Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Did you mean bitopertin of rp 493838 of r 18 of ビトペルチン?
Displaying drugs 2951 - 2975 of 9629 in total

Entrectinib

Entrectinib is a tropomyosin receptor tyrosine kinase (TRK) TRKA, TRKB, TRKC, proto-oncogene tyrosine-protein kinase ROS1, and anaplastic lymphoma kinase (ALK) inhibitor. It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic non-small cell lung cancer and NTRK gene fusion positive solid tumors. Entrectinib's...
Approved
Investigational
Matched Description: … [L8081] It was approved by the FDA in August 2019 for use in the treatment of ROS1-positive metastatic ... [L8207] Entrectinib's approved use is meant as a last line of therapy due to its accelerated approval ... over similar ALK inhibitors such as [alectinib], [ceritinib], and [lorlatinib] due to a wider range of …

Bronopol

Bronopol, or 2-Bromo-2-nitro-1,3-propanediol, is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives . Bronopol is used as a microbicide or microbiostat...
Approved
Matched Description: … The agent is largely available commercially as an antibacterial for a variety of industrial purposes ... Nevertheless, ongoing contemporary re-evaluations of bronopol use in large markets such as Canada now ... ] and in other products where it may not primarily be used in the role of a non-medicinal preservative …

Desirudin

Desirudin is a direct inhibitor of human thrombin. It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. Hirudin is a single polypeptide chain of 65 amino acids residues and contains three disulfide...
Approved
Matched Description: … Desirudin has a chemical formula of C287H440N80O110S6 with a molecular weight of 6963.52. ... Desirudin is a direct inhibitor of human thrombin. ... It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant …

Angiotensin II

Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and Acute Renal Failure. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy. As of December 21, 2017 the FDA approved La Jolla Pharmaceutical's...
Approved
Investigational
Matched Description: … The novelty of the medication lies in the fact that it is the first and only use of synthetic human angiotensin ... Angiotensin II is under investigation for the treatment of Sepsis, Septic Shock, Diabetes Mellitus, and ... Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Description: … the dementia of Alzheimer's Disease, and in some cases, is used to manage other types of dementia. ... the symptoms of its associated dementia. ... increase from a global prevalence of 20.2 million in 1990. …

Acetylsalicylic acid

Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction...
Approved
Vet approved
Matched Description: … Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic ... It should be kept out of reach from young children, toddlers, and infants [FDA label]. ... Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain …
Matched Mixtures name: … CAFIASPIRINA(R) COMPRIMIDOS ... Bubbles R Better Effervescent Cold Relief …

Formestane

Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. Formestane suppresses estrogen production from anabolic steroids or prohormones. Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity and mild aromatase inhibitor activity....
Approved
Investigational
Withdrawn
Matched Description: … Some clinical data has suggested that the clinically recommended dose of 250mg was too low. ... Formestane is also a prohormone of 4-hydroxytestosterone, an active steroid with weak androgenic activity ... Formestane was the first selective, type I, steroidal aromatase inhibitor used in the treatment of estrogen-receptor …

Dinoprostone

Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved

Sugammadex

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intubation that patients may require...
Approved
Matched Description: … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced ... Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help …

Recombinant stabilized RSV A prefusion F antigen

Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial virus (RSV) vaccine called Abrysvo. The vaccine comprises two antigens - the other being recombinant stabilized RSV A prefusion F antigen - which have been expressed in Chinese hamster ovary cell lines and then purified...
Approved
Matched Description: … through six months of age. ... Recombinant stabilized RSV B prefusion F antigen is one component of a bivalent respiratory syncytial ... [L48066] Abrysvo was first approved by the FDA in May 2023 for use in patients ≥60 years of age, and …

Protirelin

Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing hormone (TRH). It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid Stimulating Hormone (TSH) and prolactin from the anterior pituitary. Although not currently available in any FDA-approved product, protirelin is a...
Approved
Investigational
Matched Description: … Protirelin is the pharmaceutically available synthetic analogue of the endogenous peptide thyrotropin-releasing ... It is a tri-peptide tropic hormone, released by the hypothalamus, that stimulates the release of Thyroid ... Although not currently available in any FDA-approved product, protirelin is a component of the TRH Test …

Juglans regia pollen

Juglans regia pollen is the pollen of the Juglans regia plant. Juglans regia pollen is mainly used in allergenic testing.
Approved
Matched Description: … Juglans regia pollen is the pollen of the Juglans regia plant. …

Rhizopus stolonifer

Rhizopus stolonifer is a fungus which can provoke allergic reactions. Rhizopus stolonifer extract is used in allergenic testing.
Approved

Dihydrostreptomycin

Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.
Approved
Investigational
Vet approved
Withdrawn
Matched Description: … In humans, the use of dihydrostreptomycin has been associated with ototoxicity. ... The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate …

Ceftobiprole medocaril

Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(N-hydroxyimino)acetamido]-3-{[(3E,3'R)-1'-{[(5-methyl …
Matched Description: … Ceftobiprole medocaril is a prodrug of [ceftobiprole], a fifth-generation semisynthetic cephalosporin ... activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of ... medocaril in February 2010, recommending the refusal of its marketing authorization in the European …

Flotufolastat F-18

Flotufolastat F-18 (18F-rhPSMA-7.3) is an 18F-labeled ligand that targets the prostate-specific membrane antigen (PSMA).[A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of 18F-labeled ligands for positron emission tomography (PET) offers accurate diagnostic imaging. Unlike 68Ga-labeled PSMA-targeting ligands, 18F-labeled compounds targeting this protein have a longer...
Approved
Investigational
Matched Description: … [A259846] In May 2023, the FDA approved the use of flotufolastat F-18 for PET of PSMA-positive lesions ... a high level of accumulation in tumors. ... A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of …

Arsenic trioxide

Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous ... Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Description: … that contains 191 amino acid residues with a molecular weight of 22 kDa. ... known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of ... [A228183] Growth hormone therapy is approved for various disorders of growth hormone deficiency, …

Abrocitinib

Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). Janus kinases are intracellular enzymes involved in transduction pathways that regulate hematopoiesis and immune cell function. The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway plays a central role in the pathogenesis of a variety of...
Approved
Investigational
Matched Description: … plays a central role in the pathogenesis of a variety of autoimmune and inflammatory diseases, including ... Abrocitinib is an oral small-molecule inhibitor of Janus kinase 1 (JAK1). ... [L39774] The Janus kinase (JAK)–signal transducer and activator of transcription (STAT) signalling pathway …

Chloramphenicol succinate

Chloramphenicol succinate is an ester prodrug of chloramphenicol. Chloramphenicol is a bacteriostatic antibiotic. Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias. Chloramphenicol succinate was granted FDA approval on 20 February 1959.
Approved
Matched Description: … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially ... Chloramphenicol succinate is an ester prodrug of [chloramphenicol]. …

Ganirelix

Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction …

Apremilast

Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Description: … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of ... [L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated …

Enzacamene

Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved

Ocrelizumab

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS). It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively targets B-cells that express the CD20 antigen. Compared to non-humanized CD20 antibodies such as rituximab, ocrelizumab is...
Approved
Investigational
Matched Description: … Primary progressive multiple sclerosis (PPMS) accounts for 10-15% of the overall population of patients ... In clinical trials of patients with relapsing forms of MS, treatment with ocrelizumab resulted in reduced ... progressive or relapsing forms of multiple sclerosis (MS). …

Triazolam

Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Approved
Investigational
Matched Description: … Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. …
Displaying drugs 2951 - 2975 of 9629 in total