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Displaying drugs 276 - 300 of 9132 in total
Canakinumab is a recombinant, human anti-human-IL-1β monoclonal antibody that belongs to the IgG1/κ isotype subclass. It is expressed in a murine Sp2/0-Ag14 cell line and comprised of two 447- (or 448-) residue heavy chains and two 214-residue light chains, with a molecular mass of 145157 Daltons when deglycosylated. Both heavy...
Approved
Investigational
Matched Description: … Canakinumab is marketed under the brand name Ilaris and indicated for patients 4 years of age and older …
Matched Products: … IBECTA 150 MG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 4 ADET …
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Approved
Experimental
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 6,7-Dimethyl-9-D-ribitylisoalloxazine ... 7,8-Dimethyl-10-ribitylisoalloxazine ... 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine …
Matched Iupac: … 7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]-2H,3H,4H,10H-benzo[g]pteridine-2,4-dione …
Matched Mixtures name: … Protect Plus SO 60 ... Pregvit Folic 4 ... PreQue 10
Matched Products: … บี 2 - 10 ... ยาเม็ดวิตามิน บี 2 10 มก. ... RIBOFLAVIN TABLETS 10 MG. …
Paricalcitol is a synthetic vitamin D analog. Paricalcitol has been used to reduce parathyroid hormone levels. Paricalcitol is indicated for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.
Approved
Investigational
Matched Iupac: … 2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4- …
Matched Products: … ZEMPLAR 4 MCG YUMUŞAK KAPSÜL, 28 ADET ... PAKSİTU 10 MCG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... RECHROSİTOL 10 MCG/ML I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others. As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Iupac: … 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide …
Matched Products: … CALQUENCE 100 MG SERT KAPSÜL, 60 ADET …
Duchenne muscular dystrophy (DMD) is an X-linked recessive allelic disorder characterized by a lack of functional dystrophin protein, which leads to progressive impairment of ambulatory, pulmonary, and cardiac function and is invariably fatal. A related, albeit a less severe, form of muscular dystrophy known as Becker muscular dystrophy (BMD) is...
Approved
Investigational
Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Salts cas: … 13446-34-9
Matched Mixtures name: … TRACUTIL® 10 ML AMPOLLAS ... Protect Plus SO 60 ... Classic Swiss One 10 Multivitamin and Mineral Tab …
Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Products: … DIDRONAT 200 MG TABLET, 60 ADET …
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Products: … RATEBİR 250 MG TABLET, 60 ADET ... ABYGA 500 MG FİLM KAPLI TABLET, 60 ADET ... ZYTİGA 500 MG FİLM KAPLI TABLET, 60 ADET …
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Salts cas: … 33952-38-4
Matched Mixtures name: … LOMOTİL 2.5 MG + 0.025 MG / 5 ML ORAL ÇÖZELTİ, 60 ML …
Matched Products: … ATROPİN SÜLFAT 1/4 MG AMPUL , 10 ADET ... ATROPIN SÜLFAT 1/4 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL ... DROGSAN ATROPIN SULFAT 1/4 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL …
Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Iupac: … N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide …
Matched Products: … CABOMETYX 60 MG FİLM KAPLI TABLET, 30 ADET …
An important regulator of gene expression during growth and development, and in neoplasms. Tretinoin, also known as retinoic acid and derived from maternal vitamin A, is essential for normal growth; and embryonic development. An excess of tretinoin can be teratogenic. It is used in the treatment of psoriasis; acne vulgaris;...
Approved
Investigational
Matched Synonyms: … 9-cis-Tretinoin ... 9(Z)-Retinoic acid ... 9-cis-retinoic acid …
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Mixtures name: … Clindamycin 1% / Niacinamide 4% / Tretinoin 0.05% …
Matched Products: … Alitretan 10 mg Kapseln ... TOCTINO 10 mg Weichkapseln …
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Iupac: … (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid …
Matched Salts cas: … 76095-16-4
Matched Mixtures name: … ENALAPRIL/LERCA MIC 10/10 ... ENALAPRIL/LERCA MIC 10/10 ... ENALAPRIL/LERCA MIC 10/10
Matched Products: … KONVERIL 10 MG TABLET, 60 ADET ... KONVERIL 5 MG TABLET, 60 ADET ... ENAPRIL-10 TABLET 10 mg …
Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.[A203597,A203618] Apomorphine...
Approved
Investigational
Matched Iupac: … (9R)-10-methyl-10-azatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadeca-1(16),2(7),3,5,13(17),14-hexaene-3,4 …
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Matched Products: … APO-GO PEN 10 MG/ML ... APO-GO (AMPOULE 10 MG/ML) ... Apo-go Pen 10 mg/ml - Injektionslösung …
A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Tacrine has been discontinued for the United States market.
Approved
Investigational
Withdrawn
Matched Synonyms: … 1,2,3,4-tetrahydro-9-acridinamine ... 1,2,3,4-tetrahydro-9-aminoacridine ... 1,2,3,4-tetrahydroacridin-9-amine …
Matched Iupac: … 1,2,3,4-tetrahydroacridin-9-amine …
Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Synonyms: … 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone ... 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methyl-p-benzoquinone ... 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-p-benzoquinone …
Matched Iupac: … 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione …
Matched Mixtures name: … SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 28 ADET ... SALPEZIL 90/10 MG FILM KAPLI TABLET ,TABLET, 84 ADET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET …
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Mixtures name: … TRIZIVIR FILM TABLET, 60 ADET …
Matched Products: … MIVUX 150 MG FILM TABLET, 60 ADET ... MIVUX 300 MG FILM KAPLI TABLET, 60 ADET ... EPIVIR 150 MG FİLM KAPLI TABLET, 60 ADET …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Products: … LUDIOMIL 25 MG TABLET, 60 ADET …
Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b. It was developed by Bristol-Myers Squibb Canada and approved by Health Canada on...
Approved
Investigational
Withdrawn
Matched Iupac: … tert-butyl N-[(2S)-1-[(2S,4R)-4-[(7-chloro-4-methoxyisoquinolin-1-yl)oxy]-2-{[(1R,2S)-1-[(cyclopropanesulfonyl …
A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.
Approved
Isoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
Approved
Matched Mixtures name: … TRODERM 10 MG/G+1 MG/G KREM ,15 G ... TRAVOCORT 10 mg/g+1 mg/g KREM, 15 G ... TİNAGEN 1 MG+10 MG/1 G DERİ KREMİ, 15 G …
Matched Products: … TRAVOGEN KREM, 60 G …
A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.
Approved
Matched Synonyms: … (11β,16α)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione …
Matched Iupac: … (1S,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-10-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H …
Matched Mixtures name: … Desoximetasone 0.05% / Niacinamide 4% ... Desoximetasone 0.05% / Niacinamide 4% ... Desoximetasone 0.05% / Niacinamide 4% …
Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product in the physiological pathway of vitamin A metabolism. In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant,...
Approved
Investigational
Nutraceutical
Matched Synonyms: … (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid ... 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL) …
Matched Iupac: … (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid …
Matched Description: … A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4
Matched Mixtures name: … Acnatac 10 mg/g + 0,25 mg/g Gel ... Niacinamide 4% / Tretinoin 0.1% ... Niacinamide 4% / Tretinoin 0.05% …
Matched Products: … AKNEVIT SOLÜSYON, 60 ML ... VESANOID® 10 MG. ... Vesanoid 10 mg Kapseln …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It also consists up to 4% linoleic, 3% oleic, 1% stearic, and less than 1% linolenic fatty acids [A31170 …
Matched Mixtures name: … HydroGold 9
Matched Products: … RICILAKS 60 ML EMULSIYON …
Displaying drugs 276 - 300 of 9132 in total