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Displaying drugs 276 - 300 of 8849 in total

Relatlimab

Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013, and has garnered interest in the treatment of a variety of cancers, including leukemia and melanoma. As immune checkpoint...
Approved
Investigational
Matched Description: … (LAG-3). ... [L41265,L41300] It was the first anti-LAG-3 antibody to demonstrate benefit in a Phase 3 study, as well ... IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 …
Matched Categories: … Lymphocyte Activation Gene-3 Blocker …

Everolimus

Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as an mTOR (mammalian target of rapamycin) inhibitor. It is currently used as an immunosuppressant to prevent rejection of organ transplants. In a similar fashion to other mTOR inhibitors Everolimus' effect is solely on the mTORC1 protein and...
Approved
Matched Iupac: … ,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3- …
Matched Products: … AFINITOR (3 MG DISPERSIBLE TABLETS) …

Pegvisomant

Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly. Unlike dopamine or somatostatin analogs (which inhibit growth hormone secretion), this drug actually blocks the hepatic (GH-mediated) production of insulin like growth factor (IGF-1), which is the main mediator of growth hormone activity.
Approved

Romiplostim

Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Description: … FDA approved on August 22, 2008. …

Iopodic acid

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Iupac: … 3-(3-{[(dimethylamino)methylidene]amino}-2,4,6-triiodophenyl)propanoic acid …
Matched Description: … On September 22, 1981, ipodate was submitted again by the company Schering AG but it is currently under …
Matched Salts cas: … 1221-56-3 …

Epcoritamab

Epcoritamab is an IgG1-bispecific antibody that simultaneously binds to CD3 on T-cells and CD20 on B-cells.[A259736,A258488,A259761,L46516] Epcoritamab promotes the activation and expansion of T-cells and, by being able to bind to both CD20 and CD3, it leads to the T-cell–mediated killing of CD20+ malignant B cells.[A259761,L46516] Diffuse large B-cell lymphoma...
Approved
Investigational

Amrinone

Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Approved
Matched Description: … Amrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. …
Matched Categories: … Phosphodiesterase 3 Inhibitors …

Adenine

A purine base and a fundamental unit of adenine nucleotides.
Approved
Nutraceutical
Matched Salts cas: … 2922-28-3 …
Matched Mixtures name: … As 3 ... Additive Solution Formula 3 As-3 ... As-3 …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Products: … Ultradex Liq 3% ... Suite Scrub Foam Liq 3% ... Suite Scrub 1000 Liq 3% …

Cladosporium sphaerospermum

Cladosporium sphaerospermum is a fungus which can provoke allergic reactions. Cladosporium sphaerospermum extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …

Xanthium strumarium pollen

Xanthium strumarium pollen is the pollen of the Xanthium strumarium plant. Xanthium strumarium pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 3 Weed Mix ... 3 Weed Mix ... 3 Weed Mix …

Spectinomycin

An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.
Approved
Investigational
Vet approved
Matched Salts cas: … 23312-56-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Naloxegol

Naloxegol, for "PEGylated naloxol" is a peripherally-selective opioid antagonist developed by AstraZeneca. It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain. The advantage of naloxegol over the opioid antagonist naloxone is that its...
Approved
Matched Iupac: … (1S,5R,13R,14S,17S)-14-(2,5,8,11,14,17,20-heptaoxadocosan-22-yloxy)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo …

Aspergillus niger var. niger

Aspergillus niger var. niger is a fungus which can provoke allergic reactions. Aspergillus niger var. niger extract is used in allergenic testing.
Approved
Matched Mixtures name: … Mold Mix 3 ... Mold Mix 3 ... Mold Mix 3 …

Benzalkonium

Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Mixtures name: … Refill 3 ... 3-Step First Aid Kit ... 3 Step First Aid Kit …
Matched Products: … 3 Pack Scented Hand Sanitizer ... ISSENGARD 24 HAND SANITIZER 3 oz ... Tsum Tsum 3 Pack Hand Sanitizer TT0051WA …

Capivasertib

Hormone receptor (HR) positive, especially estrogen receptor-positive, HER2-negative breast cancer is the most common subtype of metastatic breast cancer, resulting in more than 400,000 deaths annually. Although endocrine-based therapy is the first line of treatment, resistance eventually emerges, leaving chemotherapy the only but often ineffective treatment left. Therefore, significant research...
Approved
Investigational
Matched Iupac: … 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperidine-4-carboxamide …

Nitazoxanide

Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Mixtures name: … REFRESH Optive Mega-3 ... REFRESH Optive Mega-3 ... Xoul Cell Illuminating 3 Step Mask …
Matched Products: … SRB 3 Lighting White Nutri ... 3 en 1 Cleanser. Deep Cleansing ... Eros Extended Love 3 Top Level …

Acer saccharinum pollen

Acer saccharinum pollen is the pollen of the Acer saccharinum plant. Acer saccharinum pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … 3 Maple Pollen Mix ... 3 Maple Pollen Mix ... 3 Maple Pollen Mix …

Dihydrocodeine

Dihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of...
Approved
Illicit
Matched Salts cas: … 84824-87-3 …

Clothiapine

Clothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.
Approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Mixtures name: … Additive Solution Formula 3 As-3 ... As-3 ... D-5-1/3 S …

Voxilaprevir

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Iupac: … methoxy-22,25-dioxo-2,21-dioxa-4,11,23,26-tetraazapentacyclo[24.2.1.0^{3,12}.0^{5,10}.0^{18,20}]nonacosa-3( …
Matched Description: … replication of HCV genetic material and translation into a single polypeptide, Nonstructural Protein 3 ... Vosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, 3, ... genotypes 1-6 who have been previously treated with an NS5A inhibitor, or patients with genotypes 1a or 3 …

Platanus racemosa pollen

Platanus racemosa pollen is the pollen of the Platanus racemosa plant. Platanus racemosa pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Western 3 Tree Pollen Mix ... Western 3 Tree Pollen Mix …
Displaying drugs 276 - 300 of 8849 in total