249180] However, mycophenolic acid treatment is more expensive and requires therapeutic drug monitoring ... and antiviral properties. ... to optimize efficacy and minimize toxicity. …
Matched Categories: … Mycophenolic Acid and Prodrugs ... mycophenolic acid ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Mycophenolic Acid ... Apo-mycophenolic Acid ... Mar-mycophenolic Acid
Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Approved
Withdrawn
Matched Synonyms: … Canrenoic acid
Matched Name: … Canrenoic acid
Matched Iupac: … ,15S)-14-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien-14-yl]propanoic acid
Matched Description: … Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Glycyrrhizic acid is extracted from the root of the licorice plant; Glycyrrhiza glabra. It is a triterpene glycoside with glycyrrhetinic acid that possesses a wide range of pharmacological and biological activities. When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium glycyrrhizin. Glycyrrhizic...
Approved
Experimental
Matched Synonyms: … 18-beta-Glycyrrhizic acid
Matched Name: … Glycyrrhizic acid
Matched Iupac: … ]oxy}-5-{[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy}-3,4-dihydroxyoxane-2-carboxylic acid
Matched Description: … [T204] Glycyrrhizic acid has been developed in Japan and China as a hepatoprotective drug in cases of ... and biological activities. ... When extracted from the plant, it can be obtained in the form of ammonium glycyrrhizin and mono-ammonium …
Matched Categories: … glycyrrhizic acid ... Bile and Liver Therapy ... Alimentary Tract and Metabolism …
Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Synonyms: … Tauroursodesoxycholic acid
Matched Name: … Tauroursodeoxycholic acid
Matched Iupac: … -dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
Matched Description: … [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as ... and safety,[A249070] but a much higher hydrophilicity. ... a bile acid derivative. …
Matched Salts name: … Tauroursodeoxycholic acid dihydrate …
Matched Categories: … Taurodeoxycholic Acid ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …
Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Approved
Investigational
Matched Synonyms: … beta-betulinic acid
Matched Name: … Betulinic Acid
Matched Iupac: … 1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicosane-5-carboxylic acid
Matched Description: … Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Synonyms: … Gadopentetic acid ... Gadolinium diethylenetriamine pentaacetic acid
Matched Name: … Gadopentetic acid
Matched Description: … acid), that is given to enhance the image in cranial and spinal MRIs. ... A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … gadopentetic acid
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Synonyms: … Risedronic acid
Matched Name: … Risedronic acid
Matched Iupac: … [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of …
Matched Categories: … risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential ... risedronic acid ... Calcium-Regulating Hormones and Agents …
Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.[A957,L44788] Following administration, clorazepate is rapidly converted to nordiazepam (N-desmethyldiazepam), its active metabolite, before entering systemic circulation. Similar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA)...
Approved
Illicit
Matched Synonyms: … Clorazepic acid ... 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid
Matched Name: … Clorazepic acid
Matched Iupac: … 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
Matched Description: … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant ... other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid ... depression, coma, and death. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Iocetamic acid is a diagnostic aid (radiopaque medium)
Approved
Matched Synonyms: … Iocetamic acid
Matched Name: … Iocetamic acid
Matched Iupac: … 3-[N-(3-amino-2,4,6-triiodophenyl)acetamido]-2-methylpropanoic acid
Matched Description: … Iocetamic acid is a diagnostic aid (radiopaque medium) …
Matched Categories: … iocetamic acid
Approved
Experimental
Matched Synonyms: … Diphosphoric acid
Matched Name: … Pyrophosphoric acid
Matched Iupac: … (phosphonooxy)phosphonic acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid ... oxy-n-butyric acid ... 4-hydroxy-butyric acid
Matched Name: … gamma-Hydroxybutyric acid
Matched Iupac: … 4-hydroxybutanoic acid
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched International brands: … Nal-acid
Matched Synonyms: … Nalidixic acid ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid
Matched Name: … Nalidixic acid
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Categories: … nalidixic acid
Eurotium amstelodami allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, aspergillus amsterdami …
Displaying drugs 2876 - 2900 of 15333 in total