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Displaying drugs 276 - 300 of 3811 in total
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Iupac: … dimethylamino)propylidene]-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-5-yl]acetic acid
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating ... inflammatory and allergic reactions. …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief ... OLO-A-DAY …
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Coenzyme R ... (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid ... 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid
Matched Iupac: … 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid
Matched Description: … and milk. ... It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, ... A water-soluble, enzyme co-factor present in minute amounts in every living cell. …
Matched Mixtures name: … Folivane-Plus with Ascorbic Acid Precursors ... Lipo-B-C Tab ... B-complex With Vitamin C, Biotin, Folic Acid
Matched Categories: … Enzymes and Coenzymes ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Coenzymes
Matched Products: … Biona-vit Controls and Prevents Hair Loss ... D-biotin Tab 5mcg A Croquer …
Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens …
Matched Description: … and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed ... across various SCLC disease stages and treatment statuses. ... [L50743,A263808] Its bispecificity causes T-cell activation, the release of inflammatory cytokines, and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … immunoglobulin g1 (igg1) t-cell bispecific (tcb) antibody targeting carcinoembryonic antigen (cea) and
Matched Categories: … Amino Acids, Peptides, and Proteins …
Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant lymphocytes.
Investigational
Matched Synonyms: … Murine MAb (Lym-1) and Iodine 131-I radiolabeled murine MAb (Lym-1) to human B-cell lymphoma …
Matched Description: … Lym-1-I-131 is a monoclonal antibody labeled with iodine-131 (131I) that preferentially targets malignant …
Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit(t-cell immunoreceptor with ig and itim domains)) (humanized …
Matched Description: … Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab …
Platango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements. Its potential benefit in maintaining remission in ulcerative colitis has been studied . Regardless, this agent is most predominantly used as...
Approved
Investigational
Matched Description: … It is found in some laxatives for treating occasional constipation and restoring regularity in bowel ... Regardless, this agent is most predominantly used as a gentle laxative agent in many parts of the world ... that is more commonly referred as psyllium or psyllium husk. …
Matched Categories: … Herbs and Natural Products …
Matched Products: … Up and Up Fiber Therapy ... up and up fiber therapy Natural Fiber ... Lidl Orange Smooth Fiber Powder Naturally and Artificially Flavored …
Investigational
Matched Synonyms: … and a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase ... recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) …
Atidarsagene autotemcel, sold under the brand name Libmeldy, is a gene therapy comprising genetically modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. Libmeldy was granted orphan designation by the EMA in April 2007, and was...
Approved
Matched Synonyms: … Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC ... deoxyribonucleic acid sequence ... ) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene …
Matched Description: … modified autologous CD34+ enriched hematopoietic stem and progenitor cells transduced _ex vivo_ using ... [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing ... a lentiviral vector encoding the human arylsulfatase A (ARSA) gene. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Autologous Hematopoietic Stem Cell-Based Gene Therapy …
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity ... Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal ... In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol …
Matched Mixtures name: … Ophtrivin A Ophthalmic Dps …
Matched Categories: … Decongestants and Antiallergics ... Sympathomimetics Used as Decongestants ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …
Investigational
Matched Synonyms: … antibody-drug conjugate comprised of a human aglycosylated anti-CD74 IgG1 antibody (SP7219) and two non-cleavable ... STRO-001, a site-specific anti-CD74 antibody-drug conjugate …
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … alpha (α)-adrenergic properties. ... ] that is used as an ocular and nasal decongestant. ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral …
Matched Mixtures name: … Redness reliever and Lubricant ... Up and Up Ultra Itchy Relief ... Seasonal itchy and Red eye relief …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Sympathomimetics Used as Decongestants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops ... VISINE YXIN 0.5MG/ML ATR
A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Approved
Investigational
Matched Description: … A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations. …
Matched Mixtures name: … Systane Day and Night Value Pack ... Systane Day and Night Value Pack ... Walgreens Lubricant Eye Drops Dry Eye 15mL and twin pack …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Eyelash and Eyebrow Lengthener ... RITE AID Lubricant Drops …
Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but ... Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species. …
Matched Mixtures name: … Lice-Nil Lice and Eggs Killer ... Medi and Lice Lice Killing ... Weeks and Leo Complete Lice Treatment …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Investigational
Matched Synonyms: … scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and
Matched Description: … Acapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND ON N6 OF LYSYL RESIDUES (K) WITH AN ... ON N.ALPHA..1ALANINE AND N6 OF LYSINE RESIDUES WITH ... POLY(OXY-1,2-ETHANEDIYL), .ALPHA.-CARBOXY-.OMEGA. …
Matched Description: … in alanine and lysine residues. ... in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents ... Adenosine Deaminase Inhibitors ... Recombinant Adenosine Deaminases …
Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-resistant Prostate Cancer).
Investigational
Matched Synonyms: … ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4, CD152)), CHIMERIC, HOMO SAPIENS AND ... MMUNOGLOBULIN G4 SCFV-H-CH2-CH3_SCFV, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD1, PD-1, CD279)) AND
Matched Description: … Lorigerlimab is under investigation in clinical trial NCT05848011 (A Study of Lorigerlimab With Docetaxel …
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. ... It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. ... Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium …
Matched Mixtures name: … GIN-III Alpha and Omega GIN Sun ... Oars and Alps SPF 50 100% Mineral Antioxidant Sunscreen ... Hyaluronic Acid Watery Sun …
Matched Categories: … Astringents and Deodorants ... Compounds used in a research, industrial, or household setting …
Matched Products: … Quick and Clean Oil Free Sun Spf35 Pa ... Im Safe for Baby and Silver ... Peaufinee Baby and Kids Sun …
evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)).
Investigational
Matched Synonyms: … protein alpha (SIRPalpha) variant 1 (v1) genetically linked to a modified and inactive Fc domain of ... A CD47-binding, fusion protein containing a high affinity engineered D1 domain of human signal regulatory …
Matched Description: … Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)). ... evorpacept is under investigation in clinical trial NCT04755244 (A Study of Evorpacept (ALX148) With …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … It also consists up to 4% linoleic, 3% oleic, 1% stearic, and less than 1% linolenic fatty acids [A31170 ... fatty acid [A31170], castor oil has been used as a vital raw material for the chemical industry [A33045 ... and mineral oral tablets as an ingredient for protective coatings. …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil ... Rite Aid Castor Oil ... Well at Walgreens Castor Oil …
Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …
Matched Description: … It is not an approved drug. ... Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Mixtures name: … Ari S-Liner …
Matched Products: … Ari S-Liner …
DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and
Matched Description: … DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). ... in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy). ... DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening ... with aspartic acid. ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … .Insulin Aspart Protamine and Insulin Aspart ... Insulin Aspart Protamine and Insulin Aspart Mix 70/30 …
Demplatin pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and Gemcitabine Versus Gemcitabine Alone in Pancreatic Cancer).
Investigational
Matched Synonyms: … A micelle drug formulation composed of cisplatin and mPEG-poly(l-Glu) diblock copolymer with 1,3-propanediyl …
Matched Description: … pegraglumer is under investigation in clinical trial NCT02043288 (Combination Therapy With NC-6004 and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Amino Acids, Dicarboxylic …
Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme A, which acts as a cofactor in many enzymatic reactions that...
Approved
Matched Description: … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and ... Dexpanthenol is enzymatically cleaved to form pantothenic acid, which is an essential component of Coenzyme ... ) and the levorotatory form (levopanthenol) as [DB11204]. …
Matched Mixtures name: … Somarexin and C 1000 ... B Complex W C and B12 Inj ... CH6 Perfumed Aloforthya Peony and the sunset …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Vitamin D and Analogues ... Preparations for Treatment of Wounds and Ulcers ... Amino Acids
Matched Products: … Eros Aqua Sensations and Care Woman ... DEXPANTHENOL ACIS WUND+HEI ... DEXPANTHENOL AXI W+H50MG/G …
Displaying drugs 276 - 300 of 3811 in total