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Displaying drugs 276 - 300 of 8614 in total
N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)
N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties.
Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Vamorolone
Vamorolone is a novel and fully synthetic glucocorticoid developed by Santhera Pharmaceuticals. It is used to manage inflammation and immune dysregulation in patients with Duchenne muscular dystrophy (DMD), a neuromuscular disorder characterized by the insidious regression of neuromuscular function and the most common form of muscular dystrophy in the United...
Approved
Investigational
Matched Description: … [L48671,L48676] In December 2023, it was approved in the EU for the treatment of patients ≥4 years of …
Anakinra
Anakinra is a recombinant human interleukin-1 (IL-1) receptor antagonist (IL-1Ra) composed of 153 amino acid residues. Unlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. This drug binds to the IL-1 receptor, competing with and inhibiting the activity of IL-1 alpha and beta. Anakinra is...
Approved
Investigational
Matched Description: … On November 14, 2001, it was approved by the FDA for the treatment of rheumatoid arthritis. …
Berberine
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Approved
Investigational
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Hepatitis B immune globulin
Long-term hepatitis B immune globulin (HBIG) has been shown to reduce hepatitis B virus (HBV) reinfection in patients transplanted for hepatitis B. Infection with hepatitis B may lead to hepatocellular carcinoma, a type of liver cancer. Therefore, the hepatitis-B vaccines are cancer-preventing vaccines. According to the Centers for Disease Control...
Approved
Investigational
Matched Products: … ./4 ml …
Axicabtagene ciloleucel
Axicabtagene ciloleucel is an anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. The drug has a unique mechanism of action, as it utilizes the patient's own T cells, which play a central role in immune response to cancer. Once T-cells are collected from the patient, they are genetically engineered to express...
Approved
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Iupac: … 4-[(1R,3aS,3bR,5aS,7S,9R,9aR,9bS,10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[ …
Valine
Valine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Approved
Nutraceutical
Matched Mixtures name: … Bcaa 4% Inj ... VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 ML ... VAMIN 14 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML …
Bupivacaine
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Pro-C-Dure 4 Kit ... BUVACAINA® PESADA SOLUCION INYECTABLE 20 MG/ 4 ML …
Matched Products: … MARCAINE SPINAL HEAVY %0,5 ENJEKSİYONLUK SOLUSYON ICEREN AMPUL, 4 ML X 5 ADET …
Matched Products: … MARCAINE SPINAL HEAVY %0,5 ENJEKSİYONLUK SOLUSYON ICEREN AMPUL, 4 ML X 5 ADET …
Ulipristal
Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to...
Approved
Matched Iupac: … (10S,11S,14R,15S,17R)-14-acetyl-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyltetracyclo[8.7.0.0^{ …
Matched Salts cas: … 126784-99-4 …
Matched Salts cas: … 126784-99-4 …
Gefapixant
It has been estimated that 5-10% of adults globally suffer from chronic cough, which is defined as a cough lasting longer than eight weeks. A subset of these patients remain symptomatic despite thorough investigation and treatment, termed refractory chronic cough (RCC) if they have a cough that does not respond...
Approved
Investigational
Matched Iupac: … 5-[(2,4-diaminopyrimidin-5-yl)oxy]-2-methoxy-4-(propan-2-yl)benzene-1-sulfonamide …
Cryptenamine
Cryptenamine is a mixture of closely related hypotensive alkaloids from Veratrum album (Liliaceae). It has been used in the treatment of hypertension but has largely been replaced by drugs with fewer adverse effects. Cryptenamine has a marked and re-producible depressor effect when given intravenously to hypertensive patients, however the mechanism...
Approved
Matched Categories: … Heterocyclic Compounds with 4 or More Rings …
Enfortumab vedotin
Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers. It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable link. It is similar to brentuximab vedotin, another...
Approved
Investigational
Matched Description: … to [brentuximab vedotin], another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4. ... [L10836] It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting …
Matched Categories: … Nectin-4-directed Antibodies …
Matched Categories: … Nectin-4-directed Antibodies …
Neratinib
Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Approved
Investigational
Matched Iupac: … (2E)-N-[4-({3-chloro-4-[(pyridin-2-yl)methoxy]phenyl}amino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino …
Omalizumab
Omalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). IgE promotes the release of inflammatory mediators from mast cells and basophils during allergic and inflammatory reactions. By binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its...
Approved
Investigational
Tafluprost
A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Iupac: … propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl …
Benzalkonium
Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Salts cas: … 91080-29-4 …
Matched Mixtures name: … 14-Panel Toxicology Medicated Collection System ... Hands First 4 in 1 ... Adventure Medical Kits 1-4 Person First Aid …
Matched Products: … Hand Sanitizer Secret Pets 4-pack secret pets 4 pack ... Hand Sanitizer Secret Pets 4 Pack Secret Pets 4 Pack ... Emoji 4 Pack Hand Sanitizer …
Matched Mixtures name: … 14-Panel Toxicology Medicated Collection System ... Hands First 4 in 1 ... Adventure Medical Kits 1-4 Person First Aid …
Matched Products: … Hand Sanitizer Secret Pets 4-pack secret pets 4 pack ... Hand Sanitizer Secret Pets 4 Pack Secret Pets 4 Pack ... Emoji 4 Pack Hand Sanitizer …
Ifosfamide
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Approved
Romiplostim
Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to increase platelet production through activation of the thrombopoietin receptor. The peptibody molecule has two identical single-chain subunits, each one is made up of 269 amino acid residues. Each subunit consists of an IgG1 Fc carrier domain that is covalently...
Approved
Matched Description: … Each domain consists of 14 amino acids. …
Norelgestromin
Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.
Approved
Investigational
Matched Iupac: … -14-ol ... (1S,2R,10R,11S,14R,15S)-15-ethyl-14-ethynyl-5-(hydroxyimino)tetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-6-en …
Tibolone
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha .
Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Iupac: … (1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-2(7) …
Matched Description: … Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses …
Matched Description: … Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses …
Megestrol acetate
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Approved
Investigational
Vet approved
Matched Iupac: … -14-yl acetate ... (1S,2R,10R,11S,14R,15S)-14-acetyl-2,8,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14 ... = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, ... IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4- …
Matched Mixtures name: … Pregvit Folic 4 ... . #4 Vitamin and Mineral Dietary Supplement …
Matched Mixtures name: … Pregvit Folic 4 ... . #4 Vitamin and Mineral Dietary Supplement …
Phenylalanine
Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.
Approved
Investigational
Nutraceutical
Matched Mixtures name: … VAMIN 14 IV AMINOASIT SOLÜSYONU, 500 ML ... VAMIN 14 EF ELEKTROLITSIZ AMINOASİT SOLÜSYON, 500 ML ... NUTRINEAL PD-4 PERITONEAL DIALYSIS SOLUTION WITH 1.1% AMINO ACIDS …
Displaying drugs 276 - 300 of 8614 in total